B-50, the growth associated protein-43: modulation of cell morphology and communication in the nervous system

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1995 • 4,387 citations

The molecular heterogeneity of protein kinase C and its implications for cellular regulation

1988 • 4,243 citations

SNAP receptors implicated in vesicle targeting and fusion

1993 • 3,220 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Cell Death During Development of the Nervous System

1991 • 3,033 citations

Vergleichende Lokalisationslehre der Großhirnrinde : in ihren Prinzipien dargestellt auf Grund des Zellenbaues

1909 • 2,582 citations

The synaptic vesicle cycle: a cascade of protein–protein interactions

1995 • 2,004 citations

The establishment of polarity by hippocampal neurons in culture

1988 • 1,820 citations

The Fine Structure of the Nervous System: Neurons and Their Supporting Cells

1991 • 1,522 citations

Subregion- and Cell Type–Restricted Gene Knockout in Mouse Brain

1996 • 1,272 citations

Mechanisms of Memory

1986 • 1,252 citations

Developmental Neurobiology

1978 • 1,211 citations

Axonal Growth-Associated Proteins

1989 • 1,118 citations

Cell Adhesion Molecules

1983 • 1,017 citations

Molecular dissection of the secretory pathway

1992 • 985 citations

In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases

1995 • 849 citations

Tubular membrane invaginations coated by dynamin rings are induced by GTP-γS in nerve terminals

1995 • 760 citations

MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium–calmodulin

1992 • 728 citations

Polarity orientation of microtubules in hippocampal neurons: uniformity in the axon and nonuniformity in the dendrite.

1988 • 716 citations

Nerve growth factor: from neurotrophin to neurokine

1996 • 687 citations

Neuronal Polarity

1994 • 658 citations

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

1985 • 636 citations

Principles of neural development

1985 • 627 citations

Induction of nerve growth factor receptor in Schwann cells after axotomy.

1986 • 614 citations

Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice

1995 • 612 citations

Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems

1981 • 583 citations

Inhibitors of Neurite Growth

1993 • 545 citations

A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism, and synaptic plasticity

1987 • 543 citations

Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones.

1986 • 526 citations

Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

1996 • 522 citations

ATP-dependent inositide phosphorylation required for Ca2+-activated secretion

1995 • 508 citations

Modified hippocampal long-term potentiation in PKCγ-mutant mice

1993 • 507 citations

A Protein Induced During Nerve Growth (GAP-43) is a Major Component of Growth-Cone Membranes

1986 • 505 citations

Changes in axonally transported proteins during axon regeneration in toad retinal ganglion cells.

1981 • 495 citations

Vision and Visual Dysfunction

1991 • 485 citations

Response of facial and rubrospinal neurons to axotomy: changes in mRNA expression for cytoskeletal proteins and GAP-43

1991 • 478 citations

Peripheral injury enhances central regeneration of primary sensory neurones

1984 • 468 citations

Vision and Visual Dysfunction

1992 • 463 citations

The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture

1991 • 463 citations

Neuronal loss induced in limbic pathways by kindling: evidence for induction of hippocampal sclerosis by repeated brief seizures

1994 • 461 citations

The functional organization of the hippocampal dentate gyrus and its relevance to the pathogenesis of temporal lobe epilepsy

1994 • 460 citations

Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo

1993 • 440 citations

A protein associated with axon growth, GAP-43, is widely distributed and developmentally regulated in rat CNS

1986 • 435 citations

G0 is a major growth cone protein subject to regulation by GAP-43

1990 • 422 citations

Development of neuronal polarity: GAP-43 distinguishes axonal from dendritic growth cones

1988 • 413 citations

Synapsin I bundles F-actin in a phosphorylation-dependent manner

1987 • 409 citations

Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brain

1988 • 390 citations

Long-term potentiation of the perforant path in vivo is associated with increased glutamate release

1982 • 387 citations

Neuronal pathfinding is abnormal in mice lacking the neuronal growth cone protein GAP-43

1995 • 384 citations

Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43.

1989 • 383 citations

Membrane fusion machinery: Insights from synaptic proteins

1993 • 380 citations

Selective reinnervation of hippocampal area CA1 and the fascia dentata after destruction of CA3-CA4 afferents with kainic acid

1980 • 380 citations

Unconventional myosins

1992 • 374 citations

Synaptic Vesicles and Exocytosis

1994 • 371 citations

Amyotrophic lateral sclerosis: Part 1. Clinical features, pathology, and ethical issues in management

1985 • 369 citations

Primary structure and transcriptional regulation of GAP-43, a protein associated with nerve growth

1987 • 358 citations

Cloning of Complementary DNA for GAP-43, a Neuronal Growth-Related Protein

1987 • 351 citations

Primary structure and cellular localization of chicken brain myosin-V (p190), an unconventional myosin with calmodulin light chains.

1992 • 345 citations

Regulation of calmodulin binding to P-57. A neurospecific calmodulin binding protein.

1987 • 334 citations

Brief seizure episodes induce long-term potentiation and mossy fibre sprouting in the hippocampus

1990 • 332 citations

Neuronal man : the biology of mind

1985 • 325 citations

The dynamic role of palmitoylation in signal transduction

1995 • 315 citations

Expression of the growth-associated protein GAP-43 in adult rat retinal ganglion cells following axon injury

1991 • 314 citations

The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats

1989 • 300 citations

Structure of the regulatory domain of scallop myosin at 2.8 Ä resolution

1994 • 296 citations

Correlation between long‐term potentiation and release of endogenous amino acids from dentate gyrus of anaesthetized rats.

1986 • 289 citations

Adp-Ribosylating Toxins and G Proteins: Insights into Signal Transduction

1990 • 285 citations

Labeling Neural Cells Using Adenoviral Gene Transfer of Membrane-Targeted GFP

1996 • 280 citations

Peripheral Nerve Regeneration

1990 • 279 citations

Purification and characterization of a brain-specific protein kinase C substrate, neurogranin (p17). Identification of a consensus amino acid sequence between neurogranin and neuromodulin (GAP43) that corresponds to the protein kinase C phosphorylation site and the calmodulin-binding domain.

1991 • 274 citations

Imaging of Memory-Specific Changes in the Distribution of Protein Kinase C in the Hippocampus

1989 • 271 citations

Inhibition of noradrenaline release by antibodies to B-50 (GAP-43)

1989 • 267 citations

Identification and characterization of the calmodulin-binding domain of neuromodulin, a neurospecific calmodulin-binding protein.

1988 • 262 citations

Biochemistry of Altered Brain Proteins in Alzheimer's Disease

1989 • 261 citations

Signal transduction and membrane traffic: The PITP/phosphoinositide connection

1995 • 261 citations

How chicks make memories: the cellular cascade from c-fos to dendritic remodelling

1991 • 257 citations

Expression of growth-associated protein B-50 (GAP43) in dorsal root ganglia and sciatic nerve during regenerative sprouting

1989 • 249 citations

Regulatory functions of calmodulin

1991 • 248 citations

Getting the message from the gene to the synapse: sorting and intracellular transport of RNA in neurons

1992 • 235 citations

Myelin-associated inhibitors of neurite growth and regeneration in the CNS

1990 • 227 citations

Regulation of free calmodulin levels by neuromodulin: neuron growth and regeneration

1990 • 226 citations

Purification of a novel calmodulin-binding protein from bovine cerebral cortex membranes

1983 • 225 citations

Phosphorylation of B‐50 Protein by Calcium‐Activated, Phospholipid‐Dependent Protein Kinase and B‐50 Protein Kinase

1983 • 224 citations

Increased transport of 44,000- to 49,000-dalton acidic proteins during regeneration of the goldfish optic nerve: a two-dimensional gel analysis

1983 • 220 citations

Recollections of My Life

1989 • 218 citations

Expression of GAP-43, a rapidly transported growth-associated protein, and class II beta tubulin, a slowly transported cytoskeletal protein, are coordinated in regenerating neurons

1989 • 217 citations

Membrane trafficking in the presynaptic nerve terminal

1995 • 217 citations

The Neuronal Growth-Associated Protein GAP-43 Induces Filopodia in Non-Neuronal Cells

1989 • 216 citations

Changes in the distribution of GAP-43 during the development of neuronal polarity

1990 • 216 citations

Calcineurin Inhibition of Dynamin I GTPase Activity Coupled to Nerve Terminal Depolarization

1994 • 215 citations

Growth-associated protein GAP-43 is expressed selectively in associative regions of the adult human brain.

