Proliferating cell nuclear antigen (PCNA): a dancer with many partners

RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO

2002 • 2,139 citations

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1994 • 1,669 citations

The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η

1999 • 1,273 citations

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1992 • 1,023 citations

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

1994 • 899 citations

Human DNA-(Cytosine-5) Methyltransferase-PCNA Complex as a Target for p21 ^WAF1

1997 • 895 citations

Mammalian DNA nucleotide excision repair reconstituted with purified protein components

1995 • 833 citations

Proliferating cell nuclear antigen is required for DNA excision repair

1992 • 809 citations

Structure of the C-Terminal Region of p21WAF1/CIP1 Complexed with Human PCNA

1996 • 790 citations

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1)

1997 • 779 citations

Error-Prone Repair DNA Polymerases in Prokaryotes and Eukaryotes

2002 • 730 citations

Eukaryotic DNA Polymerases

2002 • 682 citations

Replication-Dependent Marking of DNA by PCNA Facilitates CAF-1-Coupled Inheritance of Chromatin

1999 • 674 citations

Requirement for PCNA in DNA Mismatch Repair at a Step Preceding DNA Resynthesis

1996 • 569 citations

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA

1995 • 561 citations

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1995 • 552 citations

Visualization of replication factories attached to a nucleoskeleton

1993 • 472 citations

Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery

1999 • 444 citations

The puzzle of PCNA's many partners

2000 • 414 citations

Reconstitution of complete SV40 DNA replication with purified replication factors.

1994 • 403 citations

The puzzle of PCNA's many partners

2000 • 380 citations

Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes.

1993 • 362 citations

RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes

2001 • 335 citations

A CAF-1–PCNA-Mediated Chromatin Assembly Pathway Triggered by Sensing DNA Damage

2000 • 327 citations

PCNA connects DNA replication to epigenetic inheritance in yeast

2000 • 302 citations

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

1994 • 268 citations

Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

2001 • 258 citations

Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen

1998 • 251 citations

The Werner Syndrome Gene Product Co-purifies with the DNA Replication Complex and Interacts with PCNA and Topoisomerase I

1999 • 249 citations

hMSH3 and hMSH6 interact with PCNA and colocalize with it to replication foci

2001 • 248 citations

Proliferating cell nuclear antigen: More than a clamp for DNA polymerases

1997 • 248 citations

An interaction between DNA ligase I and proliferating cell nuclear antigen: Implications for Okazaki fragment synthesis and joining

1997 • 242 citations

Okazaki Fragment Maturation in Yeast

2003 • 236 citations

The DNA Repair Endonuclease XPG Binds to Proliferating Cell Nuclear Antigen (PCNA) and Shares Sequence Elements with the PCNA-binding Regions of FEN-1 and Cyclin-dependent Kinase Inhibitor p21

1997 • 236 citations

Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex

2000 • 232 citations

Physical and Functional Interactions of Human DNA Polymerase η with PCNA

2001 • 229 citations

Purification of PCNA as a nucleotide excision repair protein

1992 • 228 citations

Different DNA Polymerases Are Involved in the Short- and Long-Patch Base Excision Repair in Mammalian Cells

1998 • 225 citations

A Heterotrimeric PCNA in the Hyperthermophilic Archaeon Sulfolobus solfataricus

2003 • 223 citations

Functional Interaction of Proliferating Cell Nuclear Antigen with MSH2-MSH6 and MSH2-MSH3 Complexes

2000 • 223 citations

DNA Polymerase Clamp Shows Little Turnover at Established Replication Sites but Sequential De Novo Assembly at Adjacent Origin Clusters

2002 • 212 citations

Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme

1999 • 211 citations

Interaction between PCNA and DNA ligase I is critical for joining of Okazaki fragments and long-patch base-excision repair

2000 • 207 citations

DNA ligaseI is recruited to sites of DNA replication by an interaction with proliferating cell nuclear antigen: identification of a common targeting mechanism for the assembly of replication factories

1998 • 206 citations

Interactions between the Werner Syndrome Helicase and DNA Polymerase δ Specifically Facilitate Copying of Tetraplex and Hairpin Structures of the d(CGG) Trinucleotide Repeat Sequence

2001 • 205 citations

Long Patch Base Excision Repair with Purified Human Proteins

1999 • 198 citations

Localization of DNA polymerases η and ι to the replication machinery is tightly co-ordinated in human cells

2002 • 189 citations

Functional interaction between the Werner Syndrome protein and DNA polymerase δ

2000 • 187 citations

Targeting of human DNA polymerase ι to the replication machinery via interaction with PCNA

2001 • 184 citations

Reconstitution of Proliferating Cell Nuclear Antigen-dependent Repair of Apurinic/Apyrimidinic Sites with Purified Human Proteins

1999 • 177 citations

Structural and functional similarities of prokaryotic and eukaryotic DNA polymerase sliding clamps

1995 • 173 citations

Stimulation of DNA Synthesis Activity of Human DNA Polymerase κ by PCNA

2002 • 173 citations

Characterization of the Enzymatic Properties of the Yeast Dna2 Helicase/Endonuclease Suggests a New Model for Okazaki Fragment Processing

2000 • 172 citations

Replication factories and nuclear bodies: the ultrastructural characterization of replication sites during the cell cycle

1994 • 168 citations

Proliferating Cell Nuclear Antigen Facilitates Excision in Long-patch Base Excision Repair

1999 • 168 citations

Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis

2001 • 167 citations

Mechanism Whereby Proliferating Cell Nuclear Antigen Stimulates Flap Endonuclease 1

2000 • 163 citations

Mutations in Yeast Proliferating Cell Nuclear Antigen Define Distinct Sites for Interaction with DNA Polymerase δ and DNA Polymerase ε

