Variable Incidence of Cyclosporine and FK-506 Neurotoxicity in Hematopoeitic Malignancies and Marrow Conditions After Allogeneic Bone Marrow Transplantation

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Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments]

1990 • 591 citations

Allogeneic marrow transplantation in patients with acute myeloid leukemia in first remission: a randomized trial of two irradiation regimens [see comments]

1990 • 525 citations

Central Nervous System Toxicity after Liver Transplantation

1987 • 500 citations

Total Therapy With Tandem Transplants for Newly Diagnosed Multiple Myeloma

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Posterior leukoencephalopathy without severe hypertension

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Cyclosporine-Induced Sympathetic Activation and Hypertension after Heart Transplantation

1990 • 423 citations

Hypoxia-induced vascular endothelial growth factor expression causes vascular leakage in the brain

2002 • 412 citations

Marrow transplantation for chronic myeloid leukemia: a randomized study comparing cyclophosphamide and total body irradiation with busulfan and cyclophosphamide

1994 • 373 citations

ASSOCIATION BETWEEN CYCLOSPORIN NEUROTOXICITY AND HYPOMAGNESAEMIA

1984 • 337 citations

Cyclosporine neurotoxicity and its relationship to hypertensive encephalopathy: CT and MR findings in 16 cases.

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Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome

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Cyclosporin-induced endothelial cell injury.

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Prognostic factors in allogeneic bone marrow transplantation for multiple myeloma.

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Reversible Posterior Leukoencephalopathy Syndrome: Evaluation with Diffusion-Tensor MR Imaging

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Chronic graft versus host disease: A syndrome of disordered immunity

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Prospective comparative trial of autologous versus allogeneic bone marrow transplantation in patients with non-Hodgkin's lymphoma

1994 • 233 citations

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1992 • 199 citations

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Modulation of acute graft-versus-host-disease after allogeneic bone marrow transplantation by tumor necrosis factor alpha (TNF alpha) release in the course of pretransplant conditioning: role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNF alpha (MAK 195F)

1995 • 198 citations

Microangiopathy in patients on cyclosporine prophylaxis who developed acute graft-versus-host disease after HLA-identical bone marrow transplantation

1989 • 197 citations

Endothelial cell gene expression in response to injury

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MR imaging of reversible cyclosporin A-induced neurotoxicity

1991 • 194 citations

Neurologic complications in allogeneic bone marrow transplant patients receiving cyclosporin.

1991 • 187 citations

IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation

1999 • 175 citations

Rapid decline of chronic myeloid leukemic cells in long-term culture due to a defect at the leukemic stem cell level.

1992 • 174 citations

Renal toxicity after allogeneic bone marrow transplantation: the combined effects of total-body irradiation and graft-versus-host disease.

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Quantitative assessment of diffusion abnormalities in posterior reversible encephalopathy syndrome.

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Proinflammatory cytokines and their role in the development of major transplant-related complications in the early phase after allogeneic bone marrow transplantation

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Cerebral blindness and encephalopathy with cyclosporin A toxicity

1987 • 148 citations

Graft-Versus-Leukemia Effect and Graft-Versus-Host Disease Can Be Differentiated by Cytotoxic Mechanisms in a Murine Model of Allogeneic Bone Marrow Transplantation

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Cyclosporin toxicity at therapeutic blood levels and cytochrome P-450 IIIA

1990 • 143 citations

Etiology of cortical and white matter lesions in cyclosporin-A and FK-506 neurotoxicity.

2001 • 142 citations

Salvage autologous or allogeneic transplantation for multiple myeloma refractory to or relapsing after a first-line autograft?

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Role of the Bone Marrow Microenvironment in Multiple Myeloma

2002 • 130 citations

Hemolytic-uremic syndrome following bone marrow transplantation in adults for hematologic malignancies

1991 • 127 citations

TNF alpha levels are increased during bone marrow transplantation conditioning in patients who develop acute GVHD.

