Selection for activation of a new variant surface glycoprotein gene expression site in Trypanosoma brucei can result in deletion of the old one

Continuous Cultivation of Trypanosoma brucei Blood Stream Forms in a Medium Containing a Low Concentration of Serum Protein without Feeder Cell Layers

1989 • 982 citations

ALTERED FIDELITY OF MITOTIC CHROMOSOME TRANSMISSION IN CELL CYCLE MUTANTS OF S. CEREVISIAE

1985 • 390 citations

Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission

1986 • 322 citations

Inactivation of transcription by UV irradiation of T. brucei provides evidence for a multicistronic transcription unit including a VSG gene

1987 • 307 citations

Control of gene expression in trypanosomes

1995 • 291 citations

The genes and transcripts of an antigen gene expression site from T. brucei

1989 • 257 citations

Antigenic variation in trypansosomes: Secrets surface slowly

1996 • 225 citations

The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei

1987 • 218 citations

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei.

1990 • 214 citations

Large deletions result from breakage and healing of P. falciparum chromosomes

1988 • 180 citations

Coordinate transcription of variant surface glycoprotein genes and an expression site associated gene family in Trypanosoma brucei

1985 • 171 citations

The role of transferrin-receptor variation in the host range of Trypanosoma brucei

1998 • 148 citations

A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei

1995 • 145 citations

A developmentally regulated position effect at a telomeric locus in Trypanosoma brucei

1995 • 139 citations

High frequency of antigenic variation inTrypanosoma brucei rhodesienseinfections

1989 • 136 citations

High-efficiency clonal growth of bloodstream- and insect-form Trypanosoma brucei on agarose plates.

1992 • 129 citations

Reconstitution of a surface transferrin binding complex in insect form Trypanosoma brucei.

1994 • 126 citations

Chromosome organization of the protozoan Trypanosoma brucei.

1990 • 114 citations

Procyclic acidic repetitive protein (PARP) genes located in an unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient DNA transfection of Trypanosoma brucei.

1990 • 112 citations

Two modes of activation of a single surface antigen gene of trypanosoma brucei

1984 • 110 citations

VSG gene expression site control in insect form Trypanosoma brucei.

1994 • 96 citations

Mechanisms of Antigenic Variation in Borrelia hermsii and African Trypanosomes

1995 • 94 citations

DNA Rearrangements Associated with Multiple Consecutive Directed Antigenic Switches in Trypanosoma brucei

1996 • 86 citations

Gene Conversions Mediating Antigenic Variation in Trypanosoma brucei Can Occur in Variant Surface Glycoprotein Expression Sites Lacking 70-Base-Pair Repeat Sequences

1997 • 86 citations

Control of VSG gene expression sites in Trypanosoma brucei

1998 • 86 citations

Cloning and characterization of chromosome breakpoints ofPlasmodium falciparum: breakage and new telomere formation occurs frequently and randomly in subtelomeric genes

1992 • 85 citations

Antigenic Variation in Trypanosomes

1983 • 83 citations

The relative significance of mechanisms of antigenic variation in African trypanosomes

1997 • 81 citations

Analysis of antigen switching rates inTrypanosoma brucei

1986 • 80 citations

Parasitism and chromosome dynamics in protozoan parasites: is there a connection?

1995 • 77 citations

Analysis of Trypanosoma brucei vsg expression site switching in vitro

1997 • 70 citations

Telomere exchange can be an important mechanism of Variant Surface Glycoprotein gene switching in Trypanosoma brucei

1996 • 70 citations

Stable Expression of Mosaic Coats of Variant Surface Glycoproteins in Trypanosoma brucei

1996 • 64 citations

Characterization of VSG gene expression site promoters and promoter-associated DNA rearrangement events.

1991 • 62 citations

DNA-mediated transformation of bloodstream-formTrypanosoma brucei

1993 • 60 citations

Genetic exchange in Trypanosoma brucei brucei: variable chromosomal location of housekeeping genes in different trypanosome stocks

1991 • 52 citations

Two simultaneously active VSG gene transcription units in a single trypanosoma brucei variant

1985 • 45 citations

Frequent Loss of the Active Site during Variant Surface Glycoprotein Expression Site Switching In Vitro in Trypanosoma brucei

1998 • 42 citations

Effects of excess centromeres and excess telomeres on chromosome loss rates.

1991 • 36 citations

Manipulation of the vsg co-transposed region increases expression-site switching in Trypanosoma brucei

1997 • 34 citations

The viral thymidine kinase gene as a tool for the study of mutagenesis in Trypanosoma brucei

1996 • 34 citations

A proposal for karyotype nomenclature in Trypanosoma brucei

1997 • 20 citations

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