Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease

Dendritic cells and the control of immunity

1998 • 14,345 citations

Tolerogenic Dendritic Cells

2003 • 3,131 citations

Chemokines and leukocyte traffic

1998 • 2,755 citations

Points of control in inflammation

2002 • 2,599 citations

CCR7 Coordinates the Primary Immune Response by Establishing Functional Microenvironments in Secondary Lymphoid Organs

1999 • 2,326 citations

Robbins pathologic basis of disease

1989 • 1,872 citations

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

2002 • 1,343 citations

IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS

1999 • 1,047 citations

Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 • 1,030 citations

Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

2002 • 1,019 citations

CCR7 Governs Skin Dendritic Cell Migration under Inflammatory and Steady-State Conditions

2004 • 997 citations

Differential Requirements for Runx Proteins in CD4 Repression and Epigenetic Silencing during T Lymphocyte Development

2002 • 712 citations

Development of Spontaneous Airway Changes Consistent with Human Asthma in Mice Lacking T-bet

2002 • 633 citations

Asthma: an epidemic of dysregulated immunity

2002 • 613 citations

In vivo depletion of lung CD11c+ dendritic cells during allergen challenge abrogates the characteristic features of asthma

2005 • 610 citations

Immature dendritic cells generated with low doses of GM-CSF in the absence of IL-4 are maturation resistant and prolong allograft survivalin vivo

2000 • 477 citations

The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons

2002 • 424 citations

Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral Tolerance

2003 • 420 citations

AML1, AML2, and AML3, the Human Members of the runt domain Gene-Family: cDNA Structure, Expression, and Chromosomal Localization

1994 • 403 citations

The immunogenetics of asthma and eczema: a new focus on the epithelium

2004 • 384 citations

Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

2003 • 380 citations

EBI1/CCR7 Is a New Member of Dendritic Cell Chemokine Receptor That Is Up-Regulated upon Maturation

1998 • 377 citations

Accelerated Migration of Respiratory Dendritic Cells to the Regional Lymph Nodes Is Limited to the Early Phase of Pulmonary Infection

2003 • 362 citations

Taking our breath away: dendritic cells in the pathogenesis of asthma

2003 • 340 citations

To respond or not to respond: T cells in allergic asthma

2003 • 334 citations

RUNX transcription factors as key targets of TGF-β superfamily signaling

2003 • 322 citations

Runx3 controls the axonal projection of proprioceptive dorsal root ganglion neurons

2002 • 301 citations

Autoimmunity through Cytokine-Induced Dendritic Cell Activation

2004 • 294 citations

Runx3 regulates mouse TGF-β-mediated dendritic cell function and its absence results in airway inflammation

2004 • 281 citations

Structure and regulated expression of mammalian RUNX genes

2004 • 276 citations

TGF-beta promotes immune deviation by altering accessory signals of antigen-presenting cells.

1998 • 217 citations

A Restricted Subset of Dendritic Cells Captures Airborne Antigens and Remains Able to Activate Specific T Cells Long after Antigen Exposure

2002 • 204 citations

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis

2001 • 181 citations

Activation of Peroxisome Proliferator-Activated Receptor-γ in Dendritic Cells Inhibits the Development of Eosinophilic Airway Inflammation in a Mouse Model of Asthma

2004 • 167 citations

Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia

2004 • 166 citations

Human alveolar macrophages present antigen ineffectively due to defective expression of B7 costimulatory cell surface molecules.

1995 • 162 citations

TGF-β Promotes Immune Deviation by Altering Accessory Signals of Antigen-Presenting Cells

1998 • 155 citations

Time to draw breath: asthma-susceptibility genes are identified

2004 • 154 citations

Fc epsilon receptor I on dendritic cells delivers IgE-bound multivalent antigens into a cathepsin S-dependent pathway of MHC class II presentation.

1998 • 149 citations

CC chemokine receptor-7 on dendritic cells is induced after interaction with apoptotic tumor cells: critical role in migration from the tumor site to draining lymph nodes.

2000 • 148 citations

Asthma and atopy – a total genome scan for susceptibility genes

2002 • 137 citations

MOUSE MODELS OF AIRWAY RESPONSIVENESS: Physiological Basis of Observed Outcomes and Analysis of Selected Examples Using These Outcome Indicators

1999 • 134 citations

Toward the Neural Basis of Processing Structure in Music

2003 • 130 citations

Fcε Receptor I on Dendritic Cells Delivers IgE-Bound Multivalent Antigens into a Cathepsin S-Dependent Pathway of MHC Class II Presentation

1998 • 121 citations

Human dendritic cell 1 and dendritic cell 2 subsets express FcεRI

2003 • 121 citations

Monocyte-Derived Dendritic Cells Induce a House Dust Mite-Specific Th2 Allergic Inflammation in the Lung of Humanized SCID Mice: Involvement of CCR7

2002 • 111 citations

Chemotactic Response Toward Chemokines and Its Regulation by Transforming Growth Factor-β1 of Murine Bone Marrow Hematopoietic Progenitor Cell-Derived Different Subset of Dendritic Cells

1999 • 79 citations

Mechanism of inhibition of LPS-induced IL-12p40 production by IL-10 and TGF-β in ANA-1 cells

1998 • 78 citations

Something old, something new: Indoor endotoxin, allergens and asthma

2004 • 74 citations

Functional IL-10 Deficiency in the Lung of Cystic Fibrosis (cftr−/−) and IL-10 Knockout Mice Causes Increased Expression and Function of B7 Costimulatory Molecules on Alveolar Macrophages

2002 • 73 citations

Murine models of asthma in understanding immune dysregulation in human asthma

2000 • 68 citations

Role of RUNX in autoimmune diseases linking rheumatoid arthritis, psoriasis and lupus.

2004 • 63 citations

Runx3 knockouts and stomach cancer

2003 • 57 citations

A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families

2002 • 53 citations

Morpholino Antisense Oligonucleotide-Mediated Gene Knockdown During Thymocyte Development Reveals Role for Runx3 Transcription Factor in CD4 Silencing During Development of CD4−/CD8+ Thymocytes

2003 • 50 citations

Why are dendritic cells important in allergic diseases of the respiratory tract?

2003 • 34 citations

The importance of maximal airway response to methacholine in the prediction of wheezing development in patients with cough‐variant asthma

2002 • 27 citations

[Interdisciplinary physio-reflexotherapy in the treatment of headache].

1999 • 14 citations