Membrane lipids as signaling molecules

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Phosphoinositides in cell regulation and membrane dynamics

2006 • 2,604 citations

Role of Oxidative Modifications in Atherosclerosis

2004 • 2,558 citations

The emerging field of lipidomics

2005 • 1,240 citations

How proteins produce cellular membrane curvature

2005 • 1,223 citations

Type I phosphatidylinositol kinase makes a novel inositol phospholipid, phosphatidylinositol-3-phosphate

1988 • 1,027 citations

Lymphocyte Sequestration Through S1P Lyase Inhibition and Disruption of S1P Gradients

2005 • 772 citations

The Saccharomyces cerevisiae Lipin Homolog Is a Mg2+-dependent Phosphatidate Phosphatase Enzyme*

2006 • 534 citations

Signalling through Class I PI3Ks in mammalian cells

2006 • 529 citations

Autotaxin, a Secreted Lysophospholipase D, Is Essential for Blood Vessel Formation during Development

2006 • 524 citations

FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

2004 • 518 citations

Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly

2006 • 513 citations

GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission

2006 • 480 citations

Phospholipid Metabolism Regulated by a Transcription Factor Sensing Phosphatidic Acid

2004 • 475 citations

Docosahexaenoic acid: A positive modulator of Akt signaling in neuronal survival

2005 • 450 citations

A biosynthetic pathway for anandamide

2006 • 446 citations

Regulation of cholesterol and sphingomyelin metabolism by amyloid-β and presenilin

2005 • 416 citations

Phosphatidic acid- and phosphatidylserine-binding proteins

2006 • 363 citations

Phosphatidylserine recognition by phagocytes: a view to a kill

2006 • 326 citations

Receptor Activation Alters Inner Surface Potential During Phagocytosis

2006 • 324 citations

Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: Insights from vesicle recycling in nerve terminals

2004 • 322 citations

Free Radicals, Mitochondria, and Oxidized Lipids

2006 • 316 citations

Phosphorylation of Proteins by Inositol Pyrophosphates

2004 • 299 citations

C1 domains exposed: From diacylglycerol binding to protein–protein interactions

2006 • 296 citations

Emerging medicinal roles for lysophospholipid signaling

2006 • 240 citations

Diacylglycerol and Phosphatidate Generated by Phospholipases C and D, Respectively, Have Distinct Fatty Acid Compositions and Functions

1997 • 200 citations

Trans-cyclopropanation of mycolic acids on trehalose dimycolate suppresses Mycobacterium tuberculosis-induced inflammation and virulence

2006 • 192 citations

Apoptotic interactions of cytochrome c: Redox flirting with anionic phospholipids within and outside of mitochondria

2006 • 175 citations

Neutral sphingomyelinase 2 ( smpd3 ) in the control of postnatal growth and development

2005 • 163 citations

Role for Mammalian Neutral Sphingomyelinase 2 in Confluence-induced Growth Arrest of MCF7 Cells

2004 • 155 citations

nSMase2 activation and trafficking are modulated by oxidative stress to induce apoptosis

2006 • 120 citations

New Insights into Endocannabinoid Degradation and its Therapeutic Potential

2006 • 110 citations

Dynamin Is Membrane-Active: Lipid Insertion Is Induced by Phosphoinositides and Phosphatidic Acid

2000 • 102 citations

Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium

2005 • 101 citations

Lipid oxidation in atherogenesis: an overview

2004 • 86 citations

Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium

2005 • 67 citations

Neutral Sphingomyelinase 1 Deficiency in the Mouse Causes No Lipid Storage Disease

2002 • 62 citations

Role of lipid trimming and CD1 groove size in cellular antigen presentation

2006 • 49 citations

Membrane targeting and remodeling through phosphoinositide‐binding domains

2006 • 45 citations

Metabolic Profiling of Patients with Schizophrenia

2006 • 40 citations

Structural Determinants for Phosphatidic Acid Regulation of Phospholipase C-β1

2006 • 31 citations

Dual Phospholipase C/Diacylglycerol Requirement for Protein Kinase D1 Activation in Lymphocytes

2004 • 28 citations

How T lymphocytes recognize lipid antigens

2006 • 15 citations

Targeted lipidomics: Signaling lipids and drugs of abuse

2005 • 12 citations