Neural cell adhesion molecules modulate tyrosine phosphorylation of tubulin in nerve growth cone membranes

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cadherin Cell Adhesion Receptors as a Morphogenetic Regulator

1991 • 3,314 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1991 • 2,028 citations

Vectors for selective expression of cloned DNAs by T7 RNA polymerase

1987 • 1,449 citations

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

1988 • 1,442 citations

DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA

1976 • 1,290 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

Tyrosine phosphorylation and tyrosine kinase activity of the trk proto-oncogene product induced by NGF

1991 • 1,049 citations

Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons

1992 • 895 citations

Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

1984 • 739 citations

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

1988 • 653 citations

Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src

1991 • 630 citations

Nerve growth factor, laminin, and fibronectin promote neurite growth in human fetal sensory ganglia cultures

1982 • 541 citations

L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum

1983 • 482 citations

Immunoelectron microscopic localization of neural cell adhesion molecules (L1, N-CAM, and MAG) and their shared carbohydrate epitope and myelin basic protein in developing sciatic nerve.

1986 • 482 citations

Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

1991 • 394 citations

Neural cell adhesion molecules influence second messenger systems

1989 • 387 citations

Neurones express high levels of a structurally modified, activated form of pp60c-src

1985 • 372 citations

Genetic analysis of a drosophila neural cell adhesion molecule: Interaction of fasciclin I and abelson tyrosine kinase mutations

1990 • 340 citations

Myelin-associated glycoprotein, a member of the L2/HNK-1 family of neural cell adhesion molecules, is involved in neuron-oligodendrocyte and oligodendrocyte-oligodendrocyte interaction.

1987 • 335 citations

Alterations in neural crest migration by a monoclonal antibody that affects cell adhesion.

1985 • 322 citations

The neural crest cell lineage problem: Neuropoiesis?

1989 • 315 citations

Neuronal pp60 ^{c- src} Contains a Six-Amino Acid Insertion Relative to Its Non-Neuronal Counterpart

1987 • 313 citations

Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic chicken brains.

1982 • 311 citations

The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions.

1990 • 305 citations

The 180-kD component of the neural cell adhesion molecule N-CAM is involved in cell-cell contacts and cytoskeleton-membrane interactions

1987 • 303 citations

pp60c-src is developmentally regulated in the neural retina

1984 • 299 citations

Neural Tissues Express High Levels of the Cellular src Gene Product pp60^c-src

1983 • 288 citations

Molecular cloning and primary structure of myelin-associated glycoprotein.

1987 • 284 citations

Guidance of optic nerve fibres by N-cadherin adhesion molecules

1988 • 279 citations

Assembly of microtubules at the tip of growing axons

1986 • 277 citations

Purified N-cadherin is a potent substrate for the rapid induction of neurite outgrowth.

1990 • 273 citations

Nerve growth cones isolated from fetal rat brain: Subcellular fractionation and characterization

1983 • 263 citations

Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src.

1986 • 257 citations

Drosophila abl tyrosine kinase in embryonic CNS axons: A role in axonogenesis is revealed through dosage-sensitive interactions with disabled

1989 • 240 citations

A polymer-dependent increase in phosphorylation of beta-tubulin accompanies differentiation of a mouse neuroblastoma cell line.

1985 • 237 citations

Immunohistological localization of the adhesion molecules L1, N‐CAM, and MAG in the developing and adult optic nerve of mice

1989 • 233 citations

Isolation and nucleotide sequence of mouse NCAM cDNA that codes for a Mr 79,000 polypeptide without a membrane-spanning region.

1987 • 231 citations

Ciliary and flagellar membranes

1990 • 230 citations

Immunoelectron microscopic localization of the neural cell adhesion molecules L1 and N-CAM during postnatal development of the mouse cerebellum.

1987 • 215 citations

c-src gene product in developing rat brain is enriched in nerve growth cone membranes.

1988 • 193 citations

Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function

1989 • 190 citations

Neural tissues express high levels of the cellular src gene product pp60c-src.

