Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

The Immunoglobulin Superfamily—Domains for Cell Surface Recognition

1988 • 2,237 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Altering the Genome by Homologous Recombination

1989 • 2,021 citations

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1992 • 1,632 citations

Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing

1987 • 1,134 citations

An Improved Method for Prenatal Diagnosis of Genetic Diseases by Analysis of Amplified DNA Sequences

1987 • 811 citations

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

1984 • 739 citations

Neural cell adhesion molecules and myelin-associated glycoprotein share a common carbohydrate moiety recognized by monoclonal antibodies L2 and HNK-1

1984 • 723 citations

CELL ADHESION MOLECULES: Implications for a Molecular Histology

1991 • 707 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

Kinetics of homophilic binding by embryonic and adult forms of the neural cell adhesion molecule.

1983 • 635 citations

Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin

1985 • 538 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve.

1986 • 482 citations

PROTEIN COMPOSITION OF MYELIN OF THE PERIPHERAL NERVOUS SYSTEM

1973 • 446 citations

Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

1991 • 394 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

J1/tenascin is a repulsive substrate for central nervous system neurons

1990 • 380 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and myelin-associated glycoprotein) in regenerating adult mouse sciatic nerve.

1988 • 364 citations

Role of myelin Po protein as a homophilic adhesion molecule

1990 • 344 citations

Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations

1990 • 340 citations

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction.

1987 • 335 citations

Two forms of 1B236/myelin-associated glycoprotein, a cell adhesion molecule for postnatal neural development, are produced by alternative splicing.

1987 • 320 citations

The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions.

1990 • 305 citations

The 180-kD component of the neural cell adhesion molecule N-CAM is involved in cell-cell contacts and cytoskeleton-membrane interactions

1987 • 303 citations

Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors

1991 • 296 citations

Three markers of adult non-myelin-forming Schwann cells, 217c(Ran-1), A5E3 and GFAP: development and regulation by neuron–Schwann cell interactions

1990 • 277 citations

Protein zero of peripheral nerve myelin: Biosynthesis, membrane insertion, and evidence for homotypic interaction

1990 • 276 citations

Unwrapping the genes of myelin

1988 • 246 citations

Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

1992 • 197 citations

Target frequency and integration pattern for insertion and replacement vectors in embryonic stem cells.

1991 • 187 citations

Immunocytochemical localization of P0 protein in Golgi complex membranes and myelin of developing rat Schwann cells.

1981 • 184 citations

Expression of the neural cell adhesion molecules L1 and N-CAM and their common carbohydrate epitope L2/HNK-1 during development and after transection of the mouse sciatic nerve

1985 • 183 citations

Functional cooperation between the neural adhesion molecules L1 and N-CAM is carbohydrate dependent.

1990 • 174 citations

Enhanced expression of the extracellular matrix molecule J1/tenascin in the regenerating adult mouse sciatic nerve

1990 • 162 citations

Biosynthesis and membrane topography of the neural cell adhesion molecule L1.

1985 • 157 citations

Myelin‐specific proteolipid protein is expressed in myelinating schwann cells but is not incorporated into myelin sheaths

1987 • 154 citations

Recombinant peripheral myelin protein P_o confers both adhesion and neurite outgrowth‐promoting properties

1990 • 133 citations

Distribution of the adhesion molecules N-CAM and L1 on peripheral neurons and glia in adult rats

1986 • 127 citations

Different extracellular domains of the neural cell adhesion molecule (N-CAM) are involved in different functions.

1992 • 117 citations

Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms.

1990 • 116 citations

The peripheral myelin glycoprotein P0 expresses the L2/HNK-1 and L3 carbohydrate structures shared by neural adhesion molecules

1987 • 115 citations

P0 promoter directs expression of reporter and toxin genes to schwann cells of transgenic mice

1992 • 110 citations

Cell Type‐specific Effects of the Neural Adhesion Molecules L1 and N‐CAM on Diverse Second Messenger Systems

1992 • 106 citations

The PO glycoprotein of peripheral nerve myelin

1980 • 104 citations

Immunocytological localization of the major peripheral nervous system glycoprotein P0 and the L2/HNK-1 and L3 carbohydrate structures in developing and adult mouse sciatic nerve

1988 • 87 citations

Molecular specificity of L2 monoclonal antibodies that bind to carbohydrate determinants of neural cell adhesion molecules and their resemblance to other monoclonal antibodies recognizing the myelin-associated glycoprotein

1986 • 80 citations

The novel carbohydrate epitope L3 is shared by some neural cell adhesion molecules.

1987 • 74 citations

Manipulating the Genome by Homologous Recombination in Embryonic Stem Cells

1992 • 56 citations

Two Monoclonal Antibodies Recognizing Carbohydrate Epitopes on Neural Adhesion Molecules Interfere with Cell Interactions

1990 • 51 citations

Complex expression pattern of tenascin during innervation of the posterior limb buds of the developing chicken

1991 • 50 citations

Expressing antisense Po RNA in Schwann cells perturbs myelination

1991 • 49 citations

DNA Sequence, genomic organization, and chromosomal localization of the mouse peripheral myelin protein zero gene: Identification of polymorphic alleles

1991 • 39 citations

Neuronal Receptors That Regulate Axon Growth

1990 • 36 citations

Immunochemical characterization of antibodies to the myelin proteolipid protein (PLP)

1988 • 21 citations

Phosphorylation-dependent regulation of axon fasciculation.

1991 • 19 citations

The gene encoding peripheral myelin protein zero is located on mouse chromosome 1

1990 • 18 citations