Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2

β-Arrestin-Dependent Formation of β ₂ Adrenergic Receptor-Src Protein Kinase Complexes

1999 • 1,427 citations

G PROTEIN–COUPLED RECEPTOR KINASES

1998 • 1,335 citations

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function

1990 • 1,162 citations

THE ROLE OF RECEPTOR KINASES AND ARRESTINS IN G PROTEIN–COUPLED RECEPTOR REGULATION

1998 • 1,074 citations

G Protein-coupled Receptors

1998 • 1,033 citations

Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors

2000 • 835 citations

Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds

2001 • 808 citations

β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

2000 • 804 citations

β-Arrestin–Dependent Endocytosis of Proteinase-Activated Receptor 2 Is Required for Intracellular Targeting of Activated Erk1/2

2000 • 799 citations

Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2

2003 • 655 citations

The β ₂ -adrenergic receptor/βarrestin complex recruits the clathrin adaptor AP-2 during endocytosis

1999 • 615 citations

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

1992 • 531 citations

The proliferative and antiapoptotic effects of substance P are facilitated by formation of a β-arrestin-dependent scaffolding complex

2000 • 392 citations

β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation

2002 • 386 citations

β-Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation

2002 • 359 citations

beta -Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking

2001 • 346 citations

The Stability of the G Protein-coupled Receptor-β-Arrestin Interaction Determines the Mechanism and Functional Consequence of ERK Activation

2003 • 346 citations

Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

2003 • 316 citations

ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling

2003 • 241 citations

Side-Chain Substitutions within Angiotensin II Reveal Different Requirements for Signaling, Internalization, and Phosphorylation of Type 1A Angiotensin Receptors

2002 • 235 citations

Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1

2000 • 235 citations

Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference

2003 • 232 citations

A β-Arrestin-dependent Scaffold Is Associated with Prolonged MAPK Activation in Pseudopodia during Protease-activated Receptor-2-induced Chemotaxis

2003 • 199 citations

Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.

1992 • 157 citations

Identification of NSF as a β-Arrestin1-binding Protein

1999 • 139 citations

Agonist-Stimulated and Tonic Internalization of Metabotropic Glutamate Receptor 1a in Human Embryonic Kidney 293 Cells: Agonist-Stimulated Endocytosis Is β-Arrestin1 Isoform-Specific

2001 • 115 citations

The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization.

1996 • 84 citations

Induction of experimental autoimmune uveitis by the retinal photoreceptor cell protein, phosducin

1992 • 58 citations

β‐Arrestin 1 Couples Thrombin to the Rapid Activation of the Akt Pathway

2002 • 21 citations