Analysis of the Intron–Exon Organization of the Human Multidrug-Resistance Protein Gene (MRP) and Alternative Splicing of Its mRNA

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Current protocols in molecular biology

1988 • 7,584 citations

Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA

1989 • 7,327 citations

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

1992 • 3,039 citations

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells

1986 • 1,903 citations

Cloning of the β Cell High-Affinity Sulfonylurea Receptor: a Regulator of Insulin Secretion

1995 • 1,310 citations

Mammalian multidrug resistance gene: Complete cDNA sequence indicates strong homology to bacterial transport proteins

1986 • 1,058 citations

Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene

1996 • 827 citations

Mutations in the Sulfonylurea Receptor Gene in Familial Persistent Hyperinsulinemic Hypoglycemia of Infancy

1995 • 812 citations

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

1993 • 760 citations

Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance

1986 • 680 citations

cDNA Cloning of the Hepatocyte Canalicular Isoform of the Multidrug Resistance Protein, cMrp, Reveals a Novel Conjugate Export Pump Deficient in Hyperbilirubinemic Mutant Rats

1996 • 641 citations

Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.

1994 • 621 citations

A survey on intron and exon lengths

1988 • 569 citations

Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump.

1996 • 569 citations

Multidrug Resistance Protein (MRP)-mediated Transport of Leukotriene C4 and Chemotherapeutic Agents in Membrane Vesicles

1996 • 555 citations

When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells.

1995 • 515 citations

Biology of the multidrug resistance-associated protein, MRP

1996 • 367 citations

Expression of the Gene for Multidrug-Resistance–Associated Protein and Outcome in Patients with Neuroblastoma

1996 • 321 citations

ATP-dependent glutathione disulphide transport mediated by the MRP gene-encoded conjugate export pump

1996 • 290 citations

A splicing-dependent regulatory mechanism that detects translation signals.

1996 • 278 citations

Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.

1990 • 271 citations

ATP-dependent 17β-Estradiol 17-(β-D-Glucuronide) Transport by Multidrug Resistance Protein (MRP)

1996 • 265 citations

Membrane topology distinguishes a subfamily of the ATP‐binding cassette (ABC) transporters

1997 • 237 citations

Isolation of PEBP2 alpha B cDNA representing the mouse homolog of human acute myeloid leukemia gene, AML1.

1993 • 229 citations

Membrane Topology and Glycosylation of the Human Multidrug Resistance-associated Protein

1996 • 209 citations

ATP-Dependent Transport of Aflatoxin B₁and Its Glutathione Conjugates by the Product of the Multidrug Resistance Protein (MRP) Gene

1997 • 189 citations

Translation to near the distal end of the penultimate exon is required for normal levels of spliced triosephosphate isomerase mRNA.

1990 • 159 citations

Characterization of the ATP‐dependent leukotriene C₄ export carrier in mastocytoma cells

1994 • 157 citations

Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines.

1993 • 153 citations

Human genes containing polymorphic trinucleotide repeats

1992 • 151 citations

Mapping of cystic fibrosis transmembrane conductance regulator membrane topology by glycosylation site insertion

1994 • 134 citations

Trinucleotide repeat expansions and human genetic disease

1994 • 116 citations

Structure and expression of the messenger RNA encoding the murine multidrug resistance protein, an ATP-binding cassette transporter.

1996 • 108 citations

Expression of the multidrug resistance-associated protein (MRP) gene in non-small-cell lung cancer

1995 • 107 citations

Location of a protease-hypersensitive region in the multidrug resistance protein (MRP) by mapping of the epitope of MRP-specific monoclonal antibody QCRL-1.

1996 • 106 citations

Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: prognostic implications

1994 • 105 citations

Cloning and sequence analysis of the promoter region of the MRP gene of HL60 cells isolated for resistance to adriamycin.

1994 • 101 citations

Inactivation of the first nucleotide-binding fold of the sulfonylurea receptor, and familial persistent hyperinsulinemic hypoglycemia of infancy.

1996 • 76 citations

Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer

1996 • 76 citations

MRP is frequently expressed in human lung-cancer cell lines, in non-small-cell lung cancer and in normal lung

1996 • 61 citations

The 1991 Merck Frosst Award. Multidrug resistance in small cell lung cancer

1992 • 55 citations

Mechanisms of MRP over‐expression in four human lung‐cancer cell lines and analysis of the MRP amplicon

1995 • 53 citations

Evidence that SP1 Modulates Transcriptional Activity of the Multidrug Resistance-Associated Protein Gene

1996 • 47 citations

Evolution of the ATP-binding-cassette transmembrane transporters of vertebrates.

1994 • 45 citations

Expression of a putative ATP-binding cassette region, homologous to that in multidrug resistance-associated protein (MRP), is hereditarily defective in Eisai hyperbilirubinemic rats (EHBR)

1996 • 38 citations

Molecular Genetics of Drug Resistance

2024 • 29 citations

Analysis of Alternative Splicing Patterns in the Cystic Fibrosis Transmembrane Conductance Regulator Gene Using mRNA Derived from Lymphoblastoid Cells of Cystic Fibrosis Patients

1996 • 13 citations