The RUNX3 gene – sequence, structure and regulated expression

Current protocols in molecular biology

1988 • 7,584 citations

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

1997 • 4,168 citations

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

1997 • 2,784 citations

Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL

1998 • 1,474 citations

Oncogenic Transcription Factors in the Human Acute Leukemias

1997 • 1,227 citations

A Role for Hematopoietic Stem Cells in Promoting Angiogenesis

2000 • 512 citations

AML1, AML2, and AML3, the Human Members of the runt domain Gene-Family: cDNA Structure, Expression, and Chromosomal Localization

1994 • 403 citations

Cleidocranial dysplasia: clinical and molecular genetics.

1999 • 400 citations

Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene

2000 • 246 citations

An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms.

1995 • 232 citations

THE AML1‐ETO CHIMAERIC TRANSCRIPTION FACTOR IN ACUTE MYELOID LEUKAEMIA: BIOLOGY AND CLINICAL SIGNIFICANCE

1999 • 214 citations

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis

2001 • 181 citations

Molecular basis of tissue‐specific gene expression mediated by the Runt domain transcription factor PEBP2/CBF

1999 • 180 citations

Cloning, mapping and expression of PEBP2αC, a third gene encoding the mammalian Runt domain

1995 • 160 citations

Expression of the human acute myeloid leukemia gene AML1 is regulated by two promoter regions.

1996 • 153 citations

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

2001 • 149 citations

Genomic structure and isoform expression of the mouse, rat and human Cbfa1/Osf2 transcription factor

1998 • 142 citations

Core-binding factor: a central player in hematopoiesis and leukemia.

1999 • 118 citations

AML-2 is a potential target for transcriptional regulation by the t(8;21) and t(12;21) fusion proteins in acute leukemia.

1996 • 118 citations

Structural basis for the heterodimeric interaction between the acute leukaemia-associated transcription factors AML1 and CBFbeta

2000 • 107 citations

CBF alpha3 (AML2) is induced by TGF-beta1 to bind and activate the mouse germline Ig alpha promoter.

1998 • 105 citations

CBFα3 (AML2) Is Induced by TGF-β1 to Bind and Activate the Mouse Germline Ig α Promoter

1998 • 97 citations

A Large Variety of Alternatively Spliced and Differentially Expressed mRNAs Are Encoded by the Human Acute Myeloid Leukemia Gene AML1

1996 • 96 citations

Genomic organization, expression of the human CBFA1 gene, and evidence for an alternative splicing event affecting protein function

1998 • 89 citations

The Human ICAM-2 Promoter is Endothelial Cell-specific in Vitro and in Vivo and Contains Critical Sp1 and GATA Binding Sites

1998 • 79 citations

A Novel Transcript Encoding an N-Terminally Truncated AML1/PEBP2αB Protein Interferes with Transactivation and Blocks Granulocytic Differentiation of 32Dcl3 Myeloid Cells

1997 • 79 citations

An efficient directional cloning system to construct cDNA libraries containing full-length inserts at high frequency

1989 • 66 citations

Regulation of AML2/CBFA3 in Hematopoietic Cells through the Retinoic Acid Receptor α-Dependent Signaling Pathway

1999 • 57 citations

Transcriptional regulation of T-cell genes during T-cell development

1994 • 48 citations

Isolation and characterization of the distal promoter region of mouse Cbfa1

1999 • 42 citations

GESTALT: a workbench for automatic integration and visualization of large-scale genomic sequence analyses

2000 • 34 citations

Transcriptional regulation of early B-lymphocyte differentiation.

2000 • 30 citations

Expression of AML1-d, a short human AML1 isoform, in embryonic stem cells suppresses in vivo tumor growth and differentiation

1998 • 29 citations

Transcriptional regulation of early B‐lymphocyte differentiation

2000 • 27 citations

Mapping of the mouse homolog of the human runt domain gene, AML2, to the distal region of mouse chromosome 4

1995 • 23 citations

AML1 haploinsufficiency, gene dosage, and the predisposition to acute leukemia

2000 • 21 citations

Identification and chromosomal mapping of a third mouse runt-like locus

1995 • 18 citations

Functional Properties of the Neuronal Nicotinic Acetylcholine Receptor β3 Promoter in the Developing Central Nervous System

1998 • 14 citations

Deleted Work

1955 • 0 citations