Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
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References (37)
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
2001 • 9,275 citations
Seven-transmembrane receptors
2002 • 2,571 citations
International union of pharmacology. XXIII. The angiotensin II receptors.
2000 • 2,055 citations
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 • 1,427 citations
G PROTEIN–COUPLED RECEPTOR KINASES
1998 • 1,335 citations
β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor
1996 • 1,329 citations
THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN–COUPLED RECEPTOR REGULATION
1998 • 1,074 citations
G Protein-coupled Receptors
1998 • 1,033 citations
Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors
2000 • 835 citations
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 • 808 citations
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 • 804 citations
β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2
2000 • 799 citations
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 • 655 citations
Beta-adrenergic receptor kinase: identification of a novel protein kinase that phosphorylates the agonist-occupied form of the receptor.
1986 • 650 citations
The β 2 -adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis
1999 • 615 citations
Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.
1992 • 531 citations
Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and ß-arrestin proteins
2002 • 519 citations
Desensitization of G-protein-coupled Receptors
1999 • 510 citations
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 • 487 citations
Regulation of G Protein-Coupled Receptor Kinases and Arrestins During Receptor Desensitization
2003 • 440 citations
Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
2003 • 397 citations
The proliferative and antiapoptotic effects of substance P are facilitated by formation of a β-arrestin-dependent scaffolding complex
2000 • 392 citations
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 • 323 citations
Phosphorylation of the Type 1A Angiotensin II Receptor by G Protein-coupled Receptor Kinases and Protein Kinase C
1996 • 246 citations
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 • 232 citations
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 • 222 citations
Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
1999 • 188 citations
Differential Effects of CC Chemokines on CC Chemokine Receptor 5 (CCR5) Phosphorylation and Identification of Phosphorylation Sites on the CCR5 Carboxyl Terminus
1999 • 186 citations
Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2
2004 • 170 citations
Phosphorylation and desensitization of human m2 muscarinic cholinergic receptors by two isoforms of the beta-adrenergic receptor kinase
1993 • 96 citations
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.
1996 • 95 citations
Phosphorylation of β-Arrestin2 Regulates Its Function in Internalization of β2-Adrenergic Receptors
2002 • 93 citations
The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization.
1996 • 84 citations
Bimodal Regulation of the Human H1 Histamine Receptor by G Protein-coupled Receptor Kinase 2
2004 • 80 citations
Regulation of Arrestin-3 Phosphorylation by Casein Kinase II
2002 • 59 citations
Specificity of G Protein-Coupled Receptor Kinase 6-Mediated Phosphorylation and Regulation of Single-Cell M3Muscarinic Acetylcholine Receptor Signaling
2003 • 40 citations
Identification of protein kinase C phosphorylation sites in the angiotensin II (AT1A) receptor
1999 • 37 citations