E2F/p107 and E2F/p130 complexes are regulated by C/EBP in 3T3-L1 adipocytes

The retinoblastoma protein and cell cycle control

1995 • 4,873 citations

The regulation of E2F by pRB-family proteins

1998 • 2,297 citations

Tumor Suppressor Genes

1991 • 1,784 citations

A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.

1990 • 1,517 citations

Retinoblastoma protein recruits histone deacetylase to repress transcription

1998 • 1,231 citations

Isolation of a recombinant copy of the gene encoding C/EBP.

1988 • 1,003 citations

Impaired Energy Homeostasis in C/EBPα Knockout Mice

1995 • 925 citations

Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins.

1995 • 922 citations

Retinoblastoma protein represses transcription by recruiting a histone deacetylase

1998 • 919 citations

Cellular Targets for Activation by the E2F1 Transcription Factor Include DNA Synthesis- and G₁/S-Regulatory Genes

1995 • 910 citations

Biological Role of the CCAAT/Enhancer-binding Protein Family of Transcription Factors

1998 • 799 citations

CCAAT-Enhancer Binding Protein: A Component of a Differentiation Switch

1991 • 733 citations

The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F.

1992 • 587 citations

Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interaction.

1993 • 530 citations

Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression.

1994 • 493 citations

CCAAT/enhancer binding protein activates the promoter of the serum albumin gene in cultured hepatoma cells.

1989 • 488 citations

Ectopic expression of the CCAAT/enhancer-binding protein alpha promotes the adipogenic program in a variety of mouse fibroblastic cells.

1994 • 450 citations

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs.

1996 • 446 citations

Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2

1997 • 438 citations

CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein.

1996 • 393 citations

E2F3 activity is regulated during the cell cycle and is required for the induction of S phase

1998 • 382 citations

Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A

1991 • 374 citations

A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex

1992 • 361 citations

Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint

1995 • 361 citations

Targeted disruption of p107: functional overlap between p107 and Rb.

1996 • 333 citations

Ubiquitination of p53 and p21 Is Differentially Affected by Ionizing and UV Radiation

1997 • 316 citations

Increased Hepatic Cell Proliferation and Lung Abnormalities in Mice Deficient in CCAAT/Enhancer Binding Protein α

1996 • 289 citations

Peroxisome Proliferator Activated Receptor γ, CCAAT/ Enhancer-binding Protein α, and Cell Cycle Status Regulate the Commitment to Adipocyte Differentiation

1997 • 272 citations

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation.

1996 • 251 citations

Transcription of the E2F-1 Gene Is Rendered Cell Cycle Dependent by E2F DNA-Binding Sites within Its Promoter

1995 • 250 citations

CCAAT/Enhancer Binding Protein α Regulates p21 Protein and Hepatocyte Proliferation in Newborn Mice

1997 • 236 citations

The Accumulation of an E2F-p130 Transcriptional Repressor Distinguishes a G₀ Cell State From a G₁ Cell State

1996 • 222 citations

E2F-6, a member of the E2F family that can behave as a transcriptional repressor

1998 • 217 citations

Strain-dependent embryonic lethality in mice lacking the retinoblastoma-related p130 gene

1998 • 181 citations

Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6

1998 • 179 citations

Strain-Dependent Myeloid Hyperplasia, Growth Deficiency, and Accelerated Cell Cycle in Mice Lacking the Rb-Related p107 Gene

1998 • 142 citations

Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter.

1994 • 141 citations

Regulation and Expression of Retinoblastoma Proteins p107 and p130 during 3T3-L1 Adipocyte Differentiation

1997 • 136 citations

Inhibition of cell proliferation by C/EBPα occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen

1995 • 133 citations

Role of the CCAAT/Enhancer Binding Protein-α Transcription Factor in the Glucocorticoid Stimulation of p21 Gene Promoter Activity in Growth-arrested Rat Hepatoma Cells

1998 • 122 citations

C/EBPα Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice

1999 • 108 citations

Essential Role of E2F Recognition Sites in Regulation of the Proliferating Cell Nuclear Antigen Gene Promoter during Drosophila Development

1995 • 82 citations

Regenerating livers of old rats contain high levels of C/EBPalpha that correlate with altered expression of cell cycle associated proteins

1998 • 68 citations

Adenovirus-mediated Transfer of CCAAT/Enhancer-binding Protein-α Identifies a Dominant Antiproliferative Role for This Isoform in Hepatocytes

1996 • 51 citations

Lack of C/EBP? gene expression results in increased DNA synthesis and an increased frequency of immortalization of freshly isolated mice hepatocytes

1998 • 45 citations