Multidrug ABC transporters from bacteria to man: an emerging hypothesis for the universality of molecular mechanism and function

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

ABC Transporters: From Microorganisms to Man

1992 • 3,956 citations

The complete genome sequence of the Gram-positive bacterium Bacillus subtilis

1997 • 3,613 citations

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

1990 • 1,149 citations

Mutation of the Stargardt Disease Gene ( ABCR ) in Age-Related Macular Degeneration

1997 • 861 citations

The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein

1989 • 604 citations

GENETIC ANALYSIS OF THE MULTIDRUG TRANSPORTER

1995 • 469 citations

Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells.

1989 • 443 citations

Transport Protein Genes in the Murine MHC: Possible Implications for Antigen Processing

1990 • 438 citations

The 70-kDa peroxisomal membrane protein is a member of the Mdr (P-glycoprotein)-related ATP-binding protein superfamily.

1990 • 395 citations

Photosensitized labeling of a functional multidrug transporter in living drug-resistant tumor cells.

1990 • 386 citations

TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

1993 • 365 citations

Structure of the Multidrug Resistance P-glycoprotein to 2.5 nm Resolution Determined by Electron Microscopy and Image Analysis

1997 • 341 citations

DNA sequence of the white locus of Drosophila melanogaster

1984 • 282 citations

Multidrug resistance mediated by a bacterial homolog of the human multidrug transporter MDR1.

1996 • 275 citations

The gene responsible for adrenoleukodystrophy encodes a peroxisomal membrane protein

1994 • 262 citations

A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene

1998 • 234 citations

Mutations in the 70K peroxisomal membrane protein gene in Zellweger syndrome

1992 • 228 citations

The brown protein of Drosophila melanogaster is similar to the white protein and to components of active transport complexes.

1988 • 224 citations

A close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression pattern.

1996 • 221 citations

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

1996 • 194 citations

A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters.

1996 • 155 citations

Cloning and characterization of the scarlet gene of Drosophila melanogaster.

1989 • 126 citations

Sequence of a cDNA from theDrosophila melanogaster whitegene

1990 • 63 citations

The Minimum Functional Unit of Human P-glycoprotein Appears to be a Monomer

1996 • 55 citations

Heterologous expression systems for P-glycoprotein:E. coli, yeast, and baculovirus

1995 • 46 citations

Analysis of a single-domain P-glycoprotein-like gene in the early-diverging protist Trichomonas vaginalis

1994 • 36 citations

Major histocompatibility complex-linked transport proteins and antigen processing

1992 • 29 citations

The 70 kDa peroxisomal membrane protein: an ATP-binding cassette transporter protein involved in peroxisome biogenesis

1993 • 25 citations