Lamotrigine

Lifetime and 12-Month Prevalence of DSM-III-R Psychiatric Disorders in the United States

1994 • 12,456 citations

The Long-term Natural History of the Weekly Symptomatic Status of Bipolar I Disorder

2002 • 2,037 citations

The de Facto US Mental and Addictive Disorders Service System

1993 • 2,002 citations

A Double-Blind Placebo-Controlled Study of Lamotrigine Monotherapy in Outpatients With Bipolar I Depression

1999 • 1,056 citations

A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Manic or Hypomanic Patients With Bipolar I Disorder

2003 • 661 citations

A Placebo-Controlled 18-Month Trial of Lamotrigine and Lithium Maintenance Treatment in Recently Depressed Patients With Bipolar I Disorder

2003 • 629 citations

Pharmacological Studies on Lamotrigine, A Novel Potential Antiepileptic Drug

1986 • 558 citations

A Double-Blind, Placebo-Controlled, Prophylaxis Study of Lamotrigine in Rapid-Cycling Bipolar Disorder

2000 • 492 citations

A Placebo-Controlled Study of Lamotrigine and Gabapentin Monotherapy in Refractory Mood Disorders

2000 • 455 citations

Outcomes of Add‐on Treatment with Lamotrigine in Partial Epilepsy

1993 • 339 citations

Rash in Multicenter Trials of Lamotrigine in Mood Disorders

2002 • 334 citations

Lamotrigine

1993 • 300 citations

Lamotrigine in Pregnancy: Pharmacokinetics During Delivery, in the Neonate, and During Lactation

2000 • 292 citations

Lamotrigine, a new anticonvulsant: Pharmacokinetics in normal humans

1987 • 273 citations

Suicide and Bipolar Disorder

2019 • 264 citations

Lamotrigine Clinical Pharmacokinetics

1993 • 237 citations

MRI findings in patients with affective disorder: a meta‐analysis

1997 • 229 citations

Lamotrigine

2000 • 227 citations

Lamotrigine inhibits Ca2+ currents in cortical neurons: functional implications

1996 • 204 citations

Cyclooxygenase‐2 Induction in Cerebral Cortex: An Intracellular Response to Synaptic Excitation

1996 • 201 citations

Lamotrigine

1995 • 197 citations

Spectrum of Activity of Lamotrigine in Treatment-Refractory Bipolar Disorder

1999 • 170 citations

Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: Implications for neurodegenerative diseases

1996 • 157 citations

Cerebroprotective Effect of Lamotrigine After Focal Ischemia in Rats

1995 • 148 citations

Lamotrigine (BW430C), a potential anticonvulsant. Effects on the central nervous system in comparison with phenytoin and diazepam.

1985 • 144 citations

Neurochemical and Behavioral Aspects of Lamotrigine

1991 • 142 citations

The risk of suicide in patients with bipolar disorders.

1999 • 134 citations

Lamotrigine: single-dose pharmacokinetics and initial 1 week experience in refractory epilepsy

1987 • 133 citations

Neuroprotective Properties of the Novel Antiepileptic Lamotrigine in a Gerbil Model of Global Cerebral Ischemia

1995 • 132 citations

Pharmacokinetics and safety of lamotrigine (Lamictal®) in patients with epilepsy

1991 • 130 citations

Cellular and Molecular Actions of Lamotrigine: Possible Mechanisms of Efficacy in Bipolar Disorder

1998 • 130 citations

Lamotrigine inhibits monoamine uptake in vitro and modulates 5-hydroxytryptamine uptake in rats

1998 • 128 citations

Clinical Pharmacology of Lamotrigine

1991 • 126 citations

Bidirectional interaction of valproate and lamotrigine in healthy subjects*

1996 • 123 citations

Inhibition of N-type calcium currents by lamotrigine in rat amygdalar neurones

1996 • 122 citations

Reduced suicide risk during lithium maintenance treatment.

