Synaptic Vesicles and Exocytosis

Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C

1992 • 4,480 citations

Membrane Fusion

1990 • 2,458 citations

The Fine Structure of the Nervous System.

1970 • 1,971 citations

Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin

1992 • 1,792 citations

A novel arachidonic acid-selective cytosolic PLA2 contains a Ca2+-dependent translocation domain with homology to PKC and GAP

1991 • 1,709 citations

Syntaxin: A Synaptic Protein Implicated in Docking of Synaptic Vesicles at Presynaptic Active Zones

1992 • 1,274 citations

Microdomains of High Calcium Concentration in a Presynaptic Terminal

1992 • 837 citations

Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C

1990 • 829 citations

Optical Analysis of Synaptic Vesicle Recycling at the Frog Neuromuscular Junction

1992 • 766 citations

Identification of a transmembrane glycoprotein specific for secretory vesicles of neural and endocrine cells.

1985 • 716 citations

Clathrin, Adaptors, and Sorting

1990 • 704 citations

Neurexins: Synaptic Cell Surface Proteins Related to the α-Latrotoxin Receptor and Laminin

1992 • 669 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

Calcium ions, active zones and synaptic transmitter release

1988 • 609 citations

Structure and function of vacuolar class of ATP-driven proton pumps

1989 • 600 citations

A cDNA that suppresses MPP+ toxicity encodes a vesicular amine transporter

1992 • 594 citations

Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans

1991 • 567 citations

Sequence similarity of phospholipase C with the non-catalytic region of src

1988 • 541 citations

Synapsins: Mosaics of Shared and Individual Domains in a Family of Synaptic Vesicle Phosphoproteins

1989 • 535 citations

Cellubrevin is a ubiquitous tetanus-toxin substrate homologous to a putative synaptic vesicle fusion protein

1993 • 504 citations

The C. elegans genome sequencing project: a beginning

1992 • 496 citations

rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.

1990 • 486 citations

Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae.

1990 • 474 citations

VESICLE-MEDIATED PROTEIN SORTING

1992 • 472 citations

Mechanism of Transport and Storage of Neurotransmitter

1987 • 471 citations

Spontaneous release of transmitter from growth cones of embryonic neurones

1983 • 436 citations

A yeast gene encoding a protein homologous to the human c-has/bas proto-oncogene product

1983 • 396 citations

The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

1989 • 387 citations

Vesicle hypothesis of the release of quanta of acetylcholine.

1980 • 364 citations

Identification of Synaptophysin as a Hexameric Channel Protein of the Synaptic Vesicle Membrane

1988 • 356 citations

Domain structure of synaptotagmin (p65)

1991 • 350 citations

Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.

1991 • 347 citations

Tetanus toxin action: Inhibition of neurotransmitter release linked to synaptobrevin proteolysis

1992 • 340 citations

Exo-endocytotic recycling of synaptic vesicles in developing processes of cultured hippocampal neurons

1992 • 336 citations

A Synaptic Vesicle Protein with a Novel Cytoplasmic Domain and Four Transmembrane Regions

1987 • 326 citations

Two Vesicle-associated Membrane Protein Genes Are Differentially Expressed in the Rat Central Nervous System

1989 • 326 citations

Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport

1988 • 323 citations

Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling.

1992 • 321 citations

Autoantibodies to a 128-kd Synaptic Protein in Three Women with the Stiff-Man Syndrome and Breast Cancer

1993 • 310 citations

Synaptic vesicle-associated Ca2+/calmodulin-dependent protein kinase II is a binding protein for synapsin I

1992 • 299 citations

Molecular characterization of synaptophysin, a major calcium-binding protein of the synaptic vesicle membrane.

1986 • 296 citations

Calcium Channels Coupled to Glutamate Release Identified by ω-Aga-IVA

1992 • 292 citations

cDNA sequence encoding the 16-kDa proteolipid of chromaffin granules implies gene duplication in the evolution of H+-ATPases.