1988 • 212 citations

Fate of GAP-43 in ascending spinal axons of DRG neurons after peripheral nerve injury: delayed accumulation and correlation with regenerative potential

1991 • 211 citations

GAP-43 is expressed by nonmyelin-forming Schwann cells of the peripheral nervous system.

1992 • 210 citations

Common and distinct fusion proteins in axonal growth and transmitter release

1996 • 209 citations

Reactive synaptogenesis assessed by synaptophysin immunoreactivity is associated with GAP-43 in the dentate gyrus of the adult rat

1991 • 207 citations

Signal transduction and the actin cytoskeleton: the roles of MARCKS and profilin

1992 • 203 citations

Purification and Some Characteristics of an ACTH‐Sensitive Protein Kinase and Its Substrate Protein in Rat Brain Membranes

1980 • 202 citations

Differential subcellular localization of particular mRNAs in hippocampal neurons in culture

1990 • 201 citations

Direct relation of long-term synaptic potentiation to phosphorylation of membrane protein F1, a substrate for membrane protein kinase C

1986 • 201 citations

Rab proteins in regulated exocytosis

1994 • 197 citations

The kindling model of epilepsy

1983 • 197 citations

Inverse patterns of myelination and GAP‐43 expression in the adult CNS: Neurite growth inhibitors as regulators of neuronal plasticity?

1994 • 197 citations

Neuroplasticity in the olfactory system: Differential effects of central and peripheral lesions of the primary olfactory pathway on the expression of B‐50/GAP43 and the olfactory marker protein

1990 • 197 citations

Subtractive cDNA cloning of RC3, a rodent cortex‐enriched mRNA encoding a novel 78 residue protein

1990 • 193 citations

Epilepsy

1993 • 190 citations

Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.

1992 • 188 citations

Protein kinase C phosphorylates a 47 Mr protein (F1) directly related to synaptic plasticity

1985 • 186 citations

Ca2+ and secretory-vesicle dynamics

1995 • 185 citations

Nerve growth cones isolated from fetal rat brain. III. Calcium- dependent protein phosphorylation

1985 • 185 citations

Regulation of microtubule dynamics by the neuronal growth-associated protein SCG10

1997 • 184 citations

Absence of persistent spreading, branching, and adhesion in GAP-43-depleted growth cones.

1995 • 183 citations

Are Disturbances of Sorbitol, Phosphoinositide, and Na+-K+-ATPase Regulation Involved in Pathogenesis of Diabetic Neuropathy?

1988 • 183 citations

Comparison of the immunocytochemical distribution of the phosphoprotein B-50 in the cerebellum and hippocampus of immature and adult rat brain

1986 • 182 citations

Elevated synthesis of an axonally transported protein correlates with axon outgrowth in normal and injured pyramidal tracts

1986 • 182 citations

GAP‐43 as a plasticity protein in neuronal form and repair

1992 • 182 citations

Protein Kinase C Substrates from Bovine Brain

1989 • 182 citations

Dual regulation of GAP-43 gene expression by nerve growth factor and glucocorticoids.

1988 • 181 citations

ACTH, cyclic nucleotides, and brain protein phosphorylation in vitro

1976 • 181 citations

Phosphorylation of B‐50 (GAP43) Is Correlated with Neurotransmitter Release in Rat Hippocampal Slices

1989 • 181 citations

GAP-43 in growth cones is associated with areas of membrane that are tightly bound to substrate and is a component of a membrane skeleton subcellular fraction

1990 • 178 citations

Modulation of brain polyphosphoinositide metabolism by ACTH-sensitive protein phosphorylation

1980 • 178 citations

Primary sensory neurons exhibit altered gene expression in a rat model of neuropathic pain

1994 • 176 citations

A membrane-targeting signal in the amino terminus of the neuronal protein GAP-43

1989 • 176 citations

Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo.

1991 • 174 citations

Affinity‐Purified Anti‐B‐50 Protein Antibody: Interference with the Function of the Phosphoprotein B‐50 in Synaptic Plasma Membranes

1983 • 173 citations

Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones.

1993 • 173 citations

Primary structure and mRNA localization of protein F1, a growth-related protein kinase C substrate associated with synaptic plasticity.

1987 • 172 citations

Mapping the development of the rat brain by GAP-43 immunocytochemistry

1991 • 171 citations

Preferential addition of newly synthesized membrane protein at axonal growth cones

1995 • 171 citations

Gap‐43 immunoreactivity and axon regeneration in retinal ganglion cells of the rat

1994 • 171 citations

Axonal transport and localization of B-50/GAP-43-like immunoreactivity in regenerating sciatic and facial nerves of the rat

1989 • 168 citations

Classical conditioning induces long-term translocation of protein kinase C in rabbit hippocampal CA1 cells.

1988 • 167 citations

Characterization of the calmodulin binding domain of neuromodulin. Functional significance of serine 41 and phenylalanine 42.

1991 • 165 citations

Effect of peripheral axotomy on the fine structure and histochemistry of the Rolando substance: Degenerative atrophy of central processes of pseudounipolar cells

1976 • 163 citations

Changes in cytoskeletal protein synthesis following axon injury and during axon regeneration

1992 • 163 citations

Distribution and phosphorylation of the growth-associated protein GAP- 43 in regenerating sympathetic neurons in culture

1988 • 162 citations

Transgenic Animal Technology: A Laboratory Handbook

2014 • 161 citations

Phosphorylation of the presynaptic protein B-50 (GAP-43) is increased during electrically induced long-term potentiation

1992 • 160 citations

Cytoskeleton dynamics during neurotransmitter release

1993 • 159 citations

Transmitter Glutamate Release from Isolated Nerve Terminals: Evidence for Biphasic Release and Triggering by Localized Ca²⁺

1991 • 158 citations

Asymmetric retraction of growth cone filopodia following focal inactivation of calcineurin

1995 • 158 citations

Dephosphorylation of Neuromodulin by Calcineurin

1989 • 157 citations

Role of the growth-associated protein B-50/GAP-43 in neuronal plasticity

1991 • 156 citations

B‐50 (GAP‐43): Biochemistry and Functional Neurochemistry of a Neuron‐Specific Phosphoprotein

1991 • 155 citations

Up-regulation of GAP-43 and growth of axons in rat spinal cord after compression injury

1993 • 152 citations

Localization of the growth-associated phosphoprotein GAP-43 (B-50, F1) in the human cerebral cortex

1989 • 151 citations

The neuronal growth-associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs

1987 • 151 citations

Posttranscriptional regulation of GAP-43 gene expression in PC12 cells through protein kinase C-dependent stabilization of the mRNA.

1993 • 149 citations

Light-microscopic immunolocalization of the growth- and plasticity-associated protein GAP-43 in the developing rat brain

1988 • 147 citations

On the number and nature of regenerating myelinated axons after lesions of cutaneous nerves in the cat.

1981 • 144 citations

Transfection of PC12 cells with the human GAP-43 gene: effects on neurite outgrowth and regeneration

1990 • 143 citations

The Nerve Growth Cone

1991 • 142 citations

Phosphoprotein B-50 in nerve growth cones from fetal rat brain

1985 • 142 citations

Evidence That the Synaptic Phosphoprotein B‐50 Is Localized Exclusively in Nerve Tissue

1982 • 142 citations

The Role of Synaptic Proteins in the Pathogenesis of Disorders of the Central Nervous System

1993 • 140 citations

Correlation between GAP43 and nerve growth factor receptors in rat sensory neurons

1990 • 140 citations

Deciphering Alzheimer's Disease: The Amyloid Precursor Protein Yields New Clues

1990 • 140 citations

mRNA at the synapse: analysis of a synaptosomal preparation enriched in hippocampal dendritic spines

1993 • 139 citations

Lectin labeling of sprouting neurons. II. Relative movement and appearance of glycoconjugates during plasmalemmal expansion.

