Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

1976 • 5,526 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

The cadherins: cell-cell adhesion molecules controlling animal morphogenesis

1988 • 1,626 citations

Neural Cell Adhesion Molecule: Structure, Immunoglobulin-Like Domains, Cell Surface Modulation, and Alternative RNA Splicing

1987 • 1,134 citations

Elementary properties and pharmacological sensitivities of calcium channels in mammalian peripheral neurons

1989 • 667 citations

Regulation of growth cone behavior by calcium

1991 • 597 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction

1987 • 485 citations

Role of Ca2+ channels in the ability of membrane depolarization to prevent neuronal death induced by trophic-factor deprivation: evidence that levels of internal Ca2+ determine nerve growth factor dependence of sympathetic ganglion cells.

1989 • 405 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro.

1988 • 326 citations

K-252a: a specific inhibitor of the action of nerve growth factor on PC 12 cells

1988 • 320 citations

Neurite outgrowth in response to transfected N-CAM changes during development and is modulated by polysialic acid

1990 • 299 citations

Studies of adhesion molecules mediating interactions between cells of peripheral nervous system indicate a major role for L1 in mediating sensory neuron growth on Schwann cells in culture.

1988 • 288 citations

Guidance of optic nerve fibres by N-cadherin adhesion molecules

1988 • 279 citations

The effect of fibroblast growth factor on PC12 cells

1985 • 270 citations

A threshold effect of the major isoforms of NCAM on neurite outgrowth

1990 • 260 citations

The effects of N-cadherin misexpression on morphogenesis in xenopus embryos

1990 • 242 citations

Neurite outgrowth on muscle cell surfaces involves extracellular matrix receptors as well as Ca2+-dependent and -independent cell adhesion molecules.

1987 • 233 citations

A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF

1990 • 205 citations

Down regulation of protein kinase C in neuronal cells: effects on neurotransmitter release

1987 • 204 citations

[15] cAMP analog antagonists of cAMP action

1988 • 184 citations

Response of sensory neurites and growth cones to patterned substrata of laminin and fibronectin in vitro

1987 • 182 citations

Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs

1991 • 178 citations

Calcium hotspots caused by L-channel clustering promote morphological changes in neuronal growth cones

1990 • 170 citations

Role of G Proteins in Calcium Channel Modulation

1990 • 153 citations

Enhanced myogenesis in NCAM-transfected mouse myoblasts

1990 • 141 citations

Cellular expression of liver and neural cell adhesion molecules after transfection with their cDNAs results in specific cell-cell binding.

1987 • 136 citations

The role of transcription-dependent priming in nerve growth factor promoted neurite outgrowth

1982 • 130 citations

The use of cell lines in neurobiology

1990 • 128 citations

Skeletal muscle neural cell adhesion molecule (N-CAM): changes in protein and mRNA species during myogenesis of muscle cell lines.

1987 • 124 citations

G Protein Modulation of Calcium Currents in Neurons

1990 • 123 citations

Extracellular matrix molecules and cell adhesion molecules induce neurites through different mechanisms.

1990 • 116 citations

The survival of early chick sympathetic neurons in vitro is dependent on a suitable substrate but independent of NGF

1989 • 103 citations

The action of nerve growth factor and dibutyryl adenosine cyclic 3':5'- monophosphate on rat pheochromocytoma reveals distinct stages in the mechanisms underlying neurite outgrowth

1981 • 101 citations

Neuronal process outgrowth of human sensory neurons on monolayers of cells transfected with cDNAs for five human N-CAM isoforms.

1989 • 96 citations

Nerve growth factor-induced changes in neural cell adhesion molecule (N-CAM) in PC12 cells.

1987 • 89 citations

The importance of both early and delayed responses in the biological actions of nerve growth factor

1984 • 88 citations

Structure and function of the gene for neural cell adhesion molecule

1991 • 87 citations

Muscarinic stimulation of calcium influx and norepinephrine release in PC12 cells.

1988 • 83 citations

N‐Cadherin Gene Maps to Human Chromosome 18 and Is Not Linked to the E‐Cadherin Gene

1990 • 79 citations

Comparison of the effects of NGF, activators of protein kinase C, and a calcium ionophore on the expression of Thy-1 and N-CAM in PC12 cell cultures.

1988 • 69 citations

Dependence of cytosolic calcium in differentiating rat pheochromocytoma cells on calcium channels and intracellular stores.

1991 • 68 citations

The neuronal growth cone as a specialized transduction system

1991 • 67 citations

Factors controlling the expression of the NGF receptor in PC12 cells

1988 • 64 citations

Neurite guidance molecules

1989 • 57 citations

Growth of sympathetic nerve fibers in culture does not require extracellular calcium

1989 • 54 citations

Inhibition of neuronal Ca2+ channel currents by the funnel web spider toxin omega-Aga-IA.

1990 • 46 citations

Intercellular adhesion mediated by human muscle neural cell adhesion molecule: effects of alternative exon use.

1989 • 35 citations

Increased Intracellular Cyclic AMP Differentially Modulates Nerve Growth Factor Induction of Three Neuronal Recognition Molecules Involved in Neurite Outgrowth

1989 • 29 citations

Control of Thy‐1 Glycoprotein Expression in Cultures of PC12 Cells

1987 • 20 citations

Cell-cell interactions modulate the responsiveness of PC12 cells to nerve growth factor

1987 • 11 citations

Two states of the L-type Ca2+ channel in PC12 cells: Different sensitivity to 1,4-dihydropyridines

1991 • 6 citations

Analysis of PC12 cell adhesion to muscle and non-muscle cells and components of the extracellular matrix

1988 • 4 citations