Characterization of VSG gene expression site promoters and promoter-associated DNA rearrangement events.

Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing

1980 • 3,476 citations

Purification of Mouse Immunoglobulin Heavy‐Chain Messenger RNAs from Total Myeloma Tumor RNA

1980 • 2,696 citations

Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat ofTrypanosoma brucei

1975 • 917 citations

Cultivation in a semi-defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense.

1985 • 567 citations

Evidence for Trans splicing in trypanosomes

1986 • 486 citations

Antigenic variation in trypanosoma brucei analyzed by electrophoretic separation of chromosome-sized DNA molecules

1984 • 368 citations

Identification of human immunodeficiency virus sequences by using in vitro enzymatic amplification and oligomer cleavage detection

1987 • 358 citations

Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: Evidence for Trans splicing

1986 • 354 citations

Antigenic variation in trypanosomes

1978 • 329 citations

Programmed Gene Rearrangements Altering Gene Expression

1987 • 312 citations

Inactivation of transcription by UV irradiation of T. brucei provides evidence for a multicistronic transcription unit including a VSG gene

1987 • 307 citations

Tubulin genes are tandemly linked and clustered in the genome of trypanosoma brucei

1983 • 265 citations

The genes and transcripts of an antigen gene expression site from T. brucei

1989 • 257 citations

Transcripts coding for variant surface glycoproteins of Trypanosoma brucei have a short, identical exon at their 5′ end

1982 • 243 citations

Novel expression-linked copies of the genes for variant surface antigens in trypanosomes

1980 • 240 citations

Three small RNAs within the 10 kb trypanosome rRNA transcription unit are analogous to Domain VII of other eukaryotic 28S rRNAs

1986 • 237 citations

α-Amanitin-insensitive transcription of variant surface glycoprotein genes provides further evidence for discontinuous transcription in trypanosomes

1984 • 228 citations

The anatomy and transcription of a telomeric expression site for variant-specific surface antigens in T. brucei

1987 • 218 citations

The promoter for a variant surface glycoprotein gene expression site in Trypanosoma brucei.

1990 • 214 citations

Conformation independent molecular weight determinations of RNA by gel electrophoresis

1971 • 199 citations

Apparent discontinuous transcription of Trypanosoma brucei variant surface antigen genes

1984 • 193 citations

Genomic environment of the expression-linked extra copies of genes for surface antigens of Trypanosoma brucei resembles the end of a chromosome

1982 • 183 citations

RNA splicing is required to make the messenger RNA for a variant surface antigen in trypanosomes

1982 • 183 citations

Trypanosome mRNAs have unusual "cap 4" structures acquired by addition of a spliced leader.

1987 • 179 citations

Coordinate transcription of variant surface glycoprotein genes and an expression site associated gene family in Trypanosoma brucei

1985 • 171 citations

The 35-Nucleotide Spliced Leader Sequence Is Common to All Trypanosome Messenger RNA's

1986 • 164 citations

Trypanosome mRNAs share a common 5′ spliced leader sequence

1984 • 163 citations

Chromosome rearrangements in trypanosoma brucei

1984 • 161 citations

Antigenic variation in trypanosomes

1978 • 152 citations

Tandem repetition of the 5′ mini-exon of variant surface glycoprotein genes: A multiple promoter for VSG gene transcription?

1983 • 152 citations

Discontinuous synthesis of mRNA in trypanosomes.

1984 • 145 citations

Sequences homologous to the variant antigen mRNA spliced leader are located in tandem repeats and variable orphons in Trypanosoma brucei

1983 • 143 citations

Transcription of the procyclic acidic repetitive protein genes of Trypanosoma brucei.

1990 • 137 citations

Gene duplication and transposition linked to antigenic variation in Trypanosoma brucei.

1981 • 127 citations

Many trypanosome messenger RNAs share a common 5′ terminal sequence

1984 • 120 citations

Alpha-amanitin resistant transcription of protein coding genes in insect and bloodstream form Trypanosoma brucei.

1989 • 117 citations

Molecular biology of trypanosome antigenic variation

1985 • 114 citations

Chromosome organization of the protozoan Trypanosoma brucei.

1990 • 114 citations

Activation of the genes for variant surface glycoproteins 117 and 118 in Trypanosoma brucei

1983 • 113 citations

Procyclic acidic repetitive protein (PARP) genes located in an unusually small alpha-amanitin-resistant transcription unit: PARP promoter activity assayed by transient DNA transfection of Trypanosoma brucei.

1990 • 112 citations

Two modes of activation of a single surface antigen gene of trypanosoma brucei

1984 • 110 citations

The expression-linked copy of surface antigen gene in Trypanosoma is probably the one transcribed

1981 • 105 citations

Modification of telomeric DNA inTrypanosoma brucei;a role in antigenic variation?