1981 • 139 citations

Cloning of human GAP 43: Growth association and ischemic resurgence

1988 • 138 citations

Hippocampal neurobiological mechanisms of age-related memory dysfunction

1988 • 138 citations

The pattern of GAP-43 immunostaining changes in the rat hippocampal formation during reactive synaptogenesis

1990 • 137 citations

SYSTEMS OF MATERIAL TRANSPORT IN NERVE FIBERS (AXOPLASMIC TRANSPORT) RELATED TO NERVE FUNCTION AND TROPHIC CONTROL*

1974 • 135 citations

Phospholipid-mediated delivery of anti-GAP-43 antibodies into neuroblastoma cells prevents neuritogenesis

1991 • 131 citations

Perspectives on axonal regeneration in the mammalian CNS

1994 • 126 citations

Injury‐associated induction of GAP‐43 expression displays axon branch specificity in rat dorsal root ganglion neurons

1993 • 125 citations

Freeze-substitution and Lowicryl HM20 embedding of fixed rat brain: suitability for immunogold ultrastructural localization of neural antigens.

1991 • 124 citations

Characterization of murine cDNAs encoding P-57, a neural-specific calmodulin-binding protein.

1987 • 124 citations

The sensory-motor role of growth cone filopodia

1995 • 124 citations

Long-term potentiation as synaptic dialogue

1993 • 122 citations

Distribution of GAP‐43 mRNA in the adult rat brain

1993 • 120 citations

Differential regulation of peripherin and neurofilament gene expression in regenerating rat DRG neurons

1990 • 119 citations

Schwann cells: early lineage, regulation of proliferation and control of myelin formation

1992 • 119 citations

B-50 phosphorylation and polyphosphoinositide metabolism in nerve growth cone membranes

1988 • 119 citations

Time-lapse video analysis of retinal ganglion cell axon pathfinding at the mammalian optic chiasm: Growth cone guidance using intrinsic chiasm cues

1993 • 118 citations

Nerve growth factor-induced changes in the intracellular localization of the protein kinase C substrate B-50 in pheochromocytoma PC12 cells.

1989 • 117 citations

Neurite outgrowth in PC12 cells deficient in GAP-43

1991 • 116 citations

Rapid changes in the distribution of GAP-43 correlate with the expression of neuronal polarity during normal development and under experimental conditions.

1990 • 115 citations

B‐50/GAP43 Expression Correlates with Process Outgrowth in the Embryonic Mouse Nervous System

1990 • 112 citations

Denervation of the motor endplate results in the rapid expression by terminal Schwann cells of the growth-associated protein GAP-43

1992 • 112 citations

Palmitoylation alters protein activity: blockade of G(o) stimulation by GAP-43.

1992 • 112 citations

Human GAP 43: Its deduced amino acid sequence and chromosomal localization in mouse and human

1988 • 109 citations

Evidence for a Single Protein Kinase C‐Mediated Phosphorylation Site in Rat Brain Protein B‐50

1989 • 109 citations

Growth-associated proteins and the curious dichotomies of nerve regeneration

1984 • 109 citations

The downregulation of growth-associated proteins in motoneurons at the onset of synapse elimination is controlled by muscle activity and IGF1

1992 • 108 citations

Developmental and plasticity-related differential expression of two SNAP-25 isoforms in the rat brain

1996 • 107 citations

Altered Neurotrophin mRNA Levels in Peripheral Nerve and Skeletal Muscle of Experimentally Diabetic Rats

1995 • 106 citations

Temporal Differences in the Phosphorylation State of Pre- and Postsynaptic Protein Kinase C Substrates B-50/GAP-43 and Neurogranin during Long Term Potentiation

1995 • 106 citations

Dorsal root ganglion cell death and surviving cell numbers in relation to the development of sensory innervation in the rat hindlimb

1994 • 105 citations

Selective expression of protein F1/(GAP-43) mRNA in pyramidal but not granule cells of the hippocampus

1991 • 104 citations

GAP-43 expression in developing cutaneous and muscle nerves in the rat hindlimb

1991 • 104 citations

The effects of a lesion or a peripheral nerve graft on GAP-43 upregulation in the adult rat brain: an in situ hybridization and immunocytochemical study

1995 • 104 citations

Modulation of the activity of purified phosphatidylinositol 4-phosphate kinase by phosphorylated and dephosphorylated B-50 protein

1985 • 103 citations

A neural-specific GAP-43 core promoter located between unusual DNA elements that interact to regulate its activity

1992 • 102 citations

Dependence of GAP43 (B50, F1) transport on axonal regeneration in rat dorsal root ganglion neurons

1988 • 102 citations

Resolution of Rat Brain Synaptic Phosphoprotein B‐50 into Multiple Forms by Two‐Dimensional Electrophoresis: Evidence for Multisite Phosphorylation

1985 • 101 citations

Rab5, an early acting endosomal GTPase, supports in vitro endosome fusion without GTP hydrolysis.

1994 • 101 citations

Phosphorylation-site mutagenesis of the growth-associated protein GAP-43 modulates its effects on cell spreading and morphology.

1993 • 101 citations

GAP‐43 mRNA in Rat Spinal Cord and Dorsal Root Ganglia Neurons: Developmental Changes and Re‐expression Following Peripheral Nerve Injury

1992 • 100 citations

Expression of GAP-43 mRNA in the adult mammalian spinal cord under normal conditions and after different types of lesions, with special reference to motoneurons

1992 • 100 citations

GAP-43 expression in the developing rat lumbar spinal cord

1991 • 99 citations

Development of subcellular mRNA compartmentation in hippocampal neurons in culture

1994 • 98 citations

Glucocorticoids and the expression of mRNAs for neurotrophins, their receptors and GAP-43 in the rat hippocampus

1994 • 97 citations

Neuromodulin (GAP43): a neuronal protein kinase C substrate is also present in 0-2A glial cell lineage. Characterization of neuromodulin in secondary cultures of oligodendrocytes and comparison with the neuronal antigen.

1990 • 97 citations

Selective conservation of GAP-43 structure in vertebrate evolution

1989 • 97 citations

Axonal transport and the cytoskeleton

1993 • 97 citations

Distribution of GAP-43 mRNA in the brain stem of adult rats as evidenced by in situ hybridization: localization within monoaminergic neurons

1991 • 96 citations

GAP-43 amino terminal peptides modulate growth cone morphology and neurite outgrowth

1994 • 96 citations

Intrinsic versus extrinsic factors in determining the regeneration of the central processes of rat dorsal root ganglion neurons: The influence of a peripheral nerve graft

1996 • 96 citations

B-50/GAP43 is localized at the cytoplasmic side of the plasma membrane in developing and adult rat pyramidal tract

1989 • 96 citations

Purification and molecular cloning of a novel acidic calmodulin binding protein from rat brain

1993 • 96 citations

An intracellular guanine nucleotide release protein for G0. GAP-43 stimulates isolated alpha subunits by a novel mechanism.

1991 • 96 citations

Epilepsy: models, mechanisms and concepts

1994 • 95 citations

Axon guidance: A compelling case for repelling growth cones

1995 • 95 citations

Ultrastructural immunocytochemical localization of B-50/GAP43, a protein kinase C substrate, in isolated presynaptic nerve terminals and neuronal growth cones

1989 • 93 citations

The neuronal growth-associated protein GAP-43 (B-50, F1): neuronal specificity, developmental regulation and regional distribution of the human and rat mRNAs

1987 • 92 citations

An electron microscopic analysis of hippocampal neurons developing in culture: early stages in the emergence of polarity

1993 • 91 citations

Observations on the hypothalamo-posthypophyseal system of the posterior lobectomized rat

1962 • 91 citations

The mechanism and regulation of fast axonal transport

1989 • 90 citations

NMDA receptor blockade prevents kainate induction of protein F1/GAP-43 mRNA in hippocampal granule cells and subsequent mossy fiber sprouting in the rat

1995 • 89 citations

Localization of amyloid precursor protein in GAP43-immunoreactive aberrant sprouting neurites in Alzheimer's disease

1992 • 88 citations

The Earliest Patterns of Neuronal Differentiation and Migration in the Mammalian Central Nervous System

1995 • 87 citations

Remodeling of B-50 (GAP-43)- and NSE-immunoreactive mucosal nerves in the intestines of rats infected with Nippostrongylus brasiliensis

1991 • 87 citations

The kinase c substrate protein b-50 and axonal regeneration

1986 • 87 citations

Experimental diabetic neuropathy: similar changes of slow axonal transport and axonal size in different animal models

1988 • 87 citations

Intracellular sorting of neuromodulin (GAP-43) mutants modified in the membrane targeting domain

1994 • 85 citations

Protein synthesis and axonal transport in goldfish retinal ganglion cells during regeneration accelerated by a conditioning lesion

1982 • 85 citations

Activation of protein kinase C by arachidonic acid selectively enhances the phosphorylation of GAP-43 in nerve terminal membranes

1993 • 85 citations

Ultrastructural and Biochemical Characterization of Autonomic Neuropathy in Rats with Chronic Streptozotocin Diabetes

1986 • 85 citations

Early terminal and nodal sprouting of motor axons after botulinum toxin

1989 • 83 citations

Axonal transport of calmodulin: a physiologic approach to identification of long-term associations between proteins.

