Requirement for p38α in Erythropoietin Expression

Current protocols in molecular biology

1988 • 7,584 citations

Real time quantitative PCR.

1996 • 6,155 citations

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

1994 • 2,659 citations

Cellular and developmental control of O₂ homeostasis by hypoxia-inducible factor 1α

1998 • 2,392 citations

HIF-1alpha is required for solid tumor formation and embryonic vascularization

1998 • 1,567 citations

Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development

1998 • 1,551 citations

An Osmosensing Signal Transduction Pathway in Yeast

1993 • 1,252 citations

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1997 • 1,229 citations

Jak2 Is Essential for Signaling through a Variety of Cytokine Receptors

1998 • 1,155 citations

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

1995 • 1,027 citations

Jak2 Deficiency Defines an EssentialDevelopmental Checkpoint in DefinitiveHematopoiesis

1998 • 904 citations

The Jnk1 and Jnk2 Protein Kinases Are Required for Regional Specific Apoptosis during Early Brain Development

1999 • 888 citations

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

1999 • 827 citations

p42/p44 Mitogen-activated Protein Kinases Phosphorylate Hypoxia-inducible Factor 1α (HIF-1α) and Enhance the Transcriptional Activity of HIF-1

1999 • 777 citations

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

1999 • 772 citations

Mitogen-activated protein kinase cascades and regulation of gene expression

1996 • 759 citations

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.

1992 • 650 citations

Defective Thymocyte Maturation in p44 MAP Kinase (Erk 1) Knockout Mice

1999 • 641 citations

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1990 • 611 citations

Defective T Cell Differentiation in the Absence of Jnk1

1998 • 590 citations

Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast

1995 • 578 citations

Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells.

1994 • 574 citations

Essential Role of p38α MAP Kinase in Placental but Not Embryonic Cardiovascular Development

2000 • 509 citations

p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes

1999 • 495 citations

p38 and Extracellular Signal-Regulated Kinases Regulate the Myogenic Program at Multiple Steps

2000 • 470 citations

p38 Mitogen-activated Protein Kinase Pathway Promotes Skeletal Muscle Differentiation

1999 • 444 citations

Conjugation, meiosis, and the osmotic stress response are regulated by Spc1 kinase through Atf1 transcription factor in fission yeast.

1996 • 419 citations

Role of CSBP/p38/RK stress response kinase in LPS and cytokine signaling mechanisms

1996 • 396 citations

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2

1999 • 357 citations

Stabilization of Interleukin-2 mRNA by the c-Jun NH ₂ -Terminal Kinase Pathway

1998 • 353 citations

Regulation of the Erythropoietin Gene

1999 • 311 citations

Regulation of the erythropoietin gene

1993 • 310 citations

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development

1999 • 305 citations

Regulation of the Erythropoietin Gene

1989 • 305 citations

Functions of c-Jun in Liver and Heart Development

1999 • 274 citations

Deficiency of the Stress Kinase P38α Results in Embryonic Lethality

2000 • 272 citations

Three stages of erythropoietic progenitor cell differentiation distinguished by a number of physical and biologic properties

1978 • 269 citations

T Cell Proliferation in Response to Interleukins 2 and 7 Requires p38MAP Kinase Activation

1997 • 254 citations

Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells

2000 • 230 citations

Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans

1990 • 210 citations

Erythropoietin mRNA levels are governed by both the rate of gene transcription and posttranscriptional events

1991 • 202 citations

Identification of Newly Transcribed <scp>RNA</scp>

2007 • 192 citations

Selective Activation of p38α and p38γ by Hypoxia

1999 • 179 citations

Discrete Roles of the Spc1 Kinase and the Atf1 Transcription Factor in the UV Response of Schizosaccharomyces pombe

1997 • 176 citations

Stem Cell Emergence and Hemopoietic Activity Are Incompatible in Mouse Intraembryonic Sites

1999 • 173 citations

Hemopoietic Growth Factors with the Exception of Interleukin-4 Activate the p38 Mitogen-activated Protein Kinase Pathway

1997 • 172 citations

Stress signal, mediated by a Hogl‐like MAP kinase, controls sexual development in fission yeast

1996 • 162 citations

The p38 MAP Kinase Pathway and Its Biological Function

1998 • 162 citations

Regulated Expression of Globin Chains and the Erythroid Transcription Factor GATA-1 during Erythropoiesis in the Developing Mouse

1990 • 153 citations

Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse.

1990 • 105 citations

Activation of p38 MAP Kinase Pathway by Erythropoietin and Interleukin-3

1997 • 89 citations

CD44 isoforms in normal and leukemic hematopoiesis

1999 • 65 citations

Biochemical monitoring of fetal distress with serum-immunoreactive erythropoietin

1996 • 16 citations

Assays for JNK and p38 Mitogen-Activated Protein Kinases

2000 • 13 citations