Transcriptional Regulation of the Human FasL Promoter-Enhancer Region

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis

1992 • 2,932 citations

Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family

1993 • 2,546 citations

Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege

1995 • 2,028 citations

The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death

1994 • 1,920 citations

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

1995 • 1,662 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Fas(CD95)/FasL interactions required for programmed cell death after T-cell activation

1995 • 1,549 citations

Dominant interfering fas gene mutations impair apoptosis in a human autoimmune lymphoproliferative syndrome

1995 • 1,477 citations

Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas

1995 • 1,346 citations

Mutations in Fas Associated with Human Lymphoproliferative Syndrome and Autoimmunity

1995 • 1,306 citations

A role for CD95 ligand in preventing graft rejection

1995 • 1,184 citations

Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120

1995 • 983 citations

Fas ligand mediates activation-induced cell death in human T lymphocytes.

1995 • 949 citations

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

1992 • 865 citations

Metalloproteinase-mediated release of human Fas ligand.

1995 • 835 citations

The fas antigen is involved in peripheral but not thymic deletion of T lymphocytes in T cell receptor transgenic mice

1994 • 708 citations

Fas ligand in human serum

1996 • 682 citations

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1995 • 656 citations

Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils.

1996 • 574 citations

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1994 • 523 citations

Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease.

1996 • 473 citations

Hyperproliferation and Dysregulation ofIL-4 Expression in NF-ATp-Deficient Mice

1996 • 456 citations

Prevention of Islet Allograft Rejection with Engineered Myoblasts Expressing FasL in Mice

1996 • 456 citations

Human Fas ligand: gene structure, chromosomal location and species specificity

1994 • 435 citations

Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?

1997 • 403 citations

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

1996 • 394 citations

Fas-mediated cytotoxicity by freshly isolated natural killer cells.

1995 • 372 citations

Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B.

1994 • 334 citations

The Roles of Fas/APO-1 (CD95) and TNF in Antigen-Induced Programmed Cell Death in T Cell Receptor Transgenic Mice

1996 • 325 citations

Contenders in FasL/TNF death signaling

1995 • 319 citations

Upregulation of Fas ligand expression by human immunodeficiency virus in human macrophages mediates apoptosis of uninfected T lymphocytes

1996 • 316 citations

Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.

1994 • 294 citations

Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain.

1996 • 283 citations

Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

1995 • 258 citations

The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation.

1992 • 258 citations

Macrophage-dependent Apoptosis of CD4+ T Lymphocytes from HIV-infected Individuals Is Mediated by FasL and Tumor Necrosis Factor

1997 • 242 citations

Die and Let Live: Eliminating Dangerous Lymphocytes

1996 • 242 citations

Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids.

1995 • 230 citations

Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoter.

1993 • 202 citations

Cell-Type-Specific Regulation of the Human Tumor Necrosis Factor Alpha Gene in B Cells and T Cells by NFATp and ATF-2/JUN

1996 • 189 citations

Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events.

1997 • 167 citations

Fc receptor-induced expression of Fas ligand on activated NK cells facilitates cell-mediated cytotoxicity and subsequent autocrine NK cell apoptosis.

1996 • 129 citations

HIV‐1 upregulates Fas ligand expression in CD4⁺ T cells in vitro and in vivo : association with Fas‐mediated apoptosis and modulation by aurintricarboxylic acid

1996 • 105 citations

Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells.

1994 • 92 citations

Role of apoptosis in HIV disease pathogenesis

1995 • 79 citations

Contribution of Fas ligand to cardiac allograft rejection

1996 • 61 citations

Regulation of I kappa B alpha and p105 in monocytes and macrophages persistently infected with human immunodeficiency virus

1995 • 59 citations

Distinct signaling properties identify functionally different CD4 epitopes

1995 • 53 citations

Role of cytokines in alveolar macrophage accessory cell function in HIV-infected individuals.

1992 • 49 citations

Inhibitory effect of the immunosuppressant FK506 on apoptotic cell death induced by HIV-1 gp120

1995 • 27 citations