1981 • 82 citations

Synaptic connections made by axons regenerating in the central nervous system of adult mammals

1990 • 82 citations

The interactions of the brain-specific calmodulin-binding protein kinase C substrate, neuromodulin (GAP 43), with membrane phospholipids.

1991 • 81 citations

Time-dependent differences in the increase in GAP-43 expression in dorsal root ganglion cells after peripheral axotomy

1991 • 80 citations

Molecular Properties of the Growth‐Associated Protein GAP‐43 (B‐50)

1987 • 80 citations

Are disturbances of sorbitol, phosphoinositide, and Na+-K+-ATPase regulation involved in pathogenesis of diabetic neuropathy?

1988 • 80 citations

Forward Plasma Membrane Flow in Growing Nerve Processes

1993 • 80 citations

Induction of F1/GAP-43 gene: expression in hippocampal granule cells after seizures

1993 • 79 citations

Targeted disruption of Ca2+-calmodulin signaling in Drosophila growth cones leads to stalls in axon extension and errors in axon guidance

1995 • 79 citations

Chicken Growth‐Associated Protein GAP‐43 Is Tightly Bound to the Actin‐Rich Neuronal Membrane Skeleton

1990 • 79 citations

Delayed kindling development after rapidly recurring seizures: relation to mossy fiber sprouting and neurotrophin, GAP-43 and dynorphin gene expression

1996 • 78 citations

Cellular influences on RNA sorting in neurons and glia: an in situ hybridization histochemical study

1994 • 77 citations

Directed expression of the growth-associated protein B-50/GAP-43 to olfactory neurons in transgenic mice results in changes in axon morphology and extraglomerular fiber growth

1995 • 77 citations

GAP-43 immunoreactivity is widespread in the autonomic neurons and sensory neurons of the rat

1992 • 77 citations

Transient patterns of GAP‐43 expression during the formation of barrels in the rat somatosensory cortex

1990 • 76 citations

Primary structure of the neuron-specific phosphoprotein B-50 is identical to growth-associated protein GAP-43

1987 • 76 citations

Down‐regulation of GAP‐43 During Oligodendrocyte Development and Lack of Expression by Astrocytes In Vivo: Implications for Macroglial Differentiation

1991 • 76 citations

Dephosphorylation of Protein Kinase C Substrates, Neurogranin, Neuromodulin, and MARCKS, by Calcineurin and Protein Phosphatases 1 and 2A

1995 • 76 citations

Protein kinase C activity, translocation, and conventional isoforms in aging rat brain

1995 • 75 citations

Calcium‐Independent γ‐Aminobutyric Acid Release from Growth Cones: Role of γ‐Aminobutyric Acid Transport

1991 • 75 citations

GAP-43 augments G protein-coupled receptor transduction in Xenopus laevis oocytes.

1993 • 74 citations

Intrinsic Neuronal Determinants Locally Regulate Extrasynaptic and Synaptic Growth at the Adult Neuromuscular Junction

1997 • 74 citations

Light- and electron-microscopical study of phosphoprotein B-50 following denervation and reinnervation of the rat soleus muscle

1988 • 73 citations

Noradrenaline Release from Streptolysin O‐Permeated Rat Cortical Synaptosomes: Effects of Calcium, Phorbol Esters, Protein Kinase Inhibitors, and Antibodies to the Neuron‐Specific Protein Kinase C Substrate B‐50 (GAP‐43)

1991 • 73 citations

Identification, localization, and primary structure of CAP-23, a particle-bound cytosolic protein of early development.

1990 • 72 citations

The 43-kDa neuronal growth-associated protein (GAP-43) is present in plasma membranes of rat astrocytes.

1988 • 72 citations

Targeting of neuromodulin (GAP-43) fusion proteins to growth cones in cultured rat embryonic neurons

1991 • 70 citations

Demonstration of presynaptic protein kinase C activation following long-term potentiation in rat hippocampal slices

1993 • 70 citations

Distribution of growth-associated protein, B-50 (GAP-43) in the mammalian enteric nervous system

1990 • 70 citations

Expression of GAP‐43 in the Granule Cells of Rat Hippocampus After Seizure‐induced Sprouting of Mossy Fibres: In Situ Hybridization and Immunocytochemical Studies

1994 • 70 citations

Protein Targeting in the Neuron

1993 • 70 citations

Regulation of immunoreactive GAP-43 expression in rat cortical macroglia is cell type specific.

1990 • 69 citations

Neural selective activation and temporal regulation of a mammalian GAP-43 promoter in zebrafish

1994 • 69 citations

Antisense GAP‐43 Inhibits the Evoked Release of Dopamine from PC12 Cells

1993 • 68 citations

Amino acid sequence of P-57, a neurospecific calmodulin-binding protein

1987 • 68 citations

Increased Expression of the Growth‐associated Protein GAP‐43 in the Myelin‐free Rat Spinal Cord

1994 • 68 citations

Behavioral effects of phosphatidylserine in aged rats

1981 • 68 citations

Patterns of sprouting and implications for recovery of function.

1988 • 67 citations

Rapid induction by kainic acid of both axonal growth and F1/GAP-43 protein in the adult rat hippocampal granule cells

1996 • 67 citations

GAP-43 transgenic mice: dispersed genomic sequences confer a GAP-43- like expression pattern during development and regeneration

1994 • 66 citations

Depolarization‐Induced Phosphorylation of the Protein Kinase C Substrate B‐50 (GAP‐43) in Rat Cortical Synaptosomes

1990 • 65 citations

Neurite outgrowth and GAP‐43 mRNA expression in cultured adult rat dorsal root ganglion neurons: Effects of NGF or prior peripheral axotomy

1994 • 65 citations

Physicochemical and hydrodynamic characterization of P-57, a neurospecific calmodulin binding protein

1986 • 64 citations

Synthesis and transport of GAP-43 in entorhinal cortex neurons and perforant pathway during lesion-induced sprouting and reactive synaptogenesis

1992 • 64 citations

Nerve growth factor stimulation of GAP-43 phosphorylation in intact isolated growth cones

1991 • 64 citations

Post-transcriptional regulation of GAP-43 rnRNA levels during neuronal differentiation and nerve regeneration

1991 • 63 citations

Discussion

1996 • 63 citations

Identification of two promoter regions in the rat B-50/GAP-43 gene

1994 • 62 citations

Increased Expression of GAP‐43, Somatostatin and Neuropeptide Y mRNA in the Hippocampus During Development of Hippocampal Kindling in Rats

1993 • 62 citations

GAP‐43 phosphorylation is dynamically regulated in individual growth cones

1992 • 62 citations

Phosphorylation of neuromodulin (GAP-43) by casein kinase II. Identification of phosphorylation sites and regulation by calmodulin

1991 • 61 citations

The expression of GAP43 mRNA during the late embryonic and early postnatal development of the CNS of the rat: an in situ hybridization study

1992 • 61 citations

Expression of growth‐associated protein‐43 kD in Schwann cells is regulated by axon‐Schwann cell interactions and cAMP

1994 • 61 citations

Distribution of GAP-43 (B50/F1) mRNA in the adult rat brain by in situ hybridization using an alkaline phosphatase labeled probe

1993 • 60 citations

GAP-43, a protein associated with axon growth, is phosphorylated at three sites in cultured neurons and rat brain.

1992 • 60 citations

Axonal growth during regeneration: a quantitative autoradiographic study.

