Serotonergic Genes and Suicidality

Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region

1996 • 5,154 citations

The American Journal of Human Genetics

1950 • 5,048 citations

5-HIAA in the Cerebrospinal Fluid

1976 • 1,430 citations

Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression, and chromosomal localization.

1993 • 883 citations

A Serotonin Transporter Gene Promoter Polymorphism (5-HTTLPR) and Prefrontal Cortical Binding in Major Depression and Suicide

2000 • 603 citations

The neurobiology of suicide

1998 • 475 citations

Autoradiographic Demonstration of Increased Serotonin 5-HT2 and β-Adrenergic Receptor Binding Sites in the Brain of Suicide Victims

1990 • 411 citations

Suicidality and 5-Hydroxyindoleacetic Acid Concentration Associated With a Tryptophan Hydroxylase Polymorphism

1994 • 378 citations

5-HT uptake sites and 5-HT2 receptors in brain of antidepressant-free suicide victims/depressives: increase in 5-HT2 sites in cortex and amygdala

1993 • 316 citations

THE BIOLOGY OF IMPULSIVITY AND SUICIDALITY

2000 • 314 citations

A Tryptophan Hydroxylase Gene Marker for Suicidality and Alcoholism

1998 • 305 citations

Major depression and the risk of attempted suicide

1995 • 300 citations

Cerebrospinal fluid amines and higher-lethality suicide attempts in depressed inpatients

1997 • 277 citations

Prediction of Level of Serotonin 2A Receptor Binding by Serotonin Receptor 2A Genetic Variation in Postmortem Brain Samples From Subjects Who Did or Did Not Commit Suicide

1999 • 274 citations

A family based association study of T102C polymorphism in 5HT2A and schizophrenia plus identification of new polymorphisms in the promoter

1998 • 254 citations

Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene

1996 • 246 citations

Association of polymorphism of serotonin 2A receptor gene with suicidal ideation in major depressive disorder

2000 • 229 citations

Platelet serotonin-2 receptor binding sites in depression and suicide

1990 • 223 citations

Association Between the Tryptophan Hydroxylase Gene and Manic-depressive Illness

1998 • 206 citations

Meta-analysis of association between the 5-HT2a receptor T102C polymorphism and schizophrenia

1997 • 204 citations

Serotonin transporter gene polymorphisms, alcoholism, and suicidal behavior

2000 • 202 citations

Systematic screening for mutations in the human serotonin-2A (5-HT2A) receptor gene: Identification of two naturally occurring receptor variants and association analysis in schizophrenia

1996 • 193 citations

Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients

1997 • 179 citations

Possible association of the short allele of the serotonin transporter promoter gene polymorphism (5-HTTLPR) with violent suicide

2000 • 173 citations

Frequency of long allele in serotonin transporter gene is increased in depressed suicide victims

1999 • 164 citations

Possible association between serotonin transporter gene polymorphism and violent suicidal behavior in mood disorders

2000 • 157 citations

Positive association between a DNA sequence variant in the serotonin 2A receptor gene and schizophrenia

1996 • 148 citations

Serotonergic markers in platelets of patients with major depression: upregulation of 5-HT2 receptors.

1995 • 117 citations

Platelet serotonergic indices in major depression: up-regulation of 5-HT2A receptors unchanged by antidepressant treatment

1997 • 108 citations

Analysis of catechol-O-methyltransferase and 5-hydroxytryptamine transporter polymorphisms in patients at risk for suicide

2000 • 107 citations

Serotonin2A receptor gene polymorphism in mood disorders

1997 • 106 citations

Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3→p14 by in situ hybridization

1991 • 103 citations

No Evidence for an Association of Polymorphisms of the Tryptophan Hydroxylase Gene With Affective Disorders or Attempted Suicide Among Japanese Patients

1999 • 97 citations

Search for association between suicide attempt and serotonergic polymorphisms

2000 • 97 citations

Effects of selective serotonin reuptake inhibitors on platelet serotonin parameters in major depressive disorder

1997 • 96 citations

Identification of four variants in the tryptophan hydroxylase promoter and association to behavior

1999 • 93 citations

No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder.

1998 • 85 citations

Genetics of suicide in depression.

1999 • 84 citations

TPH and suicidal behavior: a study in suicide completers

2000 • 84 citations

Suicidal Behaviors and the Tryptophan Hydroxylase Gene

1995 • 83 citations

Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism.

1992 • 78 citations

Tryptophan hydroxylase gene polymorphism (A218C) and suicidal behaviors

1999 • 76 citations

Tryptophan hydroxylase polymorphisms in suicide victims

2000 • 72 citations

3H-imipramine binding in the frontal cortex of suicides

1989 • 70 citations

The Human Tryptophan Hydroxylase Gene

1995 • 69 citations

No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder

1998 • 69 citations

Serotonin transporter gene and manic depressive illness: An association study

1997 • 65 citations

Assessment of binding indices and physiological responsiveness of the 5-HT2 receptor on human platelets

1987 • 60 citations

SEROTONIN IS REDUCED IN THE FRONTAL CORTEX OF SARDINIAN ETHANOL-PREFERRING RATS

1998 • 39 citations

Identification and analysis of new sequence variants in the human tryptophan hydroxylase (TpH) gene

2000 • 38 citations

Tryptophan hydroxylase gene 218A/C polymorphism is not associated with depressed suicide

2000 • 37 citations

Suicide on the paternal and maternal sides of depressed patients with a lifetime history of attempted suicide

1991 • 31 citations

Assignment of human tryptophan hydroxylase locus to chromosome 11: Gene duplication and translocation in evolution of aromatic amino acid hydroxylases

1987 • 28 citations

The 5′ region of the tryptophan hydroxylase gene: mutation search and association study with alcoholism

1999 • 26 citations

Assocation between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2A receptor gene

1996 • 20 citations

TRYPTOPHAN METABOLISM IN MALE SARDINIAN ALCOHOL-PREFERRING (sP) AND -NON-PREFERRING (sNP) RATS

1998 • 15 citations