Identification and analysis of new sequence variants in the human tryptophan hydroxylase (TpH) gene

Structure and function of the brain serotonin system

1992 • 2,507 citations

Allelic Variation of Human Serotonin Transporter Gene Expression

1996 • 2,225 citations

Diagnostic Interview for Genetic Studies

1994 • 2,004 citations

The mutational spectrum of single base-pair substitutions in mRNA splice junctions of human genes: Causes and consequences

1992 • 1,338 citations

Handbook of Human Genetic Linkage.

1996 • 878 citations

Handbook of human genetic linkage

1995 • 591 citations

Polymorphism in serotonin transporter gene associated with susceptibility to major depression

1996 • 534 citations

Suicidality and 5-Hydroxyindoleacetic Acid Concentration Associated With a Tryptophan Hydroxylase Polymorphism

1994 • 378 citations

‘Cold SSCP’: a simple, rapid and non-radioactive method for optimized single-strand conformation polymorphism analyses

1993 • 335 citations

A Tryptophan Hydroxylase Gene Marker for Suicidality and Alcoholism

1998 • 305 citations

Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene

1999 • 283 citations

Cerebrospinal Fluid Monoamine Metabolites and Suicidal Behavior in Depressed Patients

1989 • 281 citations

Initial splice-site recognition and pairing during pre-mRNA splicing

1996 • 281 citations

Human monoamine oxidase A gene determines levels of enzyme activity.

1991 • 259 citations

Further studies on tryptophan hydroxylase in rat brainstem and beef pineal

1969 • 225 citations

Identification, Expression, and Pharmacology of a Cys23-Ser23 Substitution in the Human 5-HT2C Receptor Gene (HTR2C)

1995 • 223 citations

Association Between the Tryptophan Hydroxylase Gene and Manic-depressive Illness

1998 • 206 citations

Tryptophan hydroxylation in brain

1964 • 195 citations

Early-Onset Alcoholics Have Lower Cerebrospinal Fluid 5-Hydroxyindoleacetic Acid Levels Than Late-Onset Alcoholics

1996 • 192 citations

Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients

1997 • 179 citations

Acting out hostility in normal volunteers: Negative correlation with levels of 5HIAA in cerebrospinal fluid

1988 • 167 citations

Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7

1997 • 166 citations

Tryptophan hydroxylase genotype is associated with impulsive-aggression measures: a preliminary study

1998 • 140 citations

Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3→p14 by in situ hybridization

1991 • 103 citations

Depression vulnerability and 5-hydroxytryptophan prophylaxis

1980 • 95 citations

No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive–compulsive disorder, anorexia nervosa, and alcoholism

1999 • 89 citations

Two naturally occurring amino acid substitutions of the 5-HT2A receptor: Similar prevalence in patients with seasonal affective disorder and controls

1996 • 86 citations

No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder.

1998 • 85 citations

Complete coding sequence of human tryptophan hydroxylase

1990 • 78 citations

Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism.

1992 • 78 citations

Characterization of the Human Tryptophan Hydroxylase Gene Promoter

1995 • 77 citations

No association of the tryptophan hydroxylase gene with bipolar affective disorder, unipolar affective disorder, or suicidal behaviour in major affective disorder

1998 • 69 citations

Nonradioactive assay for new microsatellite polymorphisms at the 5' end of the dystrophin gene, and estimation of intragenic recombination.

1991 • 61 citations

2 Naturally Occurring Amino Acid Substitutions in the Human 5-HT1A Receptor: Glycine 22 to Serine 22 and Isoleucine 28 to Valine 28

1995 • 51 citations

Highly polymorphic (GT)n repeat sequence in intron II of the human MAOB gene

1992 • 49 citations

Alternative Splicing at the 3′‐cDNA of Human Tryptophan Hydroxylase

1998 • 20 citations

CBF/NF-Y activates transcription of the human tryptophan hydroxylase gene through an inverted CCAAT box

1998 • 9 citations

Lack of association of promoter region variation in tryptophan hydrolase and serotonin transporter with obsessive compulsive disorder and eating disorders

1997 • 4 citations