1980 • 59 citations

The GAP-43 Gene Is a Direct Downstream Target of the Basic Helix-Loop-Helix Transcription Factors

1996 • 59 citations

Distribution of the growth associated protein GAP-43 in the central processes of axotomized primary afferents in the adult rat spinal cord; presence of growth cone-like structures

1991 • 59 citations

The expression of B-50/GAP-43 in Schwann cells is upregulated in degenerating peripheral nerve stumps following nerve injury

1993 • 59 citations

The Relationship of GAP‐43 to the Development and Plasticity of Synaptic Connections^a

1991 • 59 citations

Progress in Facilitating the Recovery of Function after Central Nervous System Trauma

1985 • 59 citations

Immunocytochemical detection of the growth‐associated protein B‐50 by newly characterized monoclonal antibodies in human brain and muscle

1992 • 59 citations

SCG10 expresses growth-associated manner in developing rat brain, but shows a different pattern to p19/stathmin or GAP-43

1995 • 58 citations

Of nerve growth cones, leukocytes and memory: second messenger systems and growth-regulated proteins

1986 • 57 citations

Distinctions between hippocampus of mouse and rat: protein F1/GAP-43 gene expression, promoter activity, and spatial memory

1996 • 57 citations

Increase in α‐CGRP and GAP‐43 in aged motoneurons: A study of peptides, growth factors, and ChAT mRNA in the lumbar spinal cord of senescent rats with symptoms of hindlimb incapacities

1995 • 56 citations

The regulation and function of protein phosphatases in the brain

1991 • 56 citations

Injury induced expression of growth-associated protein-43 in adult mouse retinal ganglion cells In vitro

1994 • 55 citations

PEST sequences in calmodulin-binding proteins

1995 • 55 citations

Transport of cytoskeletal elements from parent axons into regenerating daughter axons

1989 • 54 citations

Determination of Changes in the Phosphorylation State of the Neuron‐Specific Protein Kinase C Substrate B‐50 (GAP43) by Quantitative Immunoprecipitation

1989 • 54 citations

The distribution of GAP-43 in normal rat spinal cord

1993 • 54 citations

Expression of NGF receptor and GAP‐43 mRNA in DRG neurons during collateral sprouting and regeneration of dorsal cutaneous nerves

1994 • 54 citations

Alterations in GAP‐43 and Synapsin Immunoreactivity Provide Evidence for Synaptic Reorganization in Adult Cat Dorsal Lateral Geniculate Nucleus following Retinal Lesions

1994 • 53 citations

Structural plasticity of the adult CNS. Negative control by neurite growth inhibitory signals

1996 • 53 citations

Synaptophysin and Gap-43 proteins in efferent fibers of the inner ear during postnatal development

1995 • 53 citations

Nerve growth cones isolated from fetal rat brain. II. Cyclic adenosine 3':5'-monophosphate (cAMP)-binding proteins and cAMP-dependent protein phosphorylation

1985 • 53 citations

GAP-43 in the axons of mammalian CNS neurons regenerating into peripheral nerve grafts

1991 • 52 citations

Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones

1986 • 52 citations

Evidence for the Binding of Calmodulin to Endogenous B‐50 (GAP‐43) in Native Synaptosomal Plasma Membranes

1990 • 52 citations

Vertebrate Unconventional Myosins

1996 • 52 citations

N‐Terminal‐Specific Anti‐B‐50 (GAP‐43) Antibodies Inhibit Ca²⁺‐Induced Noradrenaline Release, B‐50 Phosphorylation and Dephosphorylation, and Calmodulin Binding

1995 • 49 citations

GAP-43 controls the availability of secretory chromaffin granules for regulated exocytosis by stimulating a granule-associated G0.

1994 • 48 citations

Inhibition of nerve growth factor-induced B-50GAP-43 expression by antisense oligomers interferes with neurite outgrowth of PC12 cells

1992 • 48 citations

Regenerating sensory neurones of diabetic rats express reduced levels of mRNA for GAP-43, γ-preprotachykinin and the nerve growth factor receptors, trkA and p75NGFR

1996 • 48 citations

Phosphorylation of Synaptic Proteins in Chick Forebrain: Changes with Development and Passive Avoidance Training

1988 • 48 citations

A Radioimmunoassay for the Phosphoprotein B‐50: Distribution in Rat Brain

1986 • 48 citations

Reactive astrocytes in the kainic acid-damaged hippocampus have the phenotypic features of type-2 astrocytes

1993 • 48 citations

Ontogeny, sex dimorphism, and neonatal sex hormone determination of synapse-associated messenger RNAs in rat brain

1993 • 48 citations

Effect of sciatic nerve section on neural ingrowth into the rat tibial fracture callus.

1995 • 48 citations

Growth-associated protein-43 and protein gene-product 9.5 innervation in human pancreas: changes in chronic pancreatitis

1994 • 47 citations

A novel calmodulin antagonist, CGS 9343B, modulates calcium-dependent changes in neurite outgrowth and growth cone movements

1991 • 47 citations

The Making of the nervous system

1988 • 47 citations

Role of highly conserved pyrimidine-rich sequences in the 3′ untranslated region of the GAP-43 mRNA in mRNA stability and RNA-protein interactions

1996 • 47 citations

Ultrastructural double localization of B-50/GAP43 and synaptophysin (p38) in the neonatal and adult rat hippocampus

1990 • 46 citations

Influence of peripheral nerve grafts on the expression of GAP-43 in regenerating retinal ganglion cells in adult hamsters

1995 • 46 citations

Kinase requirement for retinal growth cone motility

1994 • 46 citations

Expression of a 48‐Kilodalton Growth‐Associated Protein in the Goldfish Retina

1987 • 46 citations

An amino-terminal domain of the growth-associated protein gap-43 mediates its effects on filopodial formation and cell spreading

1994 • 46 citations

Muscarinic receptor activation stimulates B-50/GAP43 phosphorylation in isolated nerve growth cones

1989 • 46 citations

Studies on the Role of B‐50 (GAP‐43) in the Mechanism of Ca²⁺‐Induced Noradrenaline Release: Lack of Involvement of Protein Kinase C After the Ca²⁺ Trigger

1993 • 44 citations

Neuronal markers, peptides and enzymes in nerves and chromaffin cells in the rat adrenal medulla during postnatal development

1994 • 44 citations

The expression of GAP-43 and synaptophysin in the developing rat retina

1994 • 44 citations

B‐50/GAP‐43 Binds to Actin Filaments Without Affecting Actin Polymerization and Filament Organization

1993 • 44 citations

B-50/GAP-43 expression by the olfactory receptor cells and the neurons migrating from the olfactory placode in embryonic rats

1994 • 43 citations

On the formation of neuromata in the primtary olfactory projection

1994 • 43 citations

Ligand-induced growth cone collapse: amplification and blockade by variant GAP-43 peptides

1995 • 43 citations

The maximum rate of neurofilament transport in axons: a view of molecular transport mechanisms continuously engaged

1993 • 43 citations

Cross‐Reaction of Anti‐Rat B‐50: Characterization and Isolation of a “B‐50 Phosphoprotein” from Bovine Brain

1984 • 43 citations

Developmental study of the expression of B50/GAP‐43 in rat retina

1993 • 43 citations

Changes in Axonal Flow during Regeneration of Mammalian Motor Nerves

1971 • 43 citations

Analysis of the Role of Calmodulin Binding and Sequestration in Neuromodulin (GAP-43) Function

1996 • 42 citations

Immunolocalization of B-50 (GAP-43) in the mouse olfactory bulb: Predominant presence in preterminal axons

1992 • 42 citations

Estrogen and androgen differentially modulate the growth-associated protein GAP-43 (neuromodulin) messenger ribonucleic acid in postnatal rat brain.

1994 • 41 citations

4‐Aminopyridine Stimulates B‐50 (GAP43) Phosphorylation and [³H]Noradrenaline Release in Rat Hippocampal Slices

1990 • 41 citations

De novo synthesis of GAP-43: in situ hybridization histochemistry and light and electron microscopy immunocytochemical studies in regenerating motor neurons of cranial nerve nuclei in the rat brain

1994 • 41 citations

Phosphorylase kinase phosphorylates the calmodulin-binding regulatory regions of neuronal tissue-specific proteins B-50 (GAP-43) and neurogranin.

