Cdc2 Kinase Directly Phosphorylates the cis-Golgi Matrix Protein GM130 and Is Required for Golgi Fragmentation in Mitosis

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

Rapid identification of proteins by peptide-mass fingerprinting

1993 • 1,619 citations

[11] Phosphopeptide mapping and phosphoamino acid analysis by two-dimensional separation on thin-layer cellulose plates

1991 • 1,463 citations

Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5

1997 • 1,324 citations

Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

1998 • 1,003 citations

Cyclin‐dependent protein kinases: Key regulators of the eukaryotic cell cycle

1995 • 918 citations

Characterization of a cis-Golgi matrix protein, GM130.

1995 • 797 citations

Use of an oriented peptide library to determine the optimal substrates of protein kinases

1994 • 645 citations

GRASP65, a Protein Involved in the Stacking of Golgi Cisternae

1997 • 415 citations

The Vesicle Docking Protein p115 Binds GM130, a cis-Golgi Matrix Protein, in a Mitotically Regulated Manner

1997 • 408 citations

Initial docking of ER-derived vesicles requires Uso1p and Ypt1p but is independent of SNARE proteins

1998 • 370 citations

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

1997 • 311 citations

Three-dimensional electron microscopy: structure of the Golgi apparatus.

1990 • 307 citations

A Role for Giantin in Docking COPI Vesicles to Golgi Membranes

1998 • 284 citations

Activation of the Protein Kinase p38 in the Spindle Assembly Checkpoint and Mitotic Arrest

1998 • 264 citations

A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack.

1992 • 233 citations

Partitioning of the Golgi Apparatus during Mitosis in Living HeLa Cells

1997 • 219 citations

Cdk2 Kinase Is Required for Entry into Mitosis as a Positive Regulator of Cdc2–Cyclin B Kinase Activity

1996 • 214 citations

TRANSPORT VESICLE DOCKING: SNAREs and Associates

1996 • 207 citations

Assembly of the ER to Golgi SNARE complex requires Uso1p.

1996 • 203 citations

A Predictive Scale for Evaluating Cyclin-dependent Kinase Substrates

1996 • 201 citations

p115 is a general vesicular transport factor related to the yeast endoplasmic reticulum to Golgi transport factor Uso1p.

1995 • 199 citations

Signaling via Mitogen-Activated Protein Kinase Kinase (MEK1) Is Required for Golgi Fragmentation during Mitosis

1998 • 186 citations

COP-coated vesicles are involved in the mitotic fragmentation of Golgi stacks in a cell-free system.

1994 • 122 citations

Transcytosis-associated protein (TAP)/p115 is a general fusion factor required for binding of vesicles to acceptor membranes.

1995 • 114 citations

Cell Cycle Regulation of p70 S6 Kinase and p42/p44 Mitogen-activated Protein Kinases in Swiss Mouse 3T3 Fibroblasts

1996 • 103 citations

Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation.

1994 • 97 citations

Mitotic disassembly of the Golgi apparatus in vivo

1995 • 93 citations

Binding of the Vesicle Docking Protein p115 to Golgi Membranes Is Inhibited under Mitotic Conditions

1996 • 67 citations

A role for tubular networks and a COP I-independent pathway in the mitotic fragmentation of Golgi stacks in a cell-free system.

1995 • 60 citations

THREE-DIMENSIONAL ELECTRON MICROSCOPY

1981 • 57 citations

Inhibition of intra-Golgi transport in vitro by mitotic kinase.

1993 • 49 citations

Phosphorylation of the Vesicle Docking Protein p115 Regulates Its Association with the Golgi Membrane

1998 • 46 citations

A 40‐kDa myelin basic protein kinase, distinct from erk1 and erk2, is activated in mitotic HeLa cells

1994 • 42 citations

Cyclin A‐mediated inhibition of intra‐Golgi transport requires p34^cdc2

1993 • 13 citations