Guidance and induction of branch formation in developing axons by target-derived diffusible factors

PAUP (phylogenetic analysis using parsimony)

2008 • 4,484 citations

The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6

1994 • 1,346 citations

Calcium-binding proteins in the nervous system

1992 • 1,321 citations

Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord

1994 • 1,311 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons

1994 • 1,065 citations

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development

1994 • 1,046 citations

Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene

1994 • 978 citations

Neurotrophin-3 enhances sprouting of corticospinal tract during development and after adult spinal cord lesion

1994 • 912 citations

The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans

1990 • 909 citations

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1994 • 804 citations

A new nomenclature for the laminins

1994 • 753 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 670 citations

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3

1994 • 635 citations

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

1994 • 620 citations

Turning of nerve growth cones induced by neurotransmitters

1994 • 583 citations

The axonal glycoprotein TAG-1 is an immunoglobulin superfamily member with neurite outgrowth-promoting activity

1990 • 569 citations

La rétine des vertébrés

1892 • 559 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegans

1992 • 503 citations

UNC-5, a transmembrane protein with immunoglobulin and thrombospondin type 1 domains, guides cell and pioneer axon migrations in C. elegans

1992 • 404 citations

Earliest sensory nerve fibres are guided to peripheral targets by attractants other than nerve growth factor

1983 • 356 citations

Endogenous NGF and nerve impulses regulate the collateral sprouting of sensory axons in the skin of the adult rat

1992 • 344 citations

Axon Guidance by Gradients of a Target-Derived Component

1992 • 312 citations

Cortical axons branch to multiple subcortical targets by interstitial axon budding: Implications for target recognition and “waiting periods”

1988 • 307 citations

Pattern-induced multi-sequence alignment (PUMA) algorithm employing secondary structure-dependent gap penalties for use in comparative protein modelling

1992 • 281 citations

Target Control of Collateral Extension and Directional Axon Growth in the Mammalian Brain

1990 • 269 citations

Alternative splicing generates a secreted form of N-CAM in muscle and brain

1988 • 245 citations

Self-assembly and calcium-binding sites in laminin. A three-arm interaction model

1993 • 239 citations

Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant

1990 • 227 citations

The Role of the Floor Plate in Axon Guidance

1995 • 218 citations

Sensory nerves in adult rats regenerate and restore sensory function to the skin independently of endogenous NGF

1992 • 191 citations

Chemorepulsion of axons in the developing mammalian central nervous system

1993 • 180 citations

Sympathetic nerve fibers ingrowth in the central nervous system of neonatal rodent upon intracerebral NGF injections.

1978 • 173 citations

Directed expression of NGF to pancreatic β cells in transgenic mice leads to selective hyperinnervation of the islets

1989 • 165 citations

The axonally secreted protein axonin-1 is a potent substratum for neurite growth.

1991 • 147 citations

Target attraction: Are developing axons guided by chemotropism?

1991 • 142 citations

Control of Topographic Retinal Axon Branching by Inhibitory Membrane-Bound Molecules

1994 • 122 citations

Expression of NGF in sympathetic neurons leads to excessive axon outgrowth from ganglia but decreased terminal innervation within tissues

1993 • 106 citations

Ventral spinal cord inhibition of neurite outgrowth from embryonic rat dorsal root ganglia

1993 • 99 citations

Molecular and cellular aspects of patterning sensory neurone connections in the vertebrate nervous system

1987 • 94 citations

Action of a diffusible target-derived chemoattractant on cortical axon branch induction and directed growth

1994 • 84 citations

Growth cone behavior on gradients of substratum bound laminin

1988 • 72 citations

Cleavage of A-CAM by endogenous proteinases in cultured lens cells and in developing chick embryos

1990 • 65 citations

Axon guidance mechanisms in Caenorhabditis elegans

1994 • 44 citations

Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression

1990 • 38 citations