1983 • 179 citations

Neurite outgrowth in response to transfected N-CAM and N-cadherin reveals fundamental differences in neuronal responsiveness to CAMs

1991 • 178 citations

Functional cooperation between the neural adhesion molecules L1 and N-CAM is carbohydrate dependent.

1990 • 174 citations

Myristic acid is attached to the transforming protein of Rous sarcoma virus during or immediately after synthesis and is present in both soluble and membrane-bound forms of the protein.

1984 • 173 citations

The role of cell adhesion molecules in neurite outgrowth on Müller cells

1990 • 164 citations

Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein.

1985 • 163 citations

CD45, an integral membrane protein tyrosine phosphatase. Characterization of enzyme activity.

1990 • 163 citations

Two isozymes of the Na,K-ATPase have distinct antigenic determinants.

1985 • 150 citations

pp60c-src in the developing cerebellum.

1985 • 147 citations

Tubulin is phosphorylated at tyrosine by pp60c-src in nerve growth cone membranes.

1990 • 137 citations

Cell-substratum adhesion in chick neural retina depends upon protein-heparan sulfate interactions.

1985 • 136 citations

Cell Adhesion Molecules in Neural Development (Part 1 of 2)

1989 • 131 citations

Increased pp60c-src tyrosyl kinase activity in human neuroblastomas is associated with amino-terminal tyrosine phosphorylation of the src gene product.

1985 • 129 citations

Changes in neural cell adhesion molecule (NCAM) structure during vertebrate neural development.

1987 • 129 citations

Neuron-specific interactions with two neurite-promoting fragments of fibronectin

1985 • 123 citations

Binding Properties of the Neural Cell Adhesion Molecule to Different Components of the Extracellular Matrix

1989 • 115 citations

pp60c-src kinase is in chick and human embryonic tissues

1984 • 103 citations

Processing of p60v-src to its myristylated membrane-bound form.

1985 • 102 citations

Nerve growth cones isolated from fetal rat brain. IV. Preparation of a membrane subfraction and identification of a membrane glycoprotein expressed on sprouting neurons.

1985 • 95 citations

Regulated plasmalemmal expansion in nerve growth cones.

1991 • 87 citations

Expression and function of a putative cell surface receptor for fibronectin in hamster and human cell lines.

1986 • 81 citations

Influence of the composition of commercial sodium dodecyl sulfate preparations on the separation of α- and β-tubulin during polyacrylamide gel electrophoresis

1981 • 77 citations

Immunocytochemical localization of the neuron-specific form of the c- src gene product, pp60c-src(+), in rat brain

1990 • 76 citations

Estradiol stimulates cadherin expression in rat granulosa cells

1989 • 70 citations

A Protein Kinase Activity Is Associated with and Specifically Phosphorylates the Neural Cell Adhesion Molecule LI

1989 • 68 citations

Interactions of the neural cell adhesion molecule and the myelin-associated glycoprotein with collagen type I: involvement in fibrillogenesis.

1992 • 66 citations

Adhesion of neural cells to extracellular matrix constituents. Involvement of glycosaminoglycans and cell adhesion molecules

1988 • 54 citations

pp60^c‐src encoded by the proto‐oncogene c‐src is a product of sensory neurons

1986 • 41 citations

Membrane proteins of the nerve growth cone and their developmental regulation

1989 • 39 citations

Increased expression of pp60^c‐src protein‐tyrosine kinase during peripheral nerve regeneration

1991 • 39 citations

Developmental regulation of a cadherin during the differentiation of skeletal myoblasts

1990 • 35 citations

Proto-oncogenes in cell development

1992 • 32 citations

Protein tyrosine kinases in nervous system development

1992 • 22 citations

The founding of The Journal of Comparative Neurology

1991 • 21 citations

Tyrosine Phosphorylation of Membrane‐Associated Tubulin in Nerve Growth Cones Enriched in pp60 ^c‐src

2007 • 13 citations

Ciliary Membrane Tubulin

1990 • 11 citations