2000 • 121 citations

Comparative study of voltage-sensitive sodium channel blockers in focal ischaemia and electric convulsions in rodents

1994 • 116 citations

Lamotrigine: Pharmacokinetics

1997 • 115 citations

Safety and Tolerability of Lamotrigine for Bipolar Disorder

2004 • 109 citations

Clinical predictors of response to lamotrigine and gabapentin monotherapy in refractory affective disorders

2002 • 100 citations

Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders?

2002 • 94 citations

Neuroprotective effects of lamotrigine in global ischemia in gerbils. A histological, in vivo microdialysis and behavioral study

1995 • 91 citations

Clinical Pharmacokinetics of Newer Antiepileptic Drugs

1996 • 86 citations

Seizure Severity and the Quality of Life

1993 • 79 citations

Lamotrigine protects against kainate but not ibotenate lesions in rat striatum

1990 • 77 citations

Pharmacokinetic Interactions of the New Antiepileptic Drugs

1996 • 74 citations

Bipolar Depression

2003 • 69 citations

Pharmacokinetics of lamotrigine in patients with renal impairment: influence of haemodialysis.

1993 • 65 citations

A calcium antagonistic effect of the new antiepileptic drug lamotrigine

1997 • 58 citations

Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers

1997 • 58 citations

Prevention by lamotrigine, MK-801 and Nω-nitro-l-arginine methyl ester of motoneuron cell death after neonatal axotomy

1996 • 57 citations

Long-Term Tolerability, Pharmacokinetic and Preliminary Efficacy Study of Lamotrigine in Patients with Resistant Partial Seizures

1989 • 55 citations

Comparative Efficacy and Tolerability of Drug Treatments for Bipolar Disorder

2001 • 53 citations

The effects of lamotrigine on the pharmacokinetics of lithium

2000 • 47 citations

Lamotrigine may limit pathological excitation in the hippocampus by modulating a transient potassium outward current

1998 • 45 citations

Lamotrigine Drug Interactions in a TDM Material

1999 • 41 citations

Lamotrigine in the treatment of bipolar disorder

2002 • 41 citations

Saliva and Serum Concentration of Lamotrigine in Patients With Epilepsy

2000 • 39 citations

Comparison of the pharmacokinetics of lamotrigine in patients with chronic renal failure and healthy volunteers

1997 • 36 citations

Impact of clinical variables on illness time course in mood disorders

2000 • 34 citations

Effects of Steady‐State Bupropion on the Pharmacokinetics of Lamotrigine in Healthy Subjects

2000 • 30 citations

Lamotrigine Concentrations in Human Serum, Brain Tissue, and Tumor Tissue

1999 • 30 citations

Effect of lamotrigine on carbamazepine epoxide/carbamazepine serum concentration ratios in adult patients with epilepsy

1997 • 25 citations

Lamotrigine induced selective changes in 5-HT1A receptor mediated response in rat brain

2002 • 23 citations

Nonlinear mixed effects modeling of single dose and multiple dose data for an immediate release (IR) and a controlled release (CR) dosage form of alprazolam.

1997 • 21 citations

Effects of lamotrigine on the 5-HT1A receptor function in healthy human males

1998 • 18 citations

An electrophysiological analysis of the protective effects of felbamate, lamotrigine, and lidocaine on the functional recovery from in vitro ischemia in rat neocortical slices

1998 • 18 citations

Marinobufagenin (MBG) suppression of ethanol-seeking behavior is associated with inhibition of brain cortex Na/K-ATPase in mice

2002 • 14 citations

THE DISPOSITION OF LAMOTRIGINE THROUGHOUT PREGNANCY

1999 • 9 citations

The effect of parenteral imipramine on the oral absorption of lamotrigine in rats

1997 • 4 citations

86 LAMOTRIGINE & THERAPEUTIC DRUG MONITORING

1997 • 2 citations

84 LAMOTRIGIN DRUG INTERACTIONS IN A TDM MATERIAL

1997 • 1 citations