1997 • 162 citations

Two modes of FEN1 binding to PCNA regulated by DNA

2000 • 160 citations

ATP Utilization by Yeast Replication Factor C

2001 • 156 citations

Homologous regions of Fen1 and p21Cip1 compete for binding to the same site on PCNA: a potential mechanism to co-ordinate DNA replication and repair

1997 • 155 citations

UV-induced binding of ING1 to PCNA regulates the induction of apoptosis

2001 • 153 citations

Interaction of Human AP Endonuclease 1 with Flap Endonuclease 1 and Proliferating Cell Nuclear Antigen Involved in Long-Patch Base Excision Repair

2001 • 147 citations

Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage

1996 • 144 citations

Okazaki Fragment Maturation in Yeast

2003 • 139 citations

Characterization of MyD118, Gadd45, and Proliferating Cell Nuclear Antigen (PCNA) Interacting Domains

2000 • 130 citations

PCNA clamp facilitates action of DNA cytosine methyltransferase 1 on hemimethylated DNA

2002 • 127 citations

Mechanism of Inhibition of Proliferating Cell Nuclear Antigen-Dependent DNA Synthesis by the Cyclin-Dependent Kinase Inhibitor p21

1995 • 126 citations

Direct Interaction between Mammalian DNA Polymerase β and Proliferating Cell Nuclear Antigen

2002 • 126 citations

Okazaki fragment processing: Modulation of the strand displacement activity of DNA polymerase δ by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1

2001 • 118 citations

A Direct Interaction between Proliferating Cell Nuclear Antigen (PCNA) and Cdk2 Targets PCNA-interacting Proteins for Phosphorylation

2000 • 118 citations

Transfer of the MSH2·MSH6 Complex from Proliferating Cell Nuclear Antigen to Mispaired Bases in DNA

2002 • 109 citations

Mediation of Proliferating Cell Nuclear Antigen (PCNA)-dependent DNA Replication through a Conserved p21Cip1-like PCNA-binding Motif Present in the Third Subunit of Human DNA Polymerase δ

2001 • 107 citations

Molecular mechanism of PCNA-dependent base excision repair

2001 • 105 citations

Characterisation of the interaction between PCNA and Gadd45.

1995 • 103 citations

Human DNA Polymerase λ Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA Synthesis

2002 • 102 citations

A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells.

1996 • 93 citations

Identification of DNA replication and cell cycle proteins that interact with PCNA

1997 • 93 citations

A Novel PCNA-Binding Motif Identified by the Panning of a Random Peptide Display Library

2001 • 90 citations

Direct Interaction of Proliferating Cell Nuclear Antigen with the p125 Catalytic Subunit of Mammalian DNA Polymerase δ

1999 • 88 citations

Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.

1996 • 87 citations

Properties and functions of human uracil-DNA glycosylase from the UNG gene

2001 • 85 citations

DNA polymerase switching: I. Replication factor C displaces DNA polymerase α prior to PCNA loading

2000 • 85 citations

A Proteomics Approach to Identify Proliferating Cell Nuclear Antigen (PCNA)-binding Proteins in Human Cell Lysates

2002 • 84 citations

A Quantitative Study of the in Vitro Binding of the C-Terminal Domain of p21 to PCNA: Affinity, Stoichiometry, and Thermodynamics

2000 • 84 citations

Detection of Nucleotide Excision Repair Incisions in Human Fibroblasts by Immunostaining for PCNA

1995 • 81 citations

Resistance of human nucleotide excision repair synthesis in vitro to p21Cdn1

1998 • 73 citations

The replication factory targeting sequence/PCNA-binding site is required in G1 to control the phosphorylation status of DNA ligase I

1999 • 72 citations

The small subunit is required for functional interaction of DNA polymerase delta with the proliferating cell nuclear antigen

1997 • 67 citations

The solution structure of functionally active human proliferating cell nuclear antigen determined by small-angle neutron scattering 1 1Edited by M. F. Moody

1998 • 62 citations

Stimulation of 3′→5′ Exonuclease and 3′-Phosphodiesterase Activities of Yeast Apn2 by Proliferating Cell Nuclear Antigen

2002 • 61 citations

p21^CIP1 Controls Proliferating Cell Nuclear Antigen Level in Adult Cardiomyocytes

2003 • 55 citations

Nuclear organization: Uniting replication foci, chromatin domains and chromosome structure

1995 • 50 citations

Co-localization of chicken DNA topoisomerase IIα, but not β, with sites of DNA replication and possible involvement of a C-terminal region of α through its binding to PCNA

2001 • 47 citations

In Vivo Reconstitution of Saccharomyces cerevisiae DNA Polymerase ε in Insect Cells

2002 • 46 citations

DNA Replication Machinery: Functional Characterization of a Complex Containing DNA Polymerase α, DNA Polymerase δ, and Replication Factor C Suggests an Asymmetric DNA Polymerase Dimer

1996 • 45 citations

DNA polymerase .epsilon. interacts with proliferating cell nuclear antigen in primer recognition and elongation

1995 • 40 citations

Two Immunologically Distinct Human DNA Polymerase α-Primase Subpopulations Are Involved in Cellular DNA Replication

2001 • 37 citations

DNA Replication: A familiar ring to DNA polymerase processivity

1995 • 37 citations

Interaction studies between the p21Cip1/Waf1 cyclin‐dependent kinase inhibitor and proliferating cell nuclear antigen (PCNA) by surface plasmo resonance

1996 • 28 citations

Effect of XPA gene mutations on UV-induced immunostaining of PCNA in fibroblasts from xeroderma pigmentosum group A patients

1996 • 16 citations

The amino terminus of Cdk2 binds p21.

1996 • 5 citations