Aging Reduces Proliferative Capacities of Liver by Switching Pathways of C/EBPα Growth Arrest

The Liver: Biology and Pathobiology.

1983 • 1,628 citations

Liver regeneration

2000 • 987 citations

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 • 922 citations

Predictors of morbidity and mortality after the first episode of upper gastrointestinal bleeding in liver cirrhosis

2000 • 892 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

Tissue-specific expression, developmental regulation, and genetic mapping of the gene encoding CCAAT/enhancer binding protein.

1989 • 641 citations

The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest

1994 • 625 citations

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

1996 • 446 citations

Altered control of cellular proliferation in the absence of mammalian brahma (SNF2α)

1998 • 421 citations

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein.

1996 • 393 citations

Transcriptional control of liver regeneration

1996 • 353 citations

C/EBPα Arrests Cell Proliferation through Direct Inhibition of Cdk2 and Cdk4

2001 • 344 citations

E2F Repression by C/EBPα Is Required for Adipogenesis and Granulopoiesis In Vivo

2001 • 321 citations

Reciprocal Regulation of Adipogenesis by Myc and C/EBPα

1992 • 296 citations

c-Myc Is a Critical Target for C/EBPα in Granulopoiesis

2001 • 260 citations

Functional Interactions between the hBRM/hBRG1 Transcriptional Activators and the pRB Family of Proteins

1996 • 252 citations

THE INFLUENCE OF AGE UPON THE INCORPORATION OF THYMIDINE-2-C14 INTO THE DNA OF REGENERATING RAT LIVER.

1964 • 240 citations

CCAAT/Enhancer Binding Protein α Regulates p21 Protein and Hepatocyte Proliferation in Newborn Mice

1997 • 236 citations

Target Gene Specificity of E2F and Pocket Protein Family Members in Living Cells

2000 • 230 citations

Cooperation between C/EBPα TBP/TFIIB and SWI/SNF recruiting domains is required for adipocyte differentiation

2001 • 197 citations

Distinct Stages in Adipogenesis Revealed by Retinoid Inhibition of Differentiation after Induction of PPARγ

1996 • 181 citations

C/EBPα Inhibits Cell Growth via Direct Repression of E2F-DP-Mediated Transcription

2000 • 172 citations

The identification of E2F1-specific target genes

2002 • 148 citations

C/EBPα Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice

1999 • 108 citations

CCAAT/Enhancer-binding Proteins

1999 • 91 citations

Delayed and reduced cell replication and diminishing levels of DNA polymerase‐α in regenerating liver of aging mice

1984 • 85 citations

C/EBPalpha triggers proteasome-dependent degradation of cdk4 during growth arrest

2002 • 84 citations

Regenerating livers of old rats contain high levels of C/EBPalpha that correlate with altered expression of cell cycle associated proteins

1998 • 68 citations

c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity.

2000 • 67 citations

E2F/p107 and E2F/p130 complexes are regulated by C/EBP in 3T3-L1 adipocytes

1999 • 55 citations

Cell Cycle — Materials and Methods

1996 • 53 citations

Cell Cycle-Regulated Transcription Factors; Bandshift Assays

1996 • 1 citations