Rapid turnover of the CD3ζ chain independent of the TCR-CD3 complex in normal T cells

Signal transduction by lymphocyte antigen receptors

1994 • 2,145 citations

MHC-dependent antigen processing and peptide presentation: Providing ligands for T lymphocyte activation

1994 • 1,448 citations

Assembly, Transport, and Function of MHC Class II Molecules

1994 • 791 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line.

1984 • 504 citations

Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins

1988 • 488 citations

Loss of T-cell receptor zeta chain and p56lck in T-cells infiltrating human renal cell carcinoma.

1993 • 385 citations

The T Cell Antigen Receptor: Insights into Organelle Biology

1990 • 361 citations

Failure to synthesize the T Cell CD3-? chain: Structure and function of a partial T cell receptor complex

1988 • 351 citations

Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma.

1993 • 344 citations

Identification of the components of the murine T cell antigen receptor complex

1985 • 333 citations

Genetic and Mutational Analysis of the T-Cell Antigen Receptor

1990 • 275 citations

Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors

1990 • 249 citations

Retention of Unassembled Components of Integral Membrane Proteins by Calnexin

1994 • 243 citations

T cell development in mice lacking the CD3-zeta/eta gene.

1993 • 235 citations

Building a multichain receptor: synthesis, degradation, and assembly of the T-cell antigen receptor.

1987 • 232 citations

Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly.

1989 • 228 citations

T Cell Development in Mice that Lack the ζ Chain of the T Cell Antigen Receptor Complex

1993 • 217 citations

A T3-like protein complex associated with the antigen receptor on murine T cells

1986 • 213 citations

Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine.

1993 • 186 citations

Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation.

1987 • 185 citations

Developmental and functional impairment of T cells in mice lacking CD3 zeta chains.

1993 • 164 citations

Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex

1987 • 159 citations

Activated macrophages induce structural abnormalities of the T cell receptor-CD3 complex.

1995 • 150 citations

Disulfide linkage of the zeta and eta chains of the T cell receptor. Possible identification of two structural classes of receptors.

1988 • 146 citations

Assembly of the human T cell receptor-CD3 complex takes place in the endoplasmic reticulum and involves intermediary complexes between the CD3-gamma.delta.epsilon core and single T cell receptor alpha or beta chains.

1988 • 142 citations

Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment.

1988 • 139 citations

Internalization and cycling of the T cell antigen receptor. Role of protein kinase C.

1987 • 133 citations

Role of the zeta chain in the expression of the T cell antigen receptor: genetic reconstitution studies.

1989 • 128 citations

Transmembrane signalling through the T-cell-receptor-CD3 complex

1993 • 98 citations

Evidence for protein tyrosine kinase involvement in ligand-induced TCR/CD3 internalization and surface redistribution.

1994 • 88 citations

The gamma and epsilon subunits of the CD3 complex inhibit pre-Golgi degradation of newly synthesized T cell antigen receptors.

1990 • 81 citations

T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes.

1992 • 72 citations

Preferential usage of the Fc receptor gamma chain in the T cell antigen receptor complex by gamma/delta T cells localized in epithelia.

1994 • 69 citations

Cell surface T3 expression requires the presence of both alpha- and beta-chains of the T cell receptor.

1987 • 58 citations

High Frequency of Cancer Patients with Abnormal Assembly of the T Cell Receptor‐CD3 Complex in Peripheral Blood T Lymphocytes

1994 • 52 citations

Association and dissociation of the murine T cell receptor associated protein (TRAP). Early events in the biosynthesis of a multisubunit receptor.

1988 • 49 citations

TCR isoform containing the Fc receptor γ chain exhibits structural and functional differences from isoform containing CD3ξ

1993 • 28 citations

Different cytoplasmic structure of the CD3ζ family dimer modulates the activation signal and function of T cells

1994 • 18 citations

Activation of Phospholipase C-γ1 through Transfected Platelet-Derived Growth Factor Receptor Enhances Interleukin 2 Production upon Antigen Stimulation in a T-Cell Line

1994 • 7 citations

Activation of phospholipase C-gamma 1 through transfected platelet-derived growth factor receptor enhances interleukin 2 production upon antigen stimulation in a T-cell line.

1994 • 4 citations