1988 • 288 citations

Protein-Mediated Membrane Fusion

1989 • 279 citations

Cloning and sequence analysis of cDNA for a neuronal cell membrane antigen, HPC-1.

1992 • 276 citations

HPC-1 is associated with synaptotagmin and omega-conotoxin receptor.

1992 • 275 citations

The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase.

1992 • 258 citations

The synaptic vesicle protein SV2 is a novel type of transmembrane transporter

1992 • 257 citations

SV2, a Brain Synaptic Vesicle Protein Homologous to Bacterial Transporters

1992 • 244 citations

Isolation of genes encoding the Neurospora vacuolar ATPase. Analysis of vma-1 encoding the 67-kDa subunit reveals homology to other ATPases.

1988 • 236 citations

Nucleotide and deduced amino acid sequences of a GTP-binding protein family with molecular weights of 25,000 from bovine brain.

1988 • 234 citations

A role for synaptotagmin (p65) in regulated exocytosis

1993 • 233 citations

Epimorphin: A mesenchymal protein essential for epithelial morphogenesis

1992 • 222 citations

The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen.

1992 • 220 citations

Selectively amplified expression of an isoform of the vacuolar H(+)-ATPase 56-kilodalton subunit in renal intercalated cells.

1992 • 212 citations

Kinetic analysis of secretion from permeabilized adrenal chromaffin cells reveals distinct components.

1992 • 208 citations

Synaptophysin: molecular organization and mRNA expression as determined from cloned cDNA.

1987 • 205 citations

Cloning of a Rab3 isotype predominantly expressed in adipocytes.

1992 • 203 citations

Exocytosis from Neuronal Large Dense-Cored Vesicles

1990 • 196 citations

Synaptic Vesicle Ceramide Kinase

1989 • 195 citations

Amphiphysin, a novel protein associated with synaptic vesicles.

1992 • 192 citations

Structure and function of the synapsins.

1992 • 192 citations

GABA and glycine in synaptic vesicles: storage and transport characteristics

1991 • 191 citations

Transmitter release from synapses: Does a preassembled fusion pore initiate exocytosis?

1990 • 186 citations

Conformational change and localization of calpactin I complex involved in exocytosis as revealed by quick-freeze, deep-etch electron microscopy and immunocytochemistry.

1990 • 179 citations

Uptake of GABA by rat brain synaptic vesicles isolated by a new procedure.

1988 • 174 citations

Interaction of free and synaptic vesicle-bound synapsin I with F-actin

1992 • 167 citations

The vesicular acetylcholine transport system

1987 • 167 citations

Molecular cloning, primary structure, and orientation of the vertebrate photoreceptor cell protein peripherin in the rod outer segment disk membrane

1990 • 162 citations

The progenitor of ATP synthases was closely related to the current vacuolar H⁺‐ATPase

1989 • 161 citations

The phosphorylation of kinesin regulates its binding to synaptic vesicles.

1992 • 156 citations

α-latrotoxin and related toxins

1989 • 153 citations

Cellular And Molecular Biology Of The Presynaptic Nerve Terminal

1991 • 150 citations

Protein tyrosine phosphorylation in synaptic vesicles.

1988 • 148 citations

cDNA sequence and homologies of the “57-kDa” nucleotide-binding subunit of the vacuolar ATPase from Arabidopsis.

1988 • 148 citations

Structures and chromosomal localizations of two human genes encoding synaptobrevins 1 and 2.

1990 • 144 citations

A Conserved Gene Encoding the 57-kDa Subunit of the Yeast Vacuolar H+-ATPase

1989 • 144 citations

Uptake of γ‐Aminobutyric Acid by a Synaptic Vesicle Fraction Isolated from Rat Brain

1988 • 134 citations

SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes.

