ATP Utilization by Yeast Replication Factor C

Distantly related sequences in the alpha- and beta-subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold.

1982 • 5,284 citations

The P-loop — a common motif in ATP- and GTP-binding proteins

1990 • 2,029 citations

AAA⁺: A Class of Chaperone-Like ATPases Associated with the Assembly, Operation, and Disassembly of Protein Complexes

1999 • 1,793 citations

PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae

1996 • 852 citations

THE DNA REPLICATION FORK IN EUKARYOTIC CELLS

1998 • 815 citations

Recombinant replication protein A: expression, complex formation, and functional characterization

1994 • 579 citations

Requirement for PCNA in DNA Mismatch Repair at a Step Preceding DNA Resynthesis

1996 • 569 citations

ATP-binding site of adenylate kinase: mechanistic implications of its homology with ras-encoded p21, F1-ATPase, and other nucleotide-binding proteins.

1986 • 538 citations

The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast.

1994 • 502 citations

An auxiliary protein for DNA polymerase-delta from fetal calf thymus.

1986 • 500 citations

Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin

1990 • 430 citations

The functions and consensus motifs of nine types of peptide segments that form different types of nucleotide‐binding sites

1994 • 388 citations

Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins

1991 • 380 citations

Smart machines at the DNA replication fork

1994 • 312 citations

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.

1994 • 299 citations

Binding properties of replication protein A from human and yeast cells.

1992 • 292 citations

Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

1995 • 276 citations

Dpb11, which interacts with DNA polymerase II(epsilon) in Saccharomyces cerevisiae, has a dual role in S-phase progression and at a cell cycle checkpoint.

1995 • 275 citations

Proliferating cell nuclear antigen-dependent abasic site repair in Xenopus laevis oocytes: an alternative pathway of base excision DNA repair.

1994 • 268 citations

Saccharomyces cerevisiae replication factor C. II. Formation and activity of complexes with the proliferating cell nuclear antigen and with DNA polymerases delta and epsilon.

1991 • 265 citations

Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis

1991 • 263 citations

Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4.

1990 • 261 citations

Studies on the activator 1 protein complex, an accessory factor for proliferating cell nuclear antigen-dependent DNA polymerase delta.

1991 • 254 citations

Characterization of the Five Replication Factor C Genes of Saccharomyces cerevisiae

1995 • 248 citations

Crystal Structure of the δ′ Subunit of the Clamp-Loader Complex of E. coli DNA Polymerase III

1997 • 248 citations

The internal workings of a DNA polymerase clamp-loading machine

1999 • 217 citations

Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme

1999 • 211 citations

A Mutational Analysis of the Yeast Proliferating Cell Nuclear Antigen Indicates Distinct Roles in DNA Replication and DNA Repair

1995 • 209 citations

Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro.

1989 • 209 citations

Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex.

1992 • 209 citations

A novel Rad24 checkpoint protein complex closely related to replication factor C

2000 • 208 citations

Fission yeast rad17: a homologue of budding yeast RAD24 that shares regions of sequence similarity with DNA polymerase accessory proteins.

1995 • 207 citations

Mechanism of elongation of primed DNA by DNA polymerase delta, proliferating cell nuclear antigen, and activator 1.

1990 • 205 citations

Biochemical Analysis of the Intrinsic Mcm4-Mcm6-Mcm7 DNA Helicase Activity

1999 • 205 citations

Evidence for Involvement of Yeast Proliferating Cell Nuclear Antigen in DNA Mismatch Repair

1996 • 200 citations

RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae.

1996 • 168 citations

Reliable determination of binding affinity and kinetics using surface plasmon resonance biosensors

1997 • 167 citations

DNA damage checkpoint in budding yeast

1998 • 162 citations

Two modes of FEN1 binding to PCNA regulated by DNA

2000 • 160 citations

The yeast analog of mammalian cyclin/proliferating-cell nuclear antigen interacts with mammalian DNA polymerase delta.