1984 • 97 citations

Mature mRNAs ofTrypanosoma bruceipossess a 5′ cap acquired by discontinuous RNA synthesis

1985 • 95 citations

In vivo labelling of intermediates in the discontinuous synthesis of mRNAs in Trypanosoma brucei.

1987 • 92 citations

The common 5′ terminal sequence on trypanosome mRNAs: a target for anti-messenger oligodeoxynucleotides

1986 • 91 citations

A 5' spliced leader is added in trans to both alpha- and beta-tubulin transcripts in Trypanosoma brucei.

1985 • 88 citations

Putative Genes of a Variant-Specific Antigen Gene Transcription Unit in Trypanosoma brucei

1988 • 87 citations

Transcription of telomere repeats in protozoa.

1989 • 85 citations

VSG gene 118 is transcribed from a cotransposed pol I-like promoter

1987 • 82 citations

Antigenic variation in African trypanosomes by gene replacement or activation of alternate telomeres

1984 • 81 citations

The inactivation and reactivation of an expression-linked gene copy for a variant surface glycoprotein in Trypanosoma brucei.

1984 • 80 citations

Improved separation of chromosome-sized DNA fromTrypanosoma brucei, stock 427-60

1989 • 79 citations

Possible DNA modification in GC dinucleotides ofTrypanosoma bruceitelomeric sequences; relationship with antigen gene transcriptiond

1984 • 78 citations

Two mechanisms of expression of a predominant variant antigen gene of Trypanosoma brucei

1984 • 77 citations

Trypanosoma brucei: Posttranscriptional Control of the Variable Surface Glycoprotein Gene Expression Site

1989 • 76 citations

Direct analysis of the mini-exon donor RNA ofTrypanosoma brucei: detection of a novel cap structure also present in messenger RNA

1987 • 73 citations

Sequences homologous to variant antigen mRNA spliced leader in Trypanosomatidae which do not undergo antigenic variation

1984 • 66 citations

Molecular biology of trypanosome antigenic variation.

1985 • 65 citations

Trypanosoma brucei: a surface antigen mRNA is discontinuously transcribed from two distinct chromosomes.

1985 • 58 citations

Identification and sequence of genedicB:translation of the division inhibitor from an in-phase internal start

1988 • 57 citations

Characterization of the Trypanosoma brucei 5S ribosomal RNA gene and transcript: the 5S rRNA is a spliced-leader-independent species

1985 • 55 citations

Putative genes of a variant-specific antigen gene transcription unit in Trypanosoma brucei.

1988 • 51 citations

Characterization of the expression-linked gene copies of variant surface glycoprotein 118 in two independently isolated clones ofTrypanosoma brucel

1982 • 46 citations

Two simultaneously active VSG gene transcription units in a single trypanosoma brucei variant

1985 • 45 citations

Trypanosoma brucei: posttranscriptional control of the variable surface glycoprotein gene expression site.

1989 • 45 citations

Antigenic variation in African trypanosomes: DNA rearrangements program immune evasion

1984 • 44 citations

Frequent Independent Duplicative Transpositions Activate a Single VSG Gene

1987 • 42 citations

The contribution of chromosomal translocations to antigenic variation in Trypanosoma brucei

1984 • 35 citations

Antigenic variation in African trypanosomes: genetic recombination and transcriptional control of VSG genes.

1990 • 29 citations

The cap of both miniexon-derived RNA and mRNA of trypanosomes is 7-methylguanosine.

1988 • 28 citations

Structure of a telomeric expression site for variant specific surface antigens in Trypanosoma brucei

1990 • 28 citations

Physical identification of branched intron side-products of splicing in Trypanosoma brucei.

1988 • 26 citations

Isolation and mapping of Escherichia coli mutations conferring resistance to division inhibition protein DicB

1989 • 25 citations

Frequent independent duplicative transpositions activate a single VSG gene.

1987 • 23 citations

Stable variant-specific transcripts of the variant cell surface glycoprotein gene 1.8 expression site in Trypanosoma brucei.

1988 • 15 citations

Cloning and Characterization of a Variant Surface Glycoprotein Expression Site from Trypanosoma equiperdum

1986 • 12 citations

Re-expression of an inactivated variable surface glycoprotein gene in Trypanosoma equiperdum

1984 • 12 citations

The Cap of Both Miniexon-Derived RNA and mRNA of Trypanosomes Is 7-Methylguanosine

1988 • 10 citations

Detection of a possibletrans-splicing intermediate inTrypanosoma brucei

1988 • 5 citations