1993 • 40 citations

Distribution of GAP-43 mRNA in the immature and adult cerebellum: a role for GAP-43 in cerebellar development and neuroplasticity

1996 • 40 citations

Chicken growth-associated protein (GAP)-43: primary structure and regulated expression of mRNA during embryogenesis

1990 • 40 citations

Neuromodulin (GAP-43) Can Regulate a Calmodulin-Dependent Target in vitro

1994 • 40 citations

Light and electron microscopic localization of B‐50 (GAP43) in the rat spinal cord during transganglionic degenerative atrophy and regeneration

1992 • 40 citations

Neither laminin nor prior optic nerve section are essential for the regeneration of adult mammalian retinal ganglion cell axonsin vitro

1988 • 40 citations

The Molecular Basis of Development

1985 • 40 citations

Mutation of Serine 41 in the Neuron‐Specific Protein B‐50 (GAP‐43) Prohibits Phosphorylation by Protein Kinase C

1990 • 39 citations

B‐50 (GAP‐43) in the spinal cord caudal to hemisection: Indication for lack of intraspinal sprouting in dorsal root axons

1993 • 39 citations

Axotomy accelerates slow component b of axonal transport

1991 • 39 citations

Cloning and Characterization of the Rat Gene Encoding GAP‐43

1990 • 39 citations

Expression of the growth-associated protein B-50/GAP43 via a defective herpes-simplex virus vector results in profound morphological changes in non-neuronal cells

1994 • 38 citations

ADP‐Ribosylation of the Neuronal Phosphoprotein B‐50/GAP‐43

1993 • 38 citations

Increased levels of GAP-43 protein in schizophrenic brain tissues demonstrated by a novel immunodetection method

1995 • 38 citations

Anti-NGF treatment blocks the upregulation of NGF receptor mRNA expression associated with collateral sprouting of rat dorsal root ganglion neurons

1995 • 38 citations

Vibrissectomy induced changes in GAP‐43 immunoreactivity in the adult rat barrel cortex

1992 • 38 citations

Accelerated Differentiation in Response to Retinoic Acid After Retrovirally Mediated Gene Transfer of GAP‐43 into Mouse Neuroblastoma Cells

1992 • 38 citations

Evidence for a Role of Protein Kinase C Substrate B‐50 (GAP‐43) in Ca²⁺‐Induced Neuropeptide Cholecystokinin‐8 Release from Permeated Synaptosomes

1993 • 38 citations

GAP‐43 gene expression is increased in anterior horn cells of amyotrophic lateral sclerosis

1992 • 37 citations

Regulation of Free Calmodulin Levels in Neurons by Neuromodulin: Relationship to Neuronal Growth and Regeneration

1990 • 37 citations

igloo, a GAP-43-related gene expressed in the developing nervous system of Drosophila

1994 • 37 citations

Possible Role of GAP‐43 in Calcium Regulation/Neurotransmitter Release^a

1991 • 36 citations

Phosphorylation of GAP-43 (growth-associated protein of 43 kDa) by conventional, novel and atypical isotypes of the protein kinase C gene family: differences between oligopeptide and polypeptide phosphorylation

1996 • 36 citations

Human GAP-43 Gene Expression: Multiple Start Sites for Initiation of Transcription in Differentiating Human Neuroblastoma Cells

1993 • 36 citations

Reduced Expression of the Molecular Markers of Dopaminergic Neuronal Atrophy in the Aging Rat Brain

1995 • 35 citations

Signaling Pathway Downstream of GABA_A Receptor in the Growth Cone

1996 • 35 citations

GAP-43 mRNA expression in early development of human nervous system

1996 • 35 citations

Electron microscopic immunocytochemistry of GAP-43 within proximal and chronically denervated distal stumps of transected peripheral nerve

1992 • 35 citations

Chapter 4 Phosphoprotein B-50: localization and function

1986 • 35 citations

Selective decline in protein F1 phosphorylation in hippocampus of senescent rats

1988 • 35 citations

Protein F1/GAP-43 and PKC gene expression patterns in hippocampus are altered 1–2 h after LTP

1995 • 34 citations

Partial denervation of the medial gastrocnemius muscle results in growth-associated protein-43 immunoreactivity in sprouting axons and schwann cells

1993 • 34 citations

The expression of B-50/GAP-43 during development of rat sinal neurons in culture is regulated by interneuronal contact

1990 • 34 citations

Inhibition of protein kinase C- and casein kinase II-mediated phosphorylation of GAP-43 by S100β

1994 • 34 citations

GAP 43-like immunoreactivity in normal adult rat sciatic nerve, spinal cord, and motoneurons: Axonal transport and effect of spinal cord transection

1993 • 33 citations

Isolation and Characterization of Rapid Transport Vesicle Subtypes from Rabbit Optic Nerve

1991 • 33 citations

The growth-associated neuronal phosphoprotein B-50: Improved purification, partial primary structure, and characterization and localization of proteolysis products

1988 • 32 citations

Mutagenesis of ser41 to ala inhibits the association of GAP-43 with the membrane skeleton of GAP-43-deficient PC12B cells: Effects on cell adhesion and the composition of neurite cytoskeleton and membrane

1996 • 32 citations

B-50/GAP-43 in neuronal development and repair

1990 • 32 citations

Neuronal Man: The Biology of Mind

1987 • 31 citations

B-50/GAP43 localization in polarized hippocampal neurons in vitro: An ultrastructural quantitative study

1992 • 31 citations

Increase in GAP‐43 and GFAP immunoreactivity int the rat hippocampus subsequent to perforant path kindling

1995 • 31 citations

GAP-43 and p75NGFR immunoreactivity in presynaptic cells following neuromuscular blockade by botulinum toxin in rat

1994 • 30 citations

Efficient adenoviral vector-directed expression of a foreign gene to neurons and sustentacular cells in the mouse olfactory neuroepithelium

1996 • 30 citations

ADP‐Ribosylation of Brain Neuronal Proteins Is Altered by In Vitro and In Vivo Exposure to Inorganic Mercury

1994 • 30 citations

Elevated expression of B‐50 (GAP‐43)‐mRNA in a subpopulation of olfactory bulb mitral cells following axotomy

1993 • 29 citations

Ultrastructural localization of adrenocorticotrophic hormone and the phosphoprotein B-50/growth-associated protein 43 in freeze-substituted, Lowicryl HM20-embedded mesencephalic central gray substance of the rat

1991 • 29 citations

Prolonged alteration in E-box binding after a single systemic kainate injection: potential relation to F1/GAP-43 gene expression

1996 • 29 citations

Neuronal protein GAP-43 is a member of novel group of brain acid-soluble proteins (BASPs)

1994 • 29 citations

Nerve growth factor stimulates GAP‐43 expression in PC12 cell clones independently of neurite outgrowth

1993 • 29 citations

Differential expression of growth-associated protein (GAP-43) mRNA in rat primary sensory neurons after peripheral nerve lesion: a non-radioactive in situ hybridisation study

1992 • 28 citations

Substance P‐, calcitonin gene‐related peptide, growth‐associated protein‐43, and neurotrophin receptor‐like immunoreactivity associated with unmyelinated axons in feline ventral roots and pia mater

1994 • 28 citations

GAP-43 (B50/F1) gene regulation by axonal injury of the hypoglossal nerve in the adult rat

1994 • 28 citations

Redistribution of B-50/growth-associated protein 43 during differentiation and maturation of rat hippocampal neurons In vitro

1992 • 28 citations

Characterization of Infant Rat Cerebral Cortical Membrane Proteins Phosphorylated In Vivo: Identification of the ACTH‐Sensitive Phosphoprotein B‐50

1982 • 27 citations

Redistribution of GAP-43 during growth cone developmentin vitro; immunocytochemical studies

1991 • 27 citations

Growth-associated Protein-43 (GAP-43) Facilitates Peptide Hormone Secretion in Mouse Anterior Pituitary AtT-20 Cells

1996 • 27 citations

Transient expression of GAP-43 in nonneuronal cells of the embryonic chicken limb

1992 • 27 citations

Functional characterization of the rat GAP-43 promoter

1994 • 26 citations

Ultrastructural co-localization of calmodulin and B-50/growth-associated protein-43 at the plasma membrane of proximal unmyelinated axon shafts studied in the model of the regenerating rat sciatic nerve

1997 • 26 citations

Enhancement of Endogenous Release of Glutamate and γ‐Aminobutyric Acid from Hippocampus CA1 Slices After In Vivo Long‐Term Potentiation

1992 • 25 citations

Cat dental pulp after denervation and subsequent re-innervation: changes in blood-flow regulation and distribution of neuropeptide-, GAP-43- and low-affinity neurotrophin receptor-like immunoreactivity

1993 • 25 citations

Regulation of growth cone motility

1991 • 25 citations

Anatomic Distribution of the Growth-Associated Protein GAP-43 in the Developing Human Brainstem

1993 • 25 citations

Cloning and promoter analysis of the human B-50/GAP-43 gene

1995 • 24 citations

Development and differentiation of Schwann cells.

1996 • 24 citations

Palmitylation of neuromodulin (GAP-43) is not required for phosphorylation by protein kinase C.

