Target attraction: Are developing axons guided by chemotropism?

Physics of chemoreception

1977 • 1,844 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

Ability of polymorphonuclear leukocytes to orient in gradients of chemotactic factors.

1977 • 905 citations

Binding of brain-derived neurotrophic factor to the nerve growth factor receptor

1990 • 702 citations

Chemotropic guidance of developing axons in the mammalian central nervous system

1988 • 681 citations

Principles of neural development

1985 • 627 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

Chemotaxis in Eukaryotic Cells: A Focus on Leukocytes and Dictyostelium

1988 • 623 citations

Timing and site of nerve growth factor synthesis in developing skin in relation to innervation and expression of the receptor

1987 • 555 citations

Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth Factor

1979 • 522 citations

Characterization of the turning response of dorsal root neurites toward nerve growth factor.

1980 • 487 citations

Earliest sensory nerve fibres are guided to peripheral targets by attractants other than nerve growth factor

1983 • 356 citations

Cortical axons branch to multiple subcortical targets by interstitial axon budding: Implications for target recognition and “waiting periods”

1988 • 307 citations

The Structure of the Retina

1972 • 304 citations

Developmental Neurobiology and the Natural History of Nerve Growth Factor

1982 • 289 citations

Chemotactic response of nerve fiber elongation to nerve growth factor

1978 • 279 citations

Target Control of Collateral Extension and Directional Axon Growth in the Mammalian Brain

1990 • 269 citations

Chemotropic effect of specific target epithelium in the developing mammalian nervous system

1986 • 235 citations

Orientation of commissural axons in vitro in response to a floor plate-derived chemoattractant

1990 • 227 citations

Relation of target encounter and neuronal death to nerve growth factor responsiveness in the developing mouse trigeminal ganglion

1984 • 225 citations

Formation of target-specific neuronal projections in organotypic slice cultures from rat visual cortex

1990 • 202 citations

A stochastic model for leukocyte random motility and chemotaxis based on receptor binding fluctuations

1988 • 197 citations

Chemotactic peptide receptor modulation in polymorphonuclear leukocytes.

1980 • 183 citations

Sympathetic nerve fibers ingrowth in the central nervous system of neonatal rodent upon intracerebral NGF injections.

1978 • 173 citations

Principles of neural development

1985 • 160 citations

Tissue explants affecting extension and orientation of axons in cultured chick embryo ganglia*1

1977 • 158 citations

Muscle nerve branches do not develop in chick wings devoid of muscle

1981 • 153 citations

Developmental changes of nerve growth factor levels in sympathetic ganglia and their target organs

1988 • 145 citations

Local positional cues in the neuroepithelium guide retinal axons in embryonic Xenopus brain

1989 • 135 citations

Neuronal precursor cells in chick dorsal root ganglia: Differentiation and survival in vitro

1988 • 98 citations

How do retinal axons find their targets on the tectum?

1984 • 98 citations

Sensory neurite growth cone guidance by substrate adsorbed nerve growth factor

1985 • 91 citations

Distribution of laminin and fibronectin along peripheral trigeminal axon pathways in the developing chick

1987 • 83 citations

Proximal tissues and patterned neurite outgrowth at the lumbosacral level of the chick embryo: Deletion of the dermamyotome

1987 • 82 citations

Rapid retraction of neurites by sensory neurons in response to increased concentrations of nerve growth factor.

1980 • 57 citations

Axon guidance in muscleless chick wings: the role of muscle cells in motoneuronal pathway selection and muscle nerve formation

1990 • 55 citations

Myoblasts and myoblast‐conditioned medium attract the earliest spinal neurites from frog embryos.

1986 • 43 citations

Fasciculation in the early mouse trigeminal nerve is not ordered in relation to the emerging pattern of whisker follicles

1986 • 42 citations

Cutaneous nerves of the embryonic chick wing do not develop in regions denuded of ectoderm

1989 • 31 citations

A role for nerve growth factor in collateral reinnervation from sensory nerves in the guinea pig

1989 • 27 citations