Axon guidance: A compelling case for repelling growth cones

Developmental mechanisms that generate precise patterns of neuronal connectivity

1993 • 1,435 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Collapsin: A protein in brain that induces the collapse and paralysis of neuronal growth cones

1993 • 1,146 citations

The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules

1993 • 930 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

The axonal chemoattractant netrin-1 is also a chemorepellent for trochlear motor axons

1995 • 566 citations

Inhibitors of Neurite Growth

1993 • 545 citations

Sernaphorin III can function as a selective chemorepellent to pattern sensory projections in the spinal cord

1995 • 492 citations

Avoidance of posterior tectal membranes by temporal retinal axons

1987 • 370 citations

Fasciclin IV: Sequence, expression, and function during growth cone guidance in the grasshopper embryo

1992 • 369 citations

Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension

1995 • 352 citations

Collapse of growth cone structure on contact with specific neurites in culture

1987 • 284 citations

Role of Intracellular Calcium in NI-35-Evoked Collapse of Neuronal Growth Cones

1993 • 271 citations

The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor.

1993 • 262 citations

Biochemical characterization of a putative axonal guidance molecule of the chick visual system

1990 • 241 citations

Localized collapsing cues can steer growth cones without inducing their full collapse

1995 • 241 citations

Semaphorin II can function as a selective inhibitor of specific synaptic arborizations

1995 • 200 citations

Guidance of cerebellofugal axons in the rat embryo: Directed growth toward the floor plate and subsequent elongation along the longitudinal axis

1995 • 100 citations

Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia

1993 • 99 citations

Chemorepulsion of developing motor axons by the floor plate

1995 • 98 citations

A common denominator of growth cone guidance and collapse?

1990 • 93 citations

Repulsive and inhibitory signals

1995 • 90 citations

Floor plate chemoattracts crossed axons and chemorepels uncrossed axons in the vertebrate brain

1995 • 71 citations