1988 • 155 citations

Lysine 71 of the Chaperone Protein Hsc70 Is Essential for ATP Hydrolysis

1996 • 134 citations

DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae

1999 • 130 citations

Saccharomyces cerevisiae replication factor C. I. Purification and characterization of its ATPase activity.

1991 • 128 citations

Isolation of crt mutants constitutive for transcription of the DNA damage inducible gene RNR3 in Saccharomyces cerevisiae.

1992 • 127 citations

Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro

2000 • 125 citations

Deletion Analysis of the Large Subunit p140 in Human Replication Factor C Reveals Regions Required for Complex Formation and Replication Activities

1997 • 119 citations

ATP Utilization by Yeast Replication Factor C

2001 • 114 citations

ATP-independent loading of the proliferating cell nuclear antigen requires DNA ends.

1993 • 106 citations

Requirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair.

1996 • 104 citations

Overproduction in Escherichia coli and Characterization of Yeast Replication Factor C Lacking the Ligase Homology Domain

2000 • 103 citations

Specific DNA Replication Mutations Affect Telomere Length in Saccharomyces cerevisiae

1996 • 101 citations

Mammalian DNA Polymerase Auxiliary Proteins: Analysis of Replication Factor C-Catalyzed Proliferating Cell Nuclear Antigen Loading onto Circular Double-Stranded DNA

1995 • 98 citations

Rfc5, a small subunit of replication factor C complex, couples DNA replication and mitosis in budding yeast.

1996 • 95 citations

A conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cells.

1996 • 93 citations

Role of the ATP-Binding Domain of the Human Papillomavirus Type 11 E1 Helicase in E2-Dependent Binding to the Origin

1999 • 91 citations

Rfc5, a Replication Factor C Component, Is Required for Regulation of Rad53 Protein Kinase in the Yeast Checkpoint Pathway

1997 • 91 citations

cDNAs encoding the large subunit of human replication factor C.

1993 • 88 citations

DNA polymerase switching: I. Replication factor C displaces DNA polymerase α prior to PCNA loading

2000 • 85 citations

Rfc5, in Cooperation with Rad24, Controls DNA Damage Checkpoints throughout the Cell Cycle in Saccharomyces cerevisiae

2000 • 85 citations

Functional and Physical Interaction between Rad24 and Rfc5 in the Yeast Checkpoint Pathways

1998 • 85 citations

Cyclin-Dependent Kinase Inhibitor p21 Modulates the DNA Primer-Template Recognition Complex

1998 • 81 citations

Replication Factor C Interacts with the C-terminal Side of Proliferating Cell Nuclear Antigen

1997 • 80 citations

Both ATPase sites of Escherichia coli UvrA have functional roles in nucleotide excision repair

1991 • 78 citations

Overproduction and Affinity Purification of Saccharomyces cerevisiae Replication Factor C

1997 • 75 citations

Replication Factor C Disengages from Proliferating Cell Nuclear Antigen (PCNA) upon Sliding Clamp Formation, and PCNA Itself Tethers DNA Polymerase δ to DNA

1998 • 75 citations

Overexpression of Multisubunit Replication Factors in Yeast

1999 • 74 citations

The RFC2 Gene, Encoding the Third-Largest Subunit of the Replication Factor C Complex, Is Required for an S-Phase Checkpoint in Saccharomyces cerevisiae

1998 • 73 citations

A Complex Consisting of Human Replication Factor C p40, p37, and p36 Subunits Is a DNA-dependent ATPase and an Intermediate in the Assembly of the Holoenzyme

1997 • 71 citations

Replication Factor C3 ofSchizosaccharomyces pombe, a Small Subunit of Replication Factor C Complex, Plays a Role in Both Replication and Damage Checkpoints

1999 • 71 citations

Directed mutations of the strongly conserved lysine 155 in the catalytic nucleotide-binding domain of beta-subunit of F1-ATPase from Escherichia coli.

1988 • 71 citations

Division of labor---sequential ATP hydrolysis drives assembly of a DNA polymerase sliding clamp around DNA

1999 • 69 citations

The subunits of activator 1 (replication factor C) carry out multiple functions essential for proliferating-cell nuclear antigen-dependent DNA synthesis.

