Inhibition of AP-1 by the Glucocorticoid-inducible Protein GILZ

TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function

1997 • 2,571 citations

Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

1995 • 2,390 citations

A CBP Integrator Complex Mediates Transcriptional Activation and AP-1 Inhibition by Nuclear Receptors

1996 • 2,183 citations

Steroid hormone receptors: Many Actors in search of a plot

1995 • 1,854 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Nuclear Receptor Coactivator ACTR Is a Novel Histone Acetyltransferase and Forms a Multimeric Activation Complex with P/CAF and CBP/p300

1997 • 1,472 citations

Transcription Factor Interactions: Selectors of Positive or Negative Regulation from a Single DNA Element

1990 • 1,326 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

DNA Binding of the Glucocorticoid Receptor Is Not Essential for Survival

1998 • 1,081 citations

Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.

1994 • 1,057 citations

Glucocorticoids in T Cell Development and Function

2000 • 783 citations

Glucocorticoid Therapy for Immune-Mediated Diseases: Basic and Clinical Correlates

1993 • 762 citations

DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo

1983 • 692 citations

Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ

1995 • 692 citations

Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

1985 • 589 citations

Glucocorticoid-induced inhibition of T cell growth factor production. I. The effect on mitogen-induced lymphocyte proliferation.

1979 • 567 citations

A distinct modulating domain in glucocorticoid receptor monomers in the repression of activity of the transcription factor AP-1.

1994 • 527 citations

Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA

1998 • 510 citations

Negative Regulation by Glucocorticoids Through Interference with a cAMP Responsive Enhancer

1988 • 502 citations

Hormone-mediated repression: a negative glucocorticoid response element from the bovine prolactin gene.

1988 • 485 citations

A New Dexamethasone-Induced Gene of the Leucine Zipper Family Protects T Lymphocytes from TCR/CD3-Activated Cell Death

1997 • 447 citations

Transcriptional cross-talk, the second mode of steroid hormone receptor action

1998 • 390 citations

The histone acetylase PCAF is a nuclear receptor coactivator

1998 • 389 citations

Glucocorticoid-mediated repression of nuclear factor-κBdependent transcription involves direct interference with transactivation

1997 • 371 citations

Glucocorticoid-Induced Inhibition of T Cell Growth Factor Production

1979 • 364 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Deficiency of PTEN in Jurkat T Cells Causes Constitutive Localization of Itk to the Plasma Membrane and Hyperresponsiveness to CD3 Stimulation

2000 • 345 citations

New Twists in Gene Regulation by Glucocorticoid Receptor: Is DNA Binding Dispensable?

1998 • 330 citations

Transactivation by AP-1 Is a Molecular Target of T Cell Clonal Anergy

1992 • 322 citations

Nuclear receptors: coactivators, corepressors and chromatin remodeling in the control of transcription

1999 • 318 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Interference between pathway-specific transcription factors: glucocorticoids antagonize phorbol ester-induced AP-1 activity without altering AP-1 site occupation in vivo.

1992 • 282 citations

Glucocorticoid Receptor Binding to a Specific DNA Sequence Is Required for Hormone-Dependent Repression of Pro-Opiomelanocortin Gene Transcription

1989 • 265 citations

The fine specificity of antigen and la determinant recognition by T cell hybridoma clones specific for pigeon cytochrome c

1982 • 244 citations

Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids.

1995 • 230 citations

Two NFAT Transcription Factor Binding Sites Participate in the Regulation of CD95 (Fas) Ligand Expression in Activated Human T Cells

1997 • 222 citations

How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis

2000 • 212 citations

The role of NF-AT transcription factors in T cell activation and differentiation11We dedicate this review to Prof. Dr. Rigomar Rieger (Gatersleben), a great scientist and man, on the occasion of his 70th birthday. One of us (E.S.) had the pleasure of working in his department.

2000 • 203 citations

Sequential Involvement of NFAT and Egr Transcription Factors in FasL Regulation

2000 • 167 citations

Negative regulation of interleukin 2 transcription by the glucocorticoid receptor.

1992 • 164 citations

Cyclosporin A-Sensitive Transcription Factor Egr-3 Regulates Fas Ligand Expression

1998 • 164 citations

Transcriptional Regulation of the Human FasL Promoter-Enhancer Region

1998 • 156 citations

Co-localization of elements required for phorbol ester stimulation and glucocorticoid repression of proliferin gene expression.

1989 • 154 citations

Identification of two NF-kappa B sites in mouse CD95 ligand (Fas ligand) promoter: functional analysis in T cell hybridoma.

1998 • 150 citations

Identification of Two NF-κB Sites in Mouse CD95 Ligand (Fas Ligand) Promoter: Functional Analysis in T Cell Hybridoma

1998 • 124 citations

Interference of pathway specific transcription factors

1992 • 120 citations

Fatal interactions: fas-induced apoptosis of mature T cells

1994 • 118 citations

Transforming Growth Factor-β-stimulated Clone-22 Is a Member of a Family of Leucine Zipper Proteins That Can Homo- and Heterodimerize and Has Transcriptional Repressor Activity

1999 • 110 citations

Functional Interference between the Ubiquitous and Constitutive Octamer Transcription Factor 1 (OTF-1) and the Glucocorticoid Receptor by Direct Protein-Protein Interaction Involving the Homeo Subdomain of OTF-1

1992 • 97 citations

A Negative Regulatory Region Containing a Glucocorticosteroid Response Element (nGRE) in the Human Interleukin-1β Gene

1997 • 82 citations

Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.

1994 • 81 citations

Rapid turnover of the CD3ζ chain independent of the TCR-CD3 complex in normal T cells

1995 • 78 citations

Transcriptional regulation of the interleukin 2 gene by glucocorticoid hormones. Role of steroid receptor and antigen-responsive 5'-flanking sequences.

1990 • 77 citations

Ligand-specific transactivation of gene expression by a derivative of the human glucocorticoid receptor expressed in yeast.

1990 • 77 citations

Novel Egr/NF-AT composite sites mediate activation of the CD95 (APO-1/Fas) ligand promoter in response to T cell stimulation

1999 • 73 citations

Glucocorticoids rescue CD4+ T lymphocytes from activation-induced apoptosis triggered by HIV-1

1995 • 51 citations

Targets of activated steroid hormone receptors: basal transcription factors and receptor interacting proteins

1998 • 35 citations

Utilization of an NF-ATp Binding Promoter Element for EGR3 Expression in T Cells but Not Fibroblasts Provides a Molecular Model for the Lymphoid Cell-Specific Effect of Cyclosporin A

1998 • 28 citations

A novel 77‐residue peptide from porcine brain contains a leucine‐zipper motif and is recognized by an antiserum to delta‐sleep‐inducing peptide

1993 • 23 citations