1992 • 24 citations

TGF-βs and cAMP Regulate GAP-43 Expression in Schwann Cells and Reveal the Association of this Protein with the Trans-Golgi Network

1995 • 24 citations

Growth-associated protein (GAP-43)-like immunoreactivity in primary and permanent tooth pulp nerve fibers of the cat

1992 • 24 citations

Rapid purification, site-directed mutagenesis, and initial characterization of recombinant RC3/neurogranin

1994 • 24 citations

GAP‐43 mRNA in Mouse Motoneurons Undergoing Axonal Sprouting in Response to Muscle Paralysis or Partial Denervation

1996 • 24 citations

Rapid initiation of neurite outgrowth onto laminin from explants of adult mouse retina induced by optic nerve crush

1990 • 24 citations

Immunocytochemistry of B-50 (GAP-43) in the spinal cord and in dorsal root ganglia of the adult cat

1993 • 23 citations

B-50/GAP-43 phosphorylation in hippocampal slices from aged rats: Effects of phosphatidylserine administration

1993 • 23 citations

B-50 (GAP-43) Immunoreactivity Is Rarely Detected within Intact Catecholaminergic and Serotonergic Axons Innervating the Brain and Spinal Cord of the Adult Rat, but Is Associated with These Axons Following Lesion

1995 • 23 citations

Rapid axonal transport as a chromatographic process: The use of immunocytochemistry of ligated nerves to investigate the biochemistry of anterogradely versus retrogradely transported organelles

1988 • 23 citations

Appearance of neuropeptides and NADPH-diaphorase during development of the enteropancreatic innervation

1995 • 23 citations

The protein kinase C phosphosite(s) in B-50 (GAP-43) are confined to 15K phosphofragments produced by Staphylococcus aureus V8 protease

1989 • 23 citations

Immunocytochemical study of the differentiation process of the septal organ of Masera in developing rats

1995 • 23 citations

Molecular analysis of the function of the neuronal growth-associated protein GAP-43 by genetic intervention

1991 • 23 citations

Use of a two-hybrid system to investigate molecular interactions of GAP-43

1996 • 22 citations

Binding of the Neuronal Protein B-50, but Not the Metabolite B-60, to Calmodulin

1990 • 22 citations

Peptides in the gastrointestinal tract in human immunodeficiency virus infection

1992 • 22 citations

Changes in Protein Kinase C and its Presynaptic Substrate B‐SO/GAP‐43 after Intrauterine Exposure to Methylazoxy‐methanol, a Treatment Inducing Cortical and Hippocampal Damage and Cognitive Deficit in Rats

1995 • 22 citations

Calmodulin distribution in peripheral nerve: an EM immunocytochemical study

1988 • 22 citations

Turnover of brain postsynaptic densities after selective deafferentation: detection by means of an antibody to antigen PSD-95

1982 • 22 citations

Specific proteolysis of a brain membrane phosphoprotein (B-50): Effects of calcium and calmodulin

1982 • 21 citations

Serotonergic terminals express a growth associated protein (GAP-43) in the adult rat spinal cord

1994 • 21 citations

Involvement of Growth‐Associated Protein‐43 with Irreversible Neurite Outgrowth by Dibutyryl Cyclic AMP and Phorbol Ester in NG108–15 Cells

1992 • 21 citations

Distribution of GAP-43 in relation to CGRP and synaptic vesicle markers in rat skeletal muscles during development

1993 • 20 citations

Protein Phosphatases 1 and 2A Dephosphorylate B‐50 in Presynaptic Plasma Membranes from Rat Brain

1992 • 20 citations

Increase in Neurite Formation and Acetylene line Release by Transfection of Growth‐Associated Protein‐43 cDNA into NG108–15 Cells

1993 • 20 citations

GAP-43 and its relation to autonomic and sensory neurons in sciatic nerve and gastrocnemius muscle in the rat

1995 • 20 citations

B-50 (GAP-43) in Onuf's nucleus of the adult cat

1993 • 20 citations

Synaptophysin immunocytochemistry in the regenerating sprouts from the nodes of Ranvier in injured rat sciatic nerve

1993 • 20 citations

Developmental changes in B‐50 (GAP‐43) in primary cultures of cerebral cortex: B‐50 immunolocalization, axonal elongation rate and growth cone morphology

1991 • 20 citations

Spontaneous morphological changes by overexpression of the growth-associated protein B-50/GAP-43 in a PC12 cell line

1993 • 20 citations

Changes in the distribution of the neuron-specific B-50, neurofilament protein and glial fibrillary acidic proteins following an unilateral mesencephalic lesion in the rat

1988 • 19 citations

Peripheral target reinnervation following orthotopic grafting of fetal allogeneic and xenogeneic dorsal root ganglia

1995 • 19 citations

Dephosphorylation of B-50 in synaptic plasma membranes

1990 • 19 citations

In vivo induction of the growth associated protein GAP43/B-50 in rat astrocytes following transient middle cerebral artery occlusion

1994 • 19 citations

Innervation of the rat anterior and neurointermediate pituitary visualized by immunocytochemistry for the growth-associated protein GAP-43.

1994 • 18 citations

Altered phosphorylation of growth-associated protein B50/GAP-43 in Alzheimer disease with high neurofibrillary tangle density.

1993 • 18 citations

Expression of GAP‐43 mRNA in Mouse Spinal Cord Following Unilateral Peripheral Nerve Damage: is There a Contralateral Effect?

1993 • 18 citations

Monoclonal Antibody NM2 Recognizes the Protein Kinase C Phosphorylation Site in B‐50 (GAP‐43) and in Neurogranin (BICKS)

1994 • 18 citations

Developmental and environmental changes in GAP-43 gene expression in cat visual cortex

1993 • 18 citations

Changes in innervation of long bones after insertion of an implant: Immunocytochemical study in goats with antibodies to calcitonin gene‐related peptide and B‐50/GAP‐43

1995 • 18 citations

The growth-associated protein B-50 (GAP-43) in dystrophic neurites extending into Alzheimer's plaques

1993 • 17 citations

Microencephaly reduces the phosphorylation of the PKC substrate B-50/GAP43 in rat cortex and hippocampus

1991 • 17 citations

Expression of GAP-43 (neuromodulin) during the development of the rat adrenal gland.

1994 • 17 citations

Altered GAP-43 Immunoreactivity in Regenerating Sciatic Nerve of Diabetic Rats

1996 • 17 citations

Estrogen and androgen differentially modulate the growth-associated protein GAP-43 (neuromodulin) messenger ribonucleic acid in postnatal rat brain

1994 • 17 citations

Differences in the Distribution of Cytochrome b₅₆₁ and Synaptophysin in Dog Splenic Nerve: A Biochemical and Immunocytochemical Study

1994 • 17 citations

Immunocytochemical localization of a growth-associated protein (GAP-43) in rat adrenal gland

1994 • 17 citations

B-50/GAP43 localization on membranes of putative transport vesicle in the cell body, neurites and growth cones of cultured hippocampal neurons

1992 • 17 citations

Evidence for a Role of Calmodulin in Calcium‐Induced Noradrenaline Release from Permeated Synaptosomes: Effects of Calmodulin Antibodies and Antagonists

1996 • 17 citations

B-50/growth-associated protein-43, a marker of neural development inXenopus laevis

1997 • 16 citations

Upregulation of B-50/GAP-43 in Schwann cells at denervated motor endplates and in motoneurons after rat facial nerve crush

1993 • 16 citations

On the Distribution of GAP‐43 and its Relation to Serotonin in Adult Monkey and Cat Spinal Cord and Lower Brainstem

1992 • 16 citations

Ventral root avulsion versus transection at the cervical 7 level of the cat spinal cord

1993 • 16 citations

B-50 (GAP-43) in the rat spinal cord caudal to hemisection: lack of intraspinal sprouting by dorsal root axons

1995 • 16 citations

Developmental changes in B‐50 (GAP‐43) in primary cultures of cerebral cortex: Content and phosphorylation of B‐50

1991 • 15 citations

Purification of the growth-associated protein GAP-43 by reversed phase chromatography: amino acid sequence analysis and cDNA identification

1990 • 15 citations

Passive avoidance learning induced change in GAP43 phosphorylation in day-old chicks

1995 • 15 citations

Determination of the endogenous phosphorylation state of B‐50/GAP‐43 and neurogranin in different brain regions by electrospray mass spectrometry

