WSX-1 Is Required for Resistance to Trypanosoma cruzi Infection by Regulation of Proinflammatory Cytokine Production

Interleukin-10 and the Interleukin-10 Receptor

2001 • 6,422 citations

IL-27, a Heterodimeric Cytokine Composed of EBI3 and p28 Protein, Induces Proliferation of Naive CD4+ T Cells

2002 • 1,401 citations

A Receptor for the Heterodimeric Cytokine IL-23 Is Composed of IL-12Rβ1 and a Novel Cytokine Receptor Subunit, IL-23R

2002 • 1,238 citations

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response.

1993 • 738 citations

Parasite-induced IL-12 stimulates early IFN-gamma synthesis and resistance during acute infection with Toxoplasma gondii.

1994 • 729 citations

IL-10 inhibits parasite killing and nitrogen oxide production by IFN-gamma-activated macrophages.

1992 • 709 citations

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

2003 • 534 citations

The IL-27R (WSX-1) Is Required to Suppress T Cell Hyperactivity during Infection

2003 • 483 citations

WSX-1 Is Required for the Initiation of Th1 Responses and Resistance to L. major Infection

2001 • 409 citations

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

2000 • 394 citations

Modulation of Macrophage Function by Transforming Growth Factor ?, Interleukin-4, and Interleukin-10

1993 • 393 citations

Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection.

1992 • 364 citations

IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi.

1997 • 350 citations

The Transcription Factor NF-ATc1 Regulates Lymphocyte Proliferation and Th2 Cytokine Production

1998 • 340 citations

Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes

1996 • 287 citations

Importance of Kupffer Cells for T-Cell-Dependent Liver Injury in Mice

2000 • 282 citations

Novel IL-12 family members shed light on the orchestration of Th1 responses

2003 • 274 citations

Regulation of Trypanosoma cruzi infection in mice by gamma interferon and interleukin 10: role of NK cells

1996 • 270 citations

In vivo administration of recombinant IFN-gamma induces macrophage activation, and prevents acute disease, immune suppression, and death in experimental Trypanosoma cruzi infections.

1988 • 256 citations

Depletion of CD8+ T cells increases susceptibility and reverses vaccine-induced immunity in mice infected with Trypanosoma cruzi.

1990 • 238 citations

Pleiotropy and redundancy: T cell-derived lymphokines in the immune response

1989 • 228 citations

Resistance against Trypanosoma cruzi associated to anti-living trypomastigote antibodies.

1982 • 217 citations

Glycosylphosphatidylinositol-anchored mucin-like glycoproteins isolated from Trypanosoma cruzi trypomastigotes initiate the synthesis of proinflammatory cytokines by macrophages.

1997 • 206 citations

CYTOKINE EXPRESSION IN THREE MOUSE MODELS OF EXPERIMENTAL HEPATITIS

2002 • 199 citations

Trypanosoma cruzi:IL-10, TNF, IFN-γ, and IL-12 Regulate Innate and Acquired Immunity to Infection

1996 • 189 citations

Regulatory Role of T Cells Producing both Interferon γ and Interleukin 10 in Persistent Infection

2001 • 171 citations

Cloning and Characterization of a Novel Class I Cytokine Receptor

1998 • 140 citations

Tumor Necrosis Factor Alpha-Mediated Toxic Shock inTrypanosoma cruzi-Infected Interleukin 10-Deficient Mice

2000 • 138 citations

Signaling mechanisms through cytokine receptors that share signal transducing receptor components

1995 • 105 citations

Interferon γ Derived from CD4+ T Cells Is Sufficient to Mediate T Helper Cell Type 1 Development

1998 • 92 citations

Role of T Helper/Inducer Cells as well as Natural Killer Cells in Resistance to Trypanosoma cruzi Infection

1988 • 84 citations

Experimental hepatitis and role of cytokines.

1997 • 78 citations

Modulation of Chagasic Cardiomyopathy by Interleukin-4

2001 • 77 citations

IL‐6, IFN‐γ and TNF‐α production by liver‐associated T cells and acute liver injury in rats administered concanavalin A

1998 • 68 citations

Augmentation of the CD8+ T cell response by IFN-gamma in IL-12-deficient mice during Toxoplasma gondii infection.

1999 • 66 citations

Augmentation of the CD8+ T Cell Response by IFN-γ in IL-12-Deficient Mice DuringToxoplasma gondiiInfection

1999 • 59 citations

Effect of anti-γ-interferon and anti-interleukin-4 administration on the resistance of mice against infection with reticulotropic and myotropic strains of Trypanosoma cruzi

1993 • 48 citations

Effects of Interleukin-4 Deprivation and Treatment on Resistance toTrypanosoma cruzi

2000 • 33 citations

IL-4 reduces resistance of mice to Trypanosoma cruzi infection

2001 • 28 citations

Role of IL–27/WSX–1 signaling for induction of T–bet through activation of STAT1 during initial Th1 commitment

2004 • 24 citations

Analysis of the role of CD4+ T-cells during murine cytomegalovirus infection in different strains of mice

1995 • 18 citations