Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3

Dendritic cells and the control of immunity

1998 • 14,345 citations

Positive and Negative Selection of T Cells

2003 • 1,547 citations

Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

2002 • 1,019 citations

T-cell development and the CD4–CD8 lineage decision

2002 • 738 citations

Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

2002 • 712 citations

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

1994 • 560 citations

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

1998 • 468 citations

ETS Gene Er81 Controls the Formation of Functional Connections between Group Ia Sensory Afferents and Motor Neurons

2000 • 458 citations

The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons

2002 • 424 citations

Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance

2003 • 420 citations

A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

1994 • 418 citations

Groucho/TLE family proteins and transcriptional repression

2000 • 412 citations

Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

2003 • 380 citations

Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase.

1998 • 379 citations

Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

2002 • 301 citations

Runx3 regulates mouse TGF-β-mediated dendritic cell function and its absence results in airway inflammation

2004 • 281 citations

Structure and regulated expression of mammalian RUNX genes

2004 • 276 citations

Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes

2002 • 244 citations

Collaborative spirit of histone deacetylases in regulating chromatin structure and gene expression

2003 • 240 citations

Core-binding factors in hematopoiesis and immune function

2004 • 236 citations

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis

2001 • 181 citations

The RUNX3 gene – sequence, structure and regulated expression

2001 • 177 citations

Role of RUNX family members in transcriptional repression and gene silencing

2004 • 173 citations

Epigenetic silencing of CD4 in T cells committed to the cytotoxic lineage

2001 • 172 citations

Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

2004 • 166 citations

Dual Functions of Runx Proteins for Reactivating CD8 and Silencing CD4 at the Commitment Process into CD8 Thymocytes

2005 • 160 citations

A transcriptional silencer controls the developmental expression of the CD4 gene.

1994 • 156 citations

Sequential Roles of Brg, the ATPase Subunit of BAF Chromatin Remodeling Complexes, in Thymocyte Development

2003 • 155 citations

The Runx genes: lineage-specific oncogenes and tumor suppressors

2004 • 153 citations

The Groucho/Transducin-like Enhancer of split Transcriptional Repressors Interact with the Genetically Defined Amino-terminal Silencing Domain of Histone H3

1997 • 149 citations

Toward the Neural Basis of Processing Structure in Music

2003 • 130 citations

Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease

2005 • 127 citations

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

1998 • 123 citations

Nomenclature for Runt-related (RUNX) proteins

2004 • 119 citations

Mammalian Groucho homologs: Redundancy or specificity?

2005 • 112 citations

Runx3 Regulates Integrin αE/CD103 and CD4 Expression during Development of CD4−/CD8+ T Cells

2005 • 112 citations

CD4/CD8-lineage differentiation in the thymus: from nuclear effectors to membrane signals

2004 • 109 citations

Overexpression of the Runx3 Transcription Factor Increases the Proportion of Mature Thymocytes of the CD8 Single-Positive Lineage

2005 • 81 citations

Localization of the Domains in Runx Transcription Factors Required for the Repression of CD4 in Thymocytes

2004 • 80 citations

Studies on transcriptional regulation of the mucosal T‐cell integrin αEβ7 (CD103)

2001 • 74 citations

Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment

2001 • 67 citations

Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus.

2004 • 63 citations

Epigenetic gene silencing by Runx proteins

2004 • 63 citations

VWRPY motif–dependent and –independent roles of AML1/Runx1 transcription factor in murine hematopoietic development

2003 • 59 citations

E-cadherin-mediated interactions of thymic epithelial cells with CD103+ thymocytes lead to enhanced thymocyte cell proliferation

2002 • 54 citations

Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4−/CD8+ Thymocytes

2003 • 50 citations

Functional Domains of Runx1 Are Differentially Required for CD4 Repression, TCRβ Expression, and CD4/8 Double-Negative to CD4/8 Double-Positive Transition in Thymocyte Development

2005 • 35 citations