1995 • 126 citations

CYCLOSPORINE-ASSOCIATED CENTRAL NERVOUS SYSTEM TOXICITY AFTER ALLOGENEIC BONE MARROW TRANSPLANTATION

1984 • 114 citations

Endothelial dysfunction after bone marrow transplantation: Increase of soluble thrombomodulin and PAI-1 in patients with multiple transplant-related complications

1998 • 107 citations

THE VASCULAR ENDOTHELIAL CELL ANTIGEN SYSTEM

1985 • 107 citations

Cyclosporine and tacrolimus–associated thrombotic microangiopathy

2000 • 105 citations

Elevated interleukin (IL)‐18 levels during acute graft‐versus‐host disease after allogeneic bone marrow transplantation

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Elevated Serum Cytokines Are Associated with Cytomegalovirus Infection and Disease in Bone Marrow Transplant Recipients

1999 • 95 citations

Transplantation-associated thrombotic microangiopathy: twenty-two years later

2002 • 90 citations

INTERLEUKIN-6 AND THE NETWORK OF SEVERAL CYTOKINES IN MULTIPLE MYELOMA: AN OVERVIEW OF CLINICAL AND EXPERIMENTAL DATA

2001 • 89 citations

Watershed Imaging Features and Clinical Vascular Injury in Cyclosporin A Neurotoxicity

1997 • 85 citations

De novo hemolytic uremic syndrome postrenal transplant after cytomegalovirus infection

1999 • 83 citations

High-dose cytarabine neurotoxicity: MR findings during the acute phase.

1993 • 82 citations

Hemolytic uremic syndrome following bone marrow transplantation.

1991 • 78 citations

Transplantation-associated thrombotic microangiopathy is associated with transplantation from unrelated donors, acute graft-versus-host disease and venoocclusive disease of the liver

2002 • 76 citations

Autoimmunity in 28 patients after allogeneic bone marrow transplantation: comparison with Sjögren syndrome and scleroderma

1987 • 75 citations

Serum levels of soluble IL-2 receptor, IL-12, IL-18, and IFN-γ in patients with acute graft-versus-host disease after allogeneic bone marrow transplantation

2000 • 75 citations

Vascular hyperpermeability induced by tumor necrosis factor and its augmentation by IL-1 and IFN-gamma is inhibited by selective depletion of neutrophils with a monoclonal antibody.

1990 • 71 citations

Rapid increase in blood-brain barrier permeability during severe hypoxia and metabolic inhibition

1986 • 71 citations

Pretransplantation conditioning influence on the occurrence of cyclosporine or FK-506 neurotoxicity in allogeneic bone marrow transplantation.

2004 • 66 citations

Thrombotic microangiopathy following allogeneic bone marrow transplantation is associated with intensive graft-versus-host disease prophylaxis

1998 • 66 citations

Complex Visual Hallucinations and Cyclosporine

1984 • 64 citations

Endothelial cell activation

1998 • 63 citations

Discordant maturation as the primary biological defect in chronic myelogenous leukemia.

1988 • 63 citations

Plasma exchange and vincristine in the treatment of hemolytic uremic syndrome/thrombotic thrombocytopenic purpura associated with bone marrow transplantation

1991 • 60 citations

Plasma von Willebrand factor antigen (vWF:AG) and thrombomodulin (TM) levels in adult thrombotic thrombocytopenic purpura/hemolytic uremic syndromes (TTP/HUS) and bone marrow transplant-associated thrombotic microangiopathy (BMT-TM)

1996 • 59 citations

Marrow transplantation for CML: the Seattle experience.

1996 • 59 citations

Allogeneic bone marrow transplantation for relapsed and refractory Hodgkin’s disease and non-Hodgkin’s lymphoma

1997 • 58 citations

Convulsions associated with cyclosporin A in renal transplant recipients.

1985 • 58 citations

ADULT RESPIRATORY DISTRESS SYNDROME AND CONVULSIONS ASSOCIATED WITH AMINISTRATION OF CYCLOSPORINE IN LIVER TRANSPLANT RECIPIENTS

1984 • 57 citations

Predicting the severity of graft-versus-host disease from interleukin-10 levels after bone marrow transplantation

1999 • 56 citations

Cyclosporin neurotoxicity in cardiac transplant recipients.

