Delayed and reduced cell replication and diminishing levels of DNA polymerase‐α in regenerating liver of aging mice

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

The limited in vitro lifetime of human diploid cell strains

1965 • 5,595 citations

Ciba Foundation Symposium

1957 • 1,100 citations

Replicative life-span of cultivated human cells. Effects of donor's age, tissue, and genotype.

1970 • 1,002 citations

Multienzyme complex for metabolic channeling in mammalian DNA replication.

1980 • 349 citations

The in vivo life span of normal and preneoplastic mouse mammary glands: a serial transplantation study.

1968 • 276 citations

Regeneration of Rat Liver: Transfer of Humoral Agent by Cross Circulation

1967 • 275 citations

Purification and Properties of Deoxyribonucleic Acid Polymerase from Nuclei of Sea Urchin Embryos

1969 • 248 citations

Loss of proliferative capacity in immunohemopoietic stem cells caused by serial transplantation rather than aging.

1978 • 224 citations

Immunologic deficiencies in senescence. I. Characterization of intrinsic deficiencies.

1972 • 177 citations

The Infidelity of Avian Myeloblastosis Virus Deoxyribonucleic Acid Polymerase in Polynucleotide Replication

1974 • 172 citations

THE FATE OF SERIALLY TRANSPLANTED BONE MARROW CELL POPULATIONS FROM YOUNG AND OLD DONORS

1976 • 145 citations

Review Lectures on Senescence - II. Heterochronic transplantation in the study of ageing

1962 • 127 citations

Normal Production of Erythrocytes by Mouse Marrow Continuous for 73 Months

1973 • 120 citations

CIBA FOUNDATION SYMPOSIA

1962 • 119 citations

Enzymes of Nucleic Acid Synthesis and Modification

2018 • 116 citations

The influence of host and tissue age on life span and growth rate of serially transplanted mouse mammary gland

1971 • 116 citations

The effect of age on regeneration of rat liver.

1950 • 108 citations

Nuclear deoxyribonucleic acid polymerases of liver.

1975 • 107 citations

Cellular aging--clonal senescence. A review (Part I).

1977 • 105 citations

The limited growth span of cell strains isolated from the chick embryo

1967 • 105 citations

The use of frequency distributions of cell diameters to characterize cell populations in tissue culture

1967 • 103 citations

The biology of human aging

1973 • 95 citations

Decline in the growth potential of spleen-colonizing bone marrow stem cells of long-lived aging mice.

1976 • 94 citations

Lymphopoietic Potential of Bone Marrow Cells from Aged Mice: Comparison of the Cellular Constituents of Bone Marrow from Young and Aged Mice

1974 • 84 citations

Age-dependent regulation of mammalian DNA synthesis and cell proliferation In vivo

1972 • 67 citations

Transplantability and Life Span of Mammary Gland during Serial Transplantation in Mice

1967 • 61 citations

Nuclear location of mammalian DNA polymerase activities

1976 • 56 citations

Intracellular localization of mouse DNA polymerase-alpha.

1976 • 53 citations

Immunologic Deficiencies in Senescence

1972 • 49 citations

Changes in DNA polymerases .alpha., .beta., and .gamma. during the replicative life span of cultured human fibroblasts

1982 • 48 citations

Stem Cell Lines from Old Immunodeficient Donors Give Normal Responses in Young Recipients

1977 • 46 citations

Sea urchin nuclear DNA polymerase

1972 • 40 citations

Intracellular localization of DNA polymerase activities within large oocytes of the frog, Xenopus laevis

1980 • 39 citations

Intracellular migration of DNA polymerase in early developing sea urchin embryos

1970 • 35 citations

Study of DNA synthesis in chromatin isolated from HeLa cells

1977 • 35 citations

Evidence that a critical threshold of DNA polymerase‐alpha activity may be required for the initiation of DNA synthesis in mammalian cell heterokaryons

1982 • 33 citations

On the activity and fidelity of chromatin‐associated hepatic DNA polymerase‐β in aging murine species of different life spans

1981 • 31 citations

Intracellular localization of DNA polymerase alpha.

1981 • 26 citations

Liver regeneration and the "critical mass" hypothesis.

1969 • 23 citations

The effect of aging on rat liver regeneration

1982 • 18 citations

Replicative activity of isolated chromatin from proliferating and quiescent early passage and aging cultured mouse cells

1979 • 15 citations

DNA Polymerases of Anucleated Cells

1979 • 13 citations

Depletion of reserve in the hemopoietic system: I. Self-replication by stromal cells related to chronologic age

1982 • 10 citations

Reticulocyte DNA polymerase

1974 • 9 citations

Persistent cytoplasmic location of a DNA polymerase β in sea urchins during development

1980 • 6 citations