Molecular cloning and neurotrophic activities of a protein with structural similarities to nerve growth factor: developmental and topographical expression in the brain.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

1988 • 4,669 citations

Translational Findings on Brain-Derived Neurotrophic Factor and Anxiety: Contributions from Basic Research to Clinical Practice

2013 • 3,921 citations

The Nerve Growth Factor 35 Years Later

1987 • 3,107 citations

Purification of a new neurotrophic factor from mammalian brain.

1982 • 1,762 citations

Physiology of nerve growth factor.

1980 • 1,602 citations

Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections

1986 • 1,458 citations

Molecular cloning and expression of brain-derived neurotrophic factor

1989 • 1,453 citations

Regressive Events in Neurogenesis

1984 • 1,330 citations

Neurotrophin-3: a Neurotrophic Factor Related to NGF and BDNF

1990 • 1,261 citations

Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family

1990 • 1,140 citations

Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection.

1986 • 1,063 citations

Nerve Growth Factor Treatment After Brain Injury Prevents Neuronal Death

1987 • 942 citations

Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation.

1985 • 941 citations

Human IL-3 (multi-CSF): Identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3

1986 • 823 citations

High efficiency polyoma DNA transfection of chloroquine treated cells

1983 • 711 citations

Nerve growth factor receptors. Characterization of two distinct classes of binding sites on chick embryo sensory ganglia cells.

1979 • 627 citations

Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor

1989 • 624 citations

Studies on the expression of the beta nerve growth factor (NGF) gene in the central nervous system: level and regional distribution of NGF mRNA suggest that NGF functions as a trophic factor for several distinct populations of neurons.

1986 • 528 citations

Development and regional expression of beta nerve growth factor messenger RNA and protein in the rat central nervous system.

1986 • 525 citations

Expression of the beta-nerve growth factor gene correlates with the density of sympathetic innervation in effector organs.

1984 • 519 citations

Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells

1986 • 519 citations

Grafting Genetically Modified Cells to the Damaged Brain: Restorative Effects of NGF Expression

1988 • 508 citations

Brain-derived neurotrophic factor prevents neuronal death in vivo

1988 • 490 citations

Human β-nerve growth factor gene sequence highly homologous to that of mouse

1983 • 486 citations

Isolation and nucleotide sequence of a cDNA encoding the precursor of mouse nerve growth factor

1983 • 474 citations

Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA.

1981 • 438 citations

Cholinergic Neuronotrophic Factors: Intraocular Distribution of Trophic Activity for Ciliary Neurons

1979 • 414 citations

Placode and neural crest-derived sensory neurons are responsive at early developmental stages to brain-derived neurotrophic factor

1985 • 384 citations

Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues.

1984 • 359 citations

Expression of the β-Nerve Growth Factor Gene in Hippocampal Neurons

1988 • 356 citations

Expression of nerve growth factor receptor mRNA is developmentally regulated and increased after axotomy in rat spinal cord motoneurons

1989 • 331 citations

Rat β‐nerve growth factor sequence and site of synthesis in the adult hippocampus

1988 • 309 citations

The response of chick sensory neurons to brain-derived neurotrophic factor

1986 • 251 citations

Developmental and regional expression of β-nerve growth factor receptor mRNA in the chick and rat

1988 • 245 citations

Nerve growth factor mRNA and protein in the testis and epididymis of mouse and rat.

1988 • 200 citations

Adrenergic differentiation of cells of the cholinergic ciliary and Remak ganglia in avian embryo after in vivo transplantation.

1978 • 155 citations

Expression of β-Nerve Growth Factor Receptor mRNA in Sertoli Cells Downregulated by Testosterone

1990 • 154 citations

A cell line producing recombinant nerve growth factor evokes growth responses in intrinsic and grafted central cholinergic neurons.

1989 • 147 citations

Mouse nerve growth factor gene: structure and expression.

1987 • 136 citations

Rescue of basal forebrain cholinergic neurons after implantation of genetically modified cells producing recombinant NGF

1990 • 114 citations

Stage-dependent stimulation of neurite outgrowth exerted by nerve growth factor and chick heart in cultured embryonic ganglia

1979 • 92 citations

Structure-function studies of nerve growth factor: functional importance of highly conserved amino acid residues.

1990 • 69 citations

Trophic molecules and evolution of the nervous system.

1986 • 56 citations

Internalization and cycling of nerve growth factor in PC12 cells: Interconversion of type II (fast) and type I (slow) nerve growth factor receptors

1988 • 47 citations

The chick embryo nodose ganglion: Effects of nerve growth factor in culture

1980 • 37 citations

Production and Characterization of Biologically Active Recombinant Beta Nerve Growth Factor

1988 • 31 citations

Mouse Nerve Growth Factor Gene: Structure and Expression

1987 • 30 citations