Assays for JNK and p38 Mitogen-Activated Protein Kinases

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

1995 • 5,334 citations

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells

1994 • 2,659 citations

The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases

1995 • 2,441 citations

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin‐1

1995 • 2,080 citations

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain.

1993 • 1,902 citations

ERKs: A family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

1991 • 1,901 citations

How MAP Kinases Are Regulated

1995 • 1,742 citations

A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins

1994 • 1,684 citations

Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

1995 • 1,453 citations

Selective interaction of JNK protein kinase isoforms with transcription factors.

1996 • 1,333 citations

Transcriptional Regulation by Extracellular signals: Mechanisms and Specificity

1995 • 1,287 citations

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

1997 • 1,229 citations

Identification of a Dual Specificity Kinase That Activates the Jun Kinases and p38-Mpk2

1995 • 775 citations

Characterization of the Structure and Function of the Fourth Member of p38 Group Mitogen-activated Protein Kinases, p38δ

1997 • 482 citations

Cooperation between Syk and Rac1 Leads to Synergistic JNK Activation in T Lymphocytes

1998 • 125 citations

Molecular Cloning and Characterization of Human JNKK2, a Novel Jun NH₂-Terminal Kinase-Specific Kinase

1997 • 108 citations