1992 • 133 citations

Isolation of vacuolar membrane H(+)-ATPase-deficient yeast mutants; the VMA5 and VMA4 genes are essential for assembly and activity of the vacuolar H(+)-ATPase.

1993 • 127 citations

Synaptoporin, a novel putative channel protein of synaptic vesicles

1990 • 127 citations

Clathrin assembly protein AP180: primary structure, domain organization and identification of a clathrin binding site.

1993 • 118 citations

Human endomembrane H+ pump strongly resembles the ATP-synthetase of Archaebacteria.

1989 • 116 citations

Dissociation, cross-linking, and glycosylation of the coated vesicle proton pump.

1990 • 114 citations

The role of coated vesicles in recycling of synaptic vesicle membrane

1989 • 106 citations

The structure of cytochrome b561, a secretory vesicle-specific electron transport protein.

1988 • 102 citations

A 15 kDa proteolipid found in mediatophore preparations from Torpedo electric organ presents high sequence homology with the bovine chromaffin granule protonophore

1990 • 101 citations

Isolation and sequence of a cDNA clone encoding the 31-kDa subunit of bovine kidney vacuolar H+-ATPase.

1988 • 101 citations

rab3A attachment to the synaptic vesicle membrane mediated by a conserved polyisoprenylated carboxy-terminal sequence

1991 • 99 citations

The patch-clamp technique in the study of secretion

1989 • 97 citations

Synaptic Vesicle Traffic: Rush Hour in the Nerve Terminal

1993 • 95 citations

Clathrin light chains: arrays of protein motifs that regulate coated-vesicle dynamics

1991 • 94 citations

Clathrin-associated proteins of bovine brain coated vesicles. An analysis of their number and assembly-promoting activity.

1992 • 89 citations

Synapsin I-mediated interaction of brain spectrin with synaptic vesicles.

1991 • 86 citations

Specific association of the proto-oncogene product pp60c-src with an intracellular organelle, the PC12 synaptic vesicle

1992 • 76 citations

A single gene encodes the catalytic “A” subunit of the bovine vacuolar H(+)-ATPase.

1991 • 75 citations

A ubiquitous 64-kDa protein is a component of a chloride channel of plasma and intracellular membranes.

1992 • 73 citations

Ion channels in synaptic vesicles from Torpedo electric organ.

1988 • 71 citations

An mRNA from human brain encodes an isoform of the B subunit of the vacuolar H(+)-ATPase.

1990 • 66 citations

Complete coding sequences of therasrelatedrab3 and 4 cDNAs

1988 • 65 citations

Sodium cotransport proteins

1992 • 64 citations

Molecular cloning of cDNA encoding the C subunit of H(+)-ATPase from bovine chromaffin granules

1990 • 63 citations

Isolation and reconstitution of the chloride transporter of clathrin-coated vesicles

1989 • 56 citations

Four synaptic vesicle-specific proteins: identification by monoclonal antibodies and distribution in the nervous tissue and the adrenal medulla

1987 • 55 citations

Formation and modulation of chemical connections: Evoked acetylcholine release from growth cones and neurites of specific identified neurons

1989 • 53 citations

Evidence for an ascorbate shuttle for the transfer of reducing equivalents across chromaffin granule membranes.

1986 • 53 citations

Vacuolar proton pumps

1989 • 49 citations

Torpedo synaptophysin: evolution of a synaptic vesicle protein

1990 • 45 citations

Characterization of a novel synapse-specific protein. I. Developmental expression and cellular localization of the F1-20 protein and mRNA

1992 • 44 citations

Calmodulin is tightly associated with synaptic vesicles independent of calcium.

1984 • 39 citations

Multiple GTP-binding proteins from cholinergic synaptic vesicles

1990 • 36 citations

THE STRUCTURE OF CYTOCHROME C

1957 • 19 citations

A synaptic vesicle specific GTP-binding protein from ray electric organ

1991 • 19 citations

Molecular architecture of the nerve terminal

1991 • 16 citations