Neurotrophins as in vitro growth cone guidance molecules for embryonic sensory neurons

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

The trk proto-oncogene encodes a receptor for nerve growth factor

1991 • 1,396 citations

The Trk family of neurotrophin receptors

1994 • 1,271 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3

1991 • 1,078 citations

Intracellular Signaling Pathways Activated by Neuropathic Factors

1996 • 958 citations

Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo

1951 • 947 citations

The trkB tyrosine protein kinase is a receptor for brain-derived neurotrophic factor and neurotrophin-3

1991 • 940 citations

Multiple promoters direct tissue-specific expression of the rat BDNF gene

1993 • 851 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

Binding of brain-derived neurotrophic factor to the nerve growth factor receptor

1990 • 702 citations

Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

1990 • 700 citations

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

1992 • 633 citations

trkB, a novel tyrosine protein kinase receptor expressed during mouse neural development.

1989 • 604 citations

Expression and coexpression of Trk receptors in subpopulations of adult primary sensory neurons projecting to identified peripheral targets

1994 • 581 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

Primary structure and biological activity of a novel human neurotrophic factor

1990 • 553 citations

Inhibitors of Neurite Growth

1993 • 545 citations

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

1993 • 525 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons

1992 • 521 citations

Neurotrophin signal transduction by the Trk receptor

1994 • 511 citations

Cells Expressing mRNA for Neurotrophins and their Receptors During Embryonic Rat Development

1992 • 499 citations

Characterization of the turning response of dorsal root neurites toward nerve growth factor.

1980 • 487 citations

Complementary roles of BDNF and NT-3 in vestibular and auditory development

1995 • 465 citations

Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neurotrophic factor.

1992 • 458 citations

Neurotrophin-6 is a new member of the nerve growth factor family

1994 • 404 citations

Molecular cloning of a human gene that is a member of the nerve growth factor family.

1990 • 397 citations

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

1995 • 381 citations

Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons

1993 • 338 citations

The kinetics of chemotactic peptide-induced change in F-actin content, F-actin distribution, and the shape of neutrophils.

1985 • 319 citations

Control of actin polymerization in live and permeabilized fibroblasts.

1991 • 289 citations

Developmental Neurobiology and the Natural History of Nerve Growth Factor

1982 • 289 citations

Chemotactic response of nerve fiber elongation to nerve growth factor

1978 • 279 citations

Navigational errors made by growth cones without filopodia in the embryonic xenopus brain

1993 • 264 citations

The organization of F-actin and microtubules in growth cones exposed to a brain-derived collapsing factor.

1993 • 262 citations

A sensory role for neuronal growth cone filopodia

1993 • 223 citations

Cloning and expression of a cDNA encoding a novel human neurotrophic factor

1990 • 199 citations

Axon guidance molecules

1995 • 193 citations

Fast actions of neurotrophic factors

1996 • 177 citations

Sympathetic nerve fibers ingrowth in the central nervous system of neonatal rodent upon intracerebral NGF injections.

1978 • 173 citations

Correlated Measurements of DNA, RNA, and Protein in Individual Cells by Flow Cytometry

1985 • 153 citations

Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs

1988 • 145 citations

Binding characteristics of brain-derived neurotrophic factor to its receptors on neurons from the chick embryo

1988 • 142 citations

Target attraction: Are developing axons guided by chemotropism?

1991 • 142 citations

NGF and the local control of nerve terminal growth

1994 • 140 citations

Neurotrophins Cause a New Sensation

1996 • 136 citations

Functional analysis of mutant neurotrophins deficient in low-affinity binding reveals a role for p75LNGFR in NT-4 signalling.

1995 • 131 citations

Kinetic analysis of F-actin depolymerization in polymorphonuclear leukocyte lysates indicates that chemoattractant stimulation increases actin filament number without altering the filament length distribution.

1991 • 129 citations

Guidance and induction of branch formation in developing axons by target-derived diffusible factors

1995 • 127 citations

The sensory-motor role of growth cone filopodia

1995 • 124 citations

Repulsive and inhibitory signals

1995 • 90 citations

A Pharmacological Approach to the Structure of Sodium Channels in Myelinated Axons

1979 • 89 citations

Neurotrophins and their receptors in rat peripheral trigeminal system during maxillary nerve growth

1993 • 82 citations

Coexpression of trk family members and low-affinity neurotrophin receptors in rat dorsal root ganglion neurons

1995 • 80 citations

Inhibitory factors controlling growth cone motility and guidance

1994 • 65 citations

Attractive Axon Guidance Molecules

1994 • 49 citations

Hierarchical guidance cues in the developing nervous system of C. elegans

1996 • 43 citations

Modulators of neuronal migration and neurite growth

1992 • 39 citations

Cellular mechanisms of signal transduction for neurotrophins

1994 • 35 citations

mRNAS for one, two or three members of trk receptor family are expressed in single rat trigeminal ganglion neurons

1996 • 31 citations

The dance of the growth cones — where to next?

1995 • 26 citations

Pleiotropic signaling from receptor tyrosine kinases

1993 • 21 citations

Neural Development: Chemoattractants for navigating axons

1994 • 10 citations

Neurotrophins: neural antiapoptotic molecules with neurite growth-promoting properties

1995 • 8 citations

Effects of Brain-Derived Neurotrophic Factor and Neurotrophin-4 on Embryonic Rat Sensory Neurons

1995 • 6 citations