Impaired Th1 responses in mice deficient in Epstein‐Barr virus‐induced gene 3 and challenged with physiological doses of Leishmania major

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor.

1992 • 3,751 citations

CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity

2002 • 1,733 citations

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

2002 • 1,401 citations

The Regulation of Immunity to Leishmania Major

1995 • 1,265 citations

The immunology of susceptibility and resistance to Leishmania major in mice

2002 • 1,173 citations

WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27

2004 • 674 citations

The IL-27R (WSX-1) Is Required to Suppress T Cell Hyperactivity during Infection

2003 • 483 citations

WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection

2001 • 409 citations

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

2000 • 394 citations

A Natural Model ofLeishmania majorInfection Reveals a Prolonged “Silent” Phase of Parasite Amplification in the Skin Before the Onset of Lesion Formation and Immunity

2000 • 359 citations

CD8+ T Cells Are Required for Primary Immunity in C57BL/6 Mice Following Low-Dose, Intradermal Challenge withLeishmania major

2002 • 304 citations

Uptake of Leishmania major Amastigotes Results in Activation and Interleukin 12 Release from Murine Skin–derived Dendritic Cells: Implications for the Initiation of Anti-Leishmania Immunity

1998 • 284 citations

Novel IL-12 family members shed light on the orchestration of Th1 responses

2003 • 274 citations

WSX-1 Is Required for Resistance to Trypanosoma cruzi Infection by Regulation of Proinflammatory Cytokine Production

2003 • 264 citations

In the Absence of IL-12, CD4+ T Cell Responses to Intracellular Pathogens Fail to Default to a Th2 Pattern and Are Host Protective in an IL-10−/− Setting

2002 • 258 citations

The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity

2004 • 249 citations

Understanding the Pro- and Anti-Inflammatory Properties of IL-27

2004 • 227 citations

IL-12 Is Required to Maintain a Th1 Response DuringLeishmania majorInfection

2000 • 207 citations

A Subset of Liver NK T Cells Is Activated duringLeishmania donovaniInfection by CD1d-bound Lipophosphoglycan

2004 • 198 citations

Identification of genes specifically expressed in human activated and mature dendritic cells through serial analysis of gene expression

2000 • 193 citations

Disruption of T helper 2-immune responses in Epstein–Barr virus-induced gene 3-deficient mice

2002 • 176 citations

Interleukin 1α Promotes Th1 Differentiation and Inhibits Disease Progression in Leishmania major–susceptible BALB/c Mice

2003 • 152 citations

Dendritic Cell (DC)-Based Anti-Infective Strategies: DCs Engineered to Secrete IL-12 Are a Potent Vaccine in a Murine Model of an Intracellular Infection

1999 • 140 citations

Expression of IL‐27 in human Th1‐associated granulomatous diseases

2004 • 135 citations

Identification of genes specifically expressed in human activated and mature dendritic cells through serial analysis of gene expression

2000 • 135 citations

Leishmania major-infected murine Langerhans cell-like dendritic cells from susceptible mice release IL-12 after infection and vaccinate against experimental cutaneous Leishmaniasis

2000 • 134 citations

Antigen-pulsed epidermal Langerhans cells protect susceptible mice from infection with the intracellular parasiteLeishmania major

1998 • 113 citations

Cutting Edge: Early IL-4 Production Governs the Requirement for IL-27-WSX-1 Signaling in the Development of Protective Th1 Cytokine Responses following Leishmania major Infection

2004 • 98 citations

CD4+ T Cell Polarization in Mice Is Modulated by Strain-specific Major Histocompatibility Complex–independent Differences within Dendritic Cells

2003 • 95 citations

Hyperproduction of Proinflammatory Cytokines by WSX-1-Deficient NKT Cells in Concanavalin A-Induced Hepatitis

2004 • 87 citations

Interferon-β differentially regulates expression of the IL-12 family members p35, p40, p19 and EBI3 in activated human dendritic cells

2002 • 62 citations

WSX-1: A Key Role in Induction of Chronic Intestinal Nematode Infection

2004 • 56 citations