The IL-27 Receptor (WSX-1) Is an Inhibitor of Innate and Adaptive Elements of Type 2 Immunity

Interleukin-12 and the regulation of innate resistance and adaptive immunity

2003 • 3,689 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

The lineage decisions of helper T cells

2002 • 1,678 citations

<scp>gp</scp>130 AND THE INTERLEUKIN-6 FAMILY OF CYTOKINES

1997 • 1,468 citations

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

2002 • 1,401 citations

Cytokine Signaling in 2002

2002 • 1,089 citations

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

2002 • 985 citations

The IL-12 Family of Heterodimeric Cytokines

2003 • 889 citations

Helper T Cell Differentiation Is Controlled by the Cell Cycle

1998 • 862 citations

WSX-1 and Glycoprotein 130 Constitute a Signal-Transducing Receptor for IL-27

2004 • 674 citations

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

2003 • 534 citations

The IL-27R (WSX-1) Is Required to Suppress T Cell Hyperactivity during Infection

2003 • 483 citations

Reciprocal regulation of gastrointestinal homeostasis by SHP2 and STAT-mediated trefoil gene activation in gp130 mutant mice

2002 • 461 citations

IL-27 regulates IL-12 responsiveness of naïve CD4 ⁺ T cells through Stat1-dependent and -independent mechanisms

2003 • 456 citations

Cytokine-mediated regulation of chronic intestinal helminth infection.

1994 • 425 citations

WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection

2001 • 409 citations

Inhibition of Th1 Differentiation by IL-6 Is Mediated by SOCS1

2000 • 397 citations

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

2000 • 394 citations

STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: A critical role of STAT3 in innate immunity

2003 • 389 citations

A distinct role for interleukin-13 in Th2-cell-mediated immune responses

1998 • 380 citations

Systemic anaphylaxis in the mouse can be mediated largely through IgG1 and Fc gammaRIII. Assessment of the cardiopulmonary changes, mast cell degranulation, and death associated with active or IgE- or IgG1-dependent passive anaphylaxis.

1997 • 363 citations

SOCS-3 regulates onset and maintenance of TH2-mediated allergic responses

2003 • 356 citations

RELMβ/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract

2004 • 317 citations

IL-27 and IFN-αSignal via Stat1 and Stat3 and Induce T-Bet and IL-12Rβ2 in Naive T Cells

2003 • 313 citations

Epstein–Barr virus-induced gene 3 and the p35 subunit of interleukin 12 form a novel heterodimeric hematopoietin

1997 • 308 citations

Interferon α/β-mediated inhibition and promotion of interferon γ: STAT1 resolves a paradox

2000 • 293 citations

A Critical Role for IL-13 in Resistance to Intestinal Nematode Infection

1998 • 284 citations

Novel IL-12 family members shed light on the orchestration of Th1 responses

2003 • 274 citations

WSX-1 Is Required for Resistance to Trypanosoma cruzi Infection by Regulation of Proinflammatory Cytokine Production

2003 • 264 citations

Molecular Phylogeny within Type I Cytokines and Their Cognate Receptors

2003 • 260 citations

Suppressors of Cytokine Signaling Proteins Are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance

2002 • 243 citations

Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterine Implantation

2001 • 224 citations

Further Checkpoints in Th1 Development

2002 • 206 citations

Disruption of T helper 2-immune responses in Epstein–Barr virus-induced gene 3-deficient mice

2002 • 176 citations

Tumor Necrosis Factor α Is a Critical Component of Interleukin 13–Mediated Protective T Helper Cell Type 2 Responses during Helminth Infection

1999 • 145 citations

Cloning and Characterization of a Novel Class I Cytokine Receptor

1998 • 140 citations

Bacterial colonization leads to the colonic secretion of RELMβ/FIZZ2, a novel goblet cell-specific protein

2003 • 138 citations

Parasitic nematodes: molecular biology, biochemistry and immunology

2013 • 117 citations

Interleukin (Il)-18 Promotes the Development of Chronic Gastrointestinal Helminth Infection by Downregulating IL-13

2001 • 101 citations

Cutting Edge: Early IL-4 Production Governs the Requirement for IL-27-WSX-1 Signaling in the Development of Protective Th1 Cytokine Responses following Leishmania major Infection

2004 • 98 citations

Interleukin‐12 promotes a chronic intestinal nematode infection

1997 • 92 citations

Hyperproduction of Proinflammatory Cytokines by WSX-1-Deficient NKT Cells in Concanavalin A-Induced Hepatitis

2004 • 87 citations

Differential Requirement for NF-κB Family Members in Control of Helminth Infection and Intestinal Inflammation

2002 • 84 citations

A regulatory role for suppressor of cytokine signaling-1 in Th polarization in vivo

2002 • 77 citations

Mast cell heterogeneity in the gastrointestinal tract: variable expression of mouse mast cell protease-1 (mMCP-1) in intraepithelial mucosal mast cells in nematode-infected and normal BALB/c mice.

1997 • 73 citations

WSX-1: A Key Role in Induction of Chronic Intestinal Nematode Infection

2004 • 56 citations

Role of STAT6 in IgE Receptor/FcεRI-Mediated Late Phase Allergic Responses of Mast Cells

2002 • 39 citations

T helper cell cytokine responses during intestinal nematode infection: induction, regulation and effector function.

2001 • 19 citations