1993 • 67 citations

DNA polymerase switching: II. Replication factor C abrogates primer synthesis by DNA polymerase α at a critical length

2000 • 65 citations

ATP Utilization by Yeast Replication Factor C

2001 • 65 citations

Proliferating cell nuclear antigen (pol30) mutations suppress cdc44 mutations and identify potential regions of interaction between the two encoded proteins.

1994 • 64 citations

Molecular cloning and expression of the Saccharomyces cerevisiae RFC3 gene, an essential component of replication factor C.

1994 • 63 citations

Functional Characterization of Residues in the P-loop Motif of the RecA Protein ATP Binding Site

1994 • 63 citations

The Large Subunit of Replication Factor C (Rfclp/Cdc44p) Is Required for DNA Replication and DNA Repair in Saccharomyces cerevisiae

1996 • 62 citations

A Model for Escherichia coli DNA Polymerase III Holoenzyme Assembly at Primer/Template Ends

2000 • 62 citations

CDC44: a putative nucleotide-binding protein required for cell cycle progression that has homology to subunits of replication factor C.

1994 • 59 citations

Selection by genetic transformation of a Saccharomyces cerevisiae mutant defective for the nuclear uracil-DNA-glycosylase

1986 • 58 citations

The Essential Role of Saccharomyces cerevisiae CDC6 Nucleotide-binding Site in Cell Growth, DNA Synthesis, and Orc1 Association

1999 • 57 citations

Identification of Regions within the Four Small Subunits of Human Replication Factor C Required for Complex Formation and DNA Replication

1997 • 57 citations

Role of Walker Motif A of RuvB Protein in Promoting Branch Migration of Holliday Junctions

1999 • 57 citations

Assembly of a Chromosomal Replication Machine: Two DNA Polymerases, a Clamp Loader, and Sliding Clamps in One Holoenzyme Particle.

1995 • 54 citations

ATP hydrolysis catalyzed by human replication factor C requires participation of multiple subunits

1998 • 53 citations

Assembly of DNA polymerase 6 and e holoenzymes depends on the geometry of the DNA template

1994 • 53 citations

Identification of a Residue Involved in Transition-State Stabilization in the ATPase Reaction of DNA Gyrase

1998 • 48 citations

CHL12, a gene essential for the fidelity of chromosome transmission in the yeast Saccharomyces cerevisiae.

1994 • 48 citations

Functional Interactions among the Subunits of Replication Factor C Potentiate and Modulate Its ATPase Activity

1998 • 46 citations

TheRFC2gene encoding a subunit of replication factor C ofSaccharomyces cerevisiae

1994 • 46 citations

Dissecting the Order of Bacteriophage T4 DNA Polymerase Holoenzyme Assembly

1998 • 44 citations

Site-directed Mutational Analysis for the ATP Binding of DnaA Protein

1998 • 42 citations

Cloning and characterization of the essential Saccharomyces cerevisiae RFC4 gene encoding the 37-kDa subunit of replication factor C.

1994 • 37 citations

DNA Structure Requirements for the Escherichia coliγ Complex Clamp Loader and DNA Polymerase III Holoenzyme

2000 • 36 citations

ATP Utilization by Yeast Replication Factor C

2001 • 35 citations

A key role for replication factor C in DNA replication checkpoint function in fission yeast

1999 • 35 citations

The influence of ATP on sugar uptake mediated by the constitutive glucose carrier of Saccharomyces cerevisiae

1988 • 33 citations

Active Site Mutants of Escherichia coli Dethiobiotin Synthetase: Effects of Mutations on Enzyme Catalytic and Structural Properties

1997 • 31 citations

Fluorescence Monitoring of T4 Polymerase Holoenzyme Accessory Protein Interactions During Loading of the Sliding Clamp onto the Template–Primer Junction

1996 • 31 citations

DNA recognition properties of the N-terminal DNA binding domain within the large subunit of replication factor C

1998 • 31 citations

Identification of the fifth subunit osSaccharomyces cerevisiaeReplication Factor C

1995 • 24 citations