Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Trophic factors and neuronal survival

1989 • 1,631 citations

Functions of the neurotrophins during nervous system development: What the knockouts are teaching us

1994 • 1,431 citations

GDNF: a Potent Survival Factor for Motoneurons Present in Peripheral Nerve and Muscle

1994 • 1,261 citations

Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo

1995 • 1,084 citations

Mice lacking brain-derived neurotrophic factor develop with sensory deficits

1994 • 1,066 citations

Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development

1994 • 1,046 citations

Neurotrophin-5: A novel neurotrophic factor that activates trk and trkB

1991 • 847 citations

Evolutionary studies of the nerve growth factor family reveal a novel member abundantly expressed in xenopus ovary

1991 • 836 citations

Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents

1994 • 804 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain

1990 • 748 citations

Developing motor neurons rescued from programmed and axotomy-induced cell death by GDNF

1995 • 686 citations

Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death

1993 • 670 citations

Mesencephalic dopaminergic neurons protected by GDNF from axotomy-induced degeneration in the adult brain

1995 • 659 citations

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3

1994 • 635 citations

Mammalian neurotrophin-4: structure, chromosomal localization, tissue distribution, and receptor specificity.

1992 • 633 citations

In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons

1995 • 593 citations

Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon

1994 • 374 citations

Different neurotrophins are expressed and act in a developmental sequence to promote the survival of embryonic sensory neurons

1993 • 338 citations

The trk B tyrosine protein kinase is a receptor for neurotrophin-4

1992 • 326 citations

Widespread and Developmentally Regulated Expression of Neurotrophin‐4 mRNA in Rat Brain and Peripheral Tissues

1993 • 256 citations

NT-3 stimulates sympathetic neuroblast proliferation by promoting precursor survival

1993 • 218 citations

Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor.

1994 • 172 citations

Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons.

1994 • 120 citations

Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons

1993 • 110 citations

Neurotrophin-4 is a target-derived neurotrophic factor for neurons of the trigeminal ganglion

1993 • 106 citations

Neurotrophic factors and their receptors

1994 • 47 citations