1996 • 15 citations

Immunohistochemical localization of GAP-43 in rat and human sympathetic nervous system — effects of aging and diabetes

1991 • 15 citations

Inhibition of neurite outgrowth following intracellular delivery of anti-GAP-43 antibodies depends upon culture conditions and method of neurite induction

1995 • 15 citations

GAP-43-like immunoreactivity in the adult retina of several species

1991 • 15 citations

Differential expression of GAP-43 mRNA in adult central cholinergic neuronal populations

1994 • 15 citations

Immunocytochemical localization of growth-associated protein GAP-43 in early human development

1995 • 15 citations

Ultrastructural immunolocalization of GAP-43 in the sprouted mossy fibres of kainic acid lesioned rats

1994 • 14 citations

Noradrenergic and cholinergic reinnervation of islet grafts in diabetic rats

1996 • 14 citations

The increase in B‐50/GAP‐43 in regenerating rat sciatic nerve occurs predominantly in unmyelinated axon shafts: A quantitative ultrastructural study

1995 • 14 citations

Expression levels of B-50/GAP-43 in PC12 cells are decisive for the complexity of their neurites and growth cones

1995 • 14 citations

N-terminal cysteines essential for Golgi sorting of B-50 (GAP-43) in PC12 cells

1995 • 14 citations

Does GAP-43 support axon growth by increasing the axonal transport velocity of calmodulin?

1992 • 14 citations

Selective alteration in B-50/GAP-43 phosphorylation in brain areas of animals characterized by cognitive impairment

1993 • 14 citations

GAP-43 mRNA suppression by the ribozyme in PC12 cells and inhibition of evoked dopamine release

1995 • 13 citations

Structure of the human gene for the neural phosphoprotein B-50 (GAP-43)

1993 • 13 citations

Increase of B-50/GAP-43 immunoreactivity in uninjured muscle nerves of mdx mice

1996 • 13 citations

Interactions between afferents to the dentate gyrus after entorhinal lesion during development: long-term regulation of choline acetyl-transferase activity

1978 • 13 citations

Effects of Gangliosides GM1 and GD1 a on GAP‐43 Phosphorylation and Dephosphorylation in Isolated Growth Cones

1994 • 13 citations

Delivery of Anti-Gap-43 Antibodies into Neuroblastoma Cells Reduces Growth Cone Size

1994 • 13 citations

Growth-associated protein 43 is down-regulated in cultured astrocytes

1989 • 13 citations

Developmental expression of the gene encoding growth‐associated protein 43 (GAP43) in the brains of normal and aneuploid mice

1991 • 13 citations

Regional Distribution of Amyloid β‐Protein Precursor, Growth‐associated Phosphoprotein‐43 and Microtubule‐associated Protein 2 Messenger RNAs in the Nigrostriatal System of Normal and Weaver Mutant Mice and Effects of Ventral Mesencephalic Grafts

1993 • 13 citations

Activation of protein kinase C by 4-aminopyridine dependent on Na+ channel activity in rat hippocampal slices

1989 • 13 citations

The Distribution of GAP-43 Immunoreactivity in the Central Nervous System of Adult Opossums <i>(Didelphis virginiana) </i>with Notes on their Development

1995 • 12 citations

Colchicine effect on B-50/GAP43 phosphoprotein localization in rat dorsal root ganglion explants

1989 • 12 citations

Identification of a kDa chick brain membrane protein showing changes phosphorylation after passive avoidance training

1990 • 11 citations

Cloning and embryonic expression ofXenopus laevis GAP-43 (XGAP-43)

1995 • 11 citations

Ultrastructural and cytochemical identification of apoptotic cell death accompanying development of the fetal rat olfactory nerve layer

1996 • 11 citations

Ultrastructural localization of B-50/growth-associated protein-43 to anterogradely transported synaptophysin-positive and calcitonin gene-related peptide-negative vesicles in the regenerating rat sciatic nerve

1996 • 11 citations

Phosphorylation of the Casein Kinase II Domain of B‐50 (GAP‐43) in Rat Cortical Growth Cones

1997 • 11 citations

Specific monoclonal antibodies against normal microtubule-associated protein-2 (MAP2) epitopes present in Alzheimer pathological structures do not recognize paired helical filaments

1992 • 11 citations

Purification of B-50 by 2-mercaptoethanol extraction from rat brain synaptosomal plasma membranes

1993 • 11 citations

Ultrastructural evidence for the lack of co-transport of B-50/GAP-43 and calmodulin in myelinated axons of the regenerating rat sciatic nerve

1996 • 10 citations

Expression of GAP43 mRNA in normally developing and transplanted neurons from the rat ventral mesencephalon

1994 • 10 citations

Characterization of two plasma membrane proteins abundant in rat brain

1987 • 10 citations

B-50 Phosphorylation, Protein Kinase C and the Induction of Excessive Grooming Behavior in the Rat

1987 • 10 citations

Detergents and Peptides Alter Proteolysis and Calmodulin Binding of B‐50/GAP‐43 In Vitro

1994 • 10 citations

Immunolocalization of B-50 (GAP-43) in intact and lesioned neurohypophysis of adult rats

1995 • 9 citations

Evidence for multisite ADP-ribosylation of neuronal phosphoprotein B-50/GAP-43

1995 • 9 citations

Neonatal sciatic nerve lesion triggers the sprouting of fibers in the contralateral ventral root of the rat

1993 • 9 citations

Phosphorylation of MARCKS, neuromodulin, and neurogranin by protein kinase C exhibits differential responses to diacylglycerols

1995 • 8 citations

Lesion‐specific pattern of immunocytochemical distribution of growth‐associated protein B‐50 (GAP‐43) in the cerebellum of weaver and PCD‐mutant mice: Lack of B‐50 involvement in neuroplasticity of Purkinje cell terminals?

1994 • 8 citations

B-50/GAP-43 mRNA expression in cultured primary Schwann cells is regulated by cyclic AMP

1994 • 8 citations

The rat B-50(GAP43) promoter directs neural-preferred expression of a reporter gene in xenopus laevis embryos

1993 • 7 citations

Limited responses of neuronal mRNAs to unilateral lesions of the rat entorhinal cortex

1995 • 7 citations

Innervation of the rat anterior and neurointermediate pituitary visualized by immunocytochemistry for the growth-associated protein GAP- 43

1994 • 7 citations

Correlation of GAP-43 immunoreactivity with subpopulations of chromaffin cells in rat adrenal medulla

1993 • 7 citations

The development of daytime rearing behavior in methylazoxymethanol-treated rats: Methodological considerations

1987 • 7 citations

GAP43 identifies developing muscle cells in human embryos

1993 • 7 citations

Chapter 3: Selective phosphorylation and dephosphorylation of the protein B-50

1991 • 7 citations

Microheterogeneity of the growth-associated neuronal protein B-50 (GAP-43)

1989 • 6 citations

Developmental expression of GAP43 mRNA in chromaffin cells and intraadrenal neurons

1995 • 6 citations

Reduced electrical excitability of PC12 cells deficient in GAP-43: comparison with GAP-43-positive cells

1995 • 5 citations

Rat B-50 gene transcription and translation

1995 • 5 citations

Light microscopy study of low-affinity nerve growth factor receptor and phosphoprotein B-50/neuromodulin in inflammatory myopathies

1996 • 5 citations

Ultrastructural examination of B-50(GAP-43) immunoreactivity in rat jejunal villi

1995 • 5 citations

Colchicine induces the GAP-43 gene expression in rat hypothalamus

1995 • 5 citations

Antibodies directed to the calmodulin-binding domain of B-50 (gap-43) inhibit Ca2+-induced dopamine release from permeated synaptosomes

1996 • 3 citations

Production and characterization of antibodies against C-terminal peptide of protein F1: A novel phosphorylation at serine 209 of the peptide by protein kinase C

1994 • 3 citations

Altered GAP-43 immunoreactivity in regenerating sciatic nerve of diabetic rats

1996 • 3 citations

Characterization of MSH/ACTH-like immunoreactivity in sciatic nerves of Xenopus laevis by immunocytochemistry, Western blotting and radioimmunoassay

1990 • 2 citations

Endogenous ADP-Ribosylation of Phosphoprotein B-50/GAP-43 and other Neuronal Substrates

1997 • 2 citations

The expression of rat GAP-43 cDNA in transgenic carp

1993 • 1 citations

Science's new language

1993 • 1 citations

Deleted Work

1955 • 0 citations