Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells¹

2010 • 4,125 citations

Purification and Characterization of Mouse Hematopoietic Stem Cells

1988 • 2,856 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

1985 • 1,983 citations

Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand.

1987 • 1,627 citations

Stem cell factor is encoded at the SI locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor

1990 • 1,448 citations

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1988 • 1,390 citations

The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

1988 • 1,336 citations

The hematopoietic growth factor KL is encoded by the SI locus and is the ligand of the c-kit receptor, the gene product of the W locus

1990 • 1,208 citations

Hereditary Anemias of the Mouse: A Review for Geneticists

1979 • 1,141 citations

Identification of a ligand for the c-kit proto-oncogene

1990 • 970 citations

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1990 • 870 citations

Identification, purification, and biological characterization of hematopoietic stem cell factor from buffalo rat liver-conditioned medium

1990 • 837 citations

Primary structure and functional expression of rat and human stem cell factor DNAs

1990 • 779 citations

The kit ligand: A cell surface molecule altered in steel mutant fibroblasts

1990 • 777 citations

Expression and function of c-kit in hemopoietic progenitor cells.

1991 • 756 citations

Primary structure of c-kit: relationship with the CSF-1/PDGF receptor kinase family-oncogenic activation of v-kit involves deletion of extracellular domain and C terminus.

1988 • 727 citations

Mast cell growth factor maps near the steel locus on mouse chromosome 10 and is deleted in a number of steel alleles

1990 • 632 citations

Multiple hematopoietic lineages develop from embryonic stem (ES) cells in culture

1991 • 615 citations

A developmental switch in thymic lymphocyte maturation potential occurs at the level of hematopoietic stem cells

1990 • 611 citations

Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W.

1990 • 599 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Clonal analysis of hematopoietic stem-cell differentiation in vivo.

1991 • 379 citations

Isolation of murine pluripotent hemopoietic stem cells.

1984 • 333 citations

Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression.

1991 • 332 citations

Isolation of two early B lymphocyte progenitors from mouse marrow: A committed Pre-Pre-B cell and a clonogenic Thy-1lo hematopoietic stem cell

1986 • 330 citations

Cellular and developmental properties of fetal hematopoietic stem cells

1990 • 317 citations

Stable Antibody-Producing Murine Hybridomas

1983 • 189 citations

Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors.

1991 • 180 citations

c-kit protein, a transmembrane kinase: identification in tissues and characterization.

1988 • 167 citations

The effect of recombinant mast cell growth factor on purified murine hematopoietic stem cells.

1991 • 157 citations

Isolation of haemopoietic spleen colony forming cells.

1986 • 76 citations

c-kit Protein, a Transmembrane Kinase: Identification in Tissues and Characterization

1988 • 22 citations