Phospholipid Metabolism Regulated by a Transcription Factor Sensing Phosphatidic Acid

A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

1999 • 1,311 citations

Phosphatidic Acid-Mediated Mitogenic Activation of mTOR Signaling

2001 • 1,012 citations

Molecular machinery for non-vesicular trafficking of ceramide

2003 • 994 citations

Yeast Cells Provide Insight into Alpha-Synuclein Biology and Pathobiology

2003 • 790 citations

A conserved ER targeting motif in three families of lipid binding proteins and in Opi1p binds VAP

2003 • 588 citations

Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing

2000 • 561 citations

Structural organization of the endoplasmic reticulum

2002 • 507 citations

Electrospray Ionization Tandem Mass Spectrometry (Esi-Ms/Ms) Analysis of the Lipid Molecular Species Composition of Yeast Subcellular Membranes Reveals Acyl Chain-Based Sorting/Remodeling of Distinct Molecular Species En Route to the Plasma Membrane

1999 • 482 citations

START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins

1999 • 398 citations

Binding of the PX domain of p47phox to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

2002 • 308 citations

Regulation of SREBP Processing and Membrane Lipid Production by Phospholipids in Drosophila

2002 • 305 citations

Genetic regulation of phospholipid biosynthesis in Saccharomyces cerevisiae

1996 • 231 citations

Expression of the Saccharomyces cerevisiae Inositol-1-Phosphate Synthase (INO1) Gene is Regulated by Factors That Affect Phospholipid Synthesis

1986 • 220 citations

Regulation of the desaturation of fatty acids and its role in tolerance to cold and salt stress

2002 • 197 citations

The OPI1 gene of Saccharomyces cerevisiae, a negative regulator of phospholipid biosynthesis, encodes a protein containing polyglutamine tracts and a leucine zipper.

1991 • 180 citations

Genetic Regulation of Phospholipid Metabolism: Yeast as a Model Eukaryote

1998 • 165 citations

TAPAS-1, a Novel Microdomain within the Unique N-terminal Region of the PDE4A1 cAMP-specific Phosphodiesterase That Allows Rapid, Ca2+-triggered Membrane Association with Selectivity for Interaction with Phosphatidic Acid

2002 • 158 citations

Relocalization of Phospholipase D Activity Mediates Membrane Formation During Meiosis

1998 • 137 citations

Differential Binding of Traffic-related Proteins to Phosphatidic Acid- or Phosphatidylinositol (4,5)- Bisphosphate-coupled Affinity Reagents

2001 • 128 citations

Analysis of sequences in theINO1promoter that are involved in its regulation by phospholipid precursors

1991 • 119 citations

Binding of Phosphatidic Acid to the Protein-Tyrosine Phosphatase SHP-1 as a Basis for Activity Modulation

1999 • 117 citations

The cAMP-specific Phosphodiesterase PDE4D3 Is Regulated by Phosphatidic Acid Binding

2000 • 116 citations

The negative regulator Opi1 of phospholipid biosynthesis in yeast contacts the pleiotropic repressor Sin3 and the transcriptional activator Ino2

2001 • 113 citations

Tight Binding Inhibition of Protein Phosphatase-1 by Phosphatidic Acid

2002 • 83 citations

Functional Analysis of a Phosphatidic Acid Binding Domain in Human Raf-1 Kinase

2003 • 79 citations

Molecular cloning of the gene encoding CDPdiacylglycerol–inositol 3‐phosphatidyl transferase in Saccharomyces cerevisiae

1984 • 79 citations

Phosphorylation of the Yeast Phospholipid Synthesis Regulatory Protein Opi1p by Protein Kinase C

2001 • 78 citations

Role of the Yeast VAP Homolog, Scs2p, in INO1 Expression and Phospholipid Metabolism

2003 • 44 citations