1988 • 56 citations

Haemostatic Properties of Human Pulmonary and Cerebral Microvascular Endothelial Cells

1997 • 55 citations

An early increase in serum levels of C-reactive protein is an independent risk factor for the occurrence of major complications and 100-day transplant-related mortality after allogeneic bone marrow transplantation

2002 • 50 citations

CYCLOSPORINE-ASSOCIATED CENTRAL NERVOUS SYSTEM TOXICITY AFTER RENAL TRANSPLANTATION

1985 • 49 citations

Cyclosporine A toxicity presenting with acute cerebellar edema and brainstem compression

1995 • 48 citations

Cyclosporin A-induced reversible cortical blindness.

1988 • 47 citations

Serum levels of cytokines after bone marrow transplantation: increased IL‐8 levels during severe veno‐occlusive disease of the liver

1997 • 45 citations

Pathophysiology of CML: Do defects in integrin function contribute to the premature circulation and massive expansion of the BCR/ABL positive clone?

1997 • 43 citations

Serum markers of graft-versus-host disease after bone marrow transplantation

2000 • 43 citations

Diagnostic value of hemostatic parameters in bone marrow transplant-associated thrombotic microangiopathy

1998 • 43 citations

Role of caspases 1 and 3 and Bcl-2-related molecules in endothelial cell apoptosis associated with thrombotic microangiopathies

1998 • 42 citations

Cortical blindness: a rare complication of cyclosporine therapy.

1990 • 40 citations

Endothelial cell activation in patients with systemic vasculitis

1994 • 39 citations

Mechanisms of endothelial cell injury in vasculitis

1994 • 39 citations

Cortical hyperintensity on proton density-weighted images: An MR sign of cyclosporine-related encephalopathy.

1996 • 39 citations

Impact of previous high-dose therapy on outcome after allografting for multiple myeloma

1999 • 38 citations

Chemoprevention of head and neck cancer

1993 • 37 citations

Generalised epileptic fits in renal transplant recipients given cyclosporin A.

1984 • 36 citations

CYCLOSPORINE CENTRAL NEUROTOXICITY FOLLOWING RENAL TRANSPLANTATION

1990 • 31 citations

The effect of human leukocyte antigen disparity on cyclosporine neurotoxicity after allogeneic bone marrow transplantation.

1998 • 30 citations

Busulfan and cyclophosphamide as a preparative regimen for allogeneic blood and marrow transplantation in patients with non-Hodgkin's lymphoma

2003 • 29 citations

Haemolytic uraemic syndrome and renal dysfunction following BEAC (BCNU, etoposide, ara-C, cyclophosphamide) +/- TBI and autologous BMT for malignant lymphomas.

1993 • 29 citations

Allogeneic hematopoietic stem cell transplantation for progressive follicular lymphoma

2002 • 28 citations

Functional Heterogeneity of the Cerebrovascular Endothelium

1988 • 25 citations

Current status of FK 506 in liver transplantation.

1991 • 24 citations

Serum TNFα levels in patients with acute graft-versus-host disease after bone marrow transplantation

2001 • 23 citations

Role of interleukin-12 in the development of acute graft-versus-host disease in bone marrow transplant patients

1999 • 20 citations

Autoantibody analysis in chronic graft-versus-host disease.

1989 • 19 citations

Cortical Blindness during Chemotherapy

1990 • 18 citations

Reversible Cerebral Lesions Associated with Tiazofurin Usage

1988 • 16 citations

Thrombotic microangiopathy of hyperacute onset after autologous peripheral blood stem cell transplantation in malignant lymphoma

1998 • 11 citations

CHANGES OF CYTOKINES DURING THE COURSE OF GRAFT-VERSUS-HOST DISEASE FOLLOWING BONE MARROW TRANSPLANTATION: A CASE REPORT

2000 • 7 citations

Deleted Work

1955 • 0 citations