Monoclonal antibodies show that kinase C phosphorylation of GAP-43 during axonogenesis is both spatially and temporally restricted in vivo.

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Neurogenesis and neuron regeneration in the olfactory system of mammals. I. Morphological aspects of differentiation and structural organization of the olfactory sensory neurons

1979 • 983 citations

[1] Assays of protein kinase

1983 • 832 citations

Axonally transported proteins associated with axon growth in rabbit central and peripheral nervous systems

1981 • 583 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism, and synaptic plasticity

1987 • 543 citations

Growth-associated protein, GAP-43, a polypeptide that is induced when neurons extend axons, is a component of growth cones and corresponds to pp46, a major polypeptide of a subcellular fraction enriched in growth cones.

1986 • 526 citations

A Protein Induced During Nerve Growth (GAP-43) is a Major Component of Growth-Cone Membranes

1986 • 505 citations

Anatomical distribution of the growth-associated protein GAP-43/B-50 in the adult rat brain

1988 • 390 citations

Posttranslational membrane attachment and dynamic fatty acylation of a neuronal growth cone protein, GAP-43.

1989 • 383 citations

The expression of the growth associated protein B50/GAP43 in the olfactory system of neonatal and adult rats

1989 • 300 citations

The influence of basic residues on the substrate specificity of protein kinase C.

1987 • 287 citations

Distribution of protein kinase C-like immunoreactive neurons in rat brain

1988 • 278 citations

Interaction of protein kinase C with membranes is regulated by Ca2+, phorbol esters, and ATP.

1985 • 274 citations

Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion

1984 • 225 citations

Phosphorylation of B‐50 Protein by Calcium‐Activated, Phospholipid‐Dependent Protein Kinase and B‐50 Protein Kinase

1983 • 224 citations

Presynaptic localization of B-50 phosphoprotein: the (ACTH)-sensitive protein kinase substrate involved in rat brain polyphosphoinositide metabolism

1985 • 208 citations

Nerve growth cones isolated from fetal rat brain. III. Calcium- dependent protein phosphorylation

1985 • 185 citations

Comparison of the immunocytochemical distribution of the phosphoprotein B-50 in the cerebellum and hippocampus of immature and adult rat brain

1986 • 182 citations

Elevated synthesis of an axonally transported protein correlates with axon outgrowth in normal and injured pyramidal tracts

1986 • 182 citations

GAP-43 in growth cones is associated with areas of membrane that are tightly bound to substrate and is a component of a membrane skeleton subcellular fraction

1990 • 178 citations

Aging in the rat olfactory system: Correlation of changes in the olfactory epithelium and olfactory bulb

1981 • 178 citations

Identification of the protein kinase C phosphorylation site in neuromodulin

1990 • 164 citations

Distribution and phosphorylation of the growth-associated protein GAP- 43 in regenerating sympathetic neurons in culture

1988 • 162 citations

An electron-microscopic study of the termination of the afferent fibres to the olfactory bulb from the cerebral hemisphere

1970 • 135 citations

Growth Cone Motility and Guidance

1988 • 134 citations

B-50 phosphorylation and polyphosphoinositide metabolism in nerve growth cone membranes

1988 • 119 citations

Electron microscopic localization of type I protein kinase C in rat Purkinje cells

1988 • 118 citations

Evidence for a Single Protein Kinase C‐Mediated Phosphorylation Site in Rat Brain Protein B‐50

1989 • 109 citations

B-50/GAP43 is localized at the cytoplasmic side of the plasma membrane in developing and adult rat pyramidal tract

1989 • 96 citations

Substrate specificity of phospholipid/Ca2+-dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein.

1985 • 96 citations

The mammalian pineal gland, a survey

1976 • 95 citations

Ultrastructural immunocytochemical localization of B-50/GAP43, a protein kinase C substrate, in isolated presynaptic nerve terminals and neuronal growth cones

1989 • 93 citations

Molecular Properties of the Growth‐Associated Protein GAP‐43 (B‐50)

1987 • 80 citations

Microsequence analysis of peptides and proteins

1987 • 70 citations

Amino acid sequence of P-57, a neurospecific calmodulin-binding protein

1987 • 68 citations

Depolarization‐Induced Phosphorylation of the Protein Kinase C Substrate B‐50 (GAP‐43) in Rat Cortical Synaptosomes

1990 • 65 citations

Physicochemical and hydrodynamic characterization of P-57, a neurospecific calmodulin binding protein

1986 • 64 citations

Phosphorylation of protein B-50 (GAP-43) from adult rat brain cortex by casein kinase II

1988 • 58 citations

Muscarinic receptor activation stimulates B-50/GAP43 phosphorylation in isolated nerve growth cones

1989 • 46 citations

Electrophoretic Analysis of Axonally Transported Proteins in Toad Retinal Ganglion Cells

1981 • 33 citations

The growth-associated neuronal phosphoprotein B-50: Improved purification, partial primary structure, and characterization and localization of proteolysis products

1988 • 32 citations

Intracellular regulators of neuronal sprouting: II. Phosphorylation reactions in isolated growth cones

1987 • 31 citations

Growth at the growth cone

1989 • 19 citations

Assay of protein kinase C with an N-bromosuccinimide-cleavage fragment of histone H1

1985 • 17 citations

Purification of the growth-associated protein GAP-43 by reversed phase chromatography: amino acid sequence analysis and cDNA identification

1990 • 15 citations

The right way to go.

1987 • 3 citations