Serum levels of cytokines after bone marrow transplantation: increased IL‐8 levels during severe veno‐occlusive disease of the liver

IL-10 inhibits cytokine production by activated macrophages.

1991 • 2,919 citations

Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin

1985 • 2,380 citations

Bone-Marrow Transplantation

1975 • 1,667 citations

Methotrexate and Cyclosporine Compared with Cyclosporine Alone for Prophylaxis of Acute Graft versus Host Disease after Marrow Transplantation for Leukemia

1986 • 1,453 citations

The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

1989 • 1,183 citations

Veno-occlusive Disease of the Liver and Multiorgan Failure after Bone Marrow Transplantation: A Cohort Study of 355 Patients

1993 • 1,173 citations

Intravenous Infusion of Bone Marrow in Patients Receiving Radiation and Chemotherapy

1957 • 1,145 citations

Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

1985 • 1,143 citations

ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE

1987 • 1,108 citations

VENOOCCLUSIVE DISEASE OF THE LIVER FOLLOWING BONE MARROW TRANSPLANTATION

1987 • 898 citations

Venocclusive Disease of the Liver after Bone Marrow Transplantation: Diagnosis, Incidence, and Predisposing Factors

1984 • 845 citations

Acute-phase response of human hepatocytes: Regulation of acute-phase protein synthesis by interleukin-6

1990 • 742 citations

Cyclosporin A mediates immunosuppression of primary cytotoxic T cell responses by impairing the release of interleukin 1 and interleukin 2

1981 • 632 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 617 citations

Tumor necrosis factor/cachectin is an effector of skin and gut lesions of the acute phase of graft-vs.-host disease.

1987 • 609 citations

Increased serum levels of tumor necrosis factor alpha precede major complications of bone marrow transplantation [see comments]

1990 • 591 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 565 citations

Peptide Regulatory Factors

1989 • 498 citations

Infectious Complications of Human Bone Marrow Transplantation

1979 • 423 citations

High levels of interleukin 10 production in vivo are associated with tolerance in SCID patients transplanted with HLA mismatched hematopoietic stem cells.

1994 • 413 citations

Clonable T lymphocytes in T cell-depleted bone marrow transplants correlate with development of graft-v-host disease

1986 • 374 citations

A randomized trial comparing busulfan with total body irradiation as conditioning in allogeneic marrow transplant recipients with leukemia: a report from the Nordic Bone Marrow Transplantation Group

1994 • 341 citations

Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo

1988 • 300 citations

Tumor necrosis factor increases the production of plasminogen activator inhibitor in human endothelial cells in vitro and in rats in vivo

1988 • 232 citations

Hepatic veno-occlusive disease--liver toxicity syndrome after bone marrow transplantation.

1992 • 226 citations

Modulation of acute graft-versus-host-disease after allogeneic bone marrow transplantation by tumor necrosis factor alpha (TNF alpha) release in the course of pretransplant conditioning: role of conditioning regimens and prophylactic application of a monoclonal antibody neutralizing human TNF alpha (MAK 195F)

1995 • 198 citations

Prevention of hepatic veno-occlusive disease after bone marrow transplantation by continuous infusion of low-dose heparin: a prospective, randomized trial [see comments]

1992 • 190 citations

Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease

1992 • 176 citations

Treatment of acute graft-versus-host disease with humanized anti-Tac: an antibody that binds to the interleukin-2 receptor

1994 • 170 citations

Prevention of hepatic veno-occlusive disease after bone marrow transplantation by continuous infusion of low-dose heparin: a prospective, randomized trial [see comments]

1992 • 163 citations

THE CLINICAL COURSE OF 53 PATIENTS WITH VENOCCLUSIVE DISEASE OF THE LIVER AFTER MARROW TRANSPLANTATION

1985 • 159 citations

Hepatic veno-occlusive disease

1986 • 143 citations

Phase I-II trial of a monoclonal anti-tumor necrosis factor alpha antibody for the treatment of refractory severe acute graft-versus-host disease

1992 • 139 citations

TNF alpha levels are increased during bone marrow transplantation conditioning in patients who develop acute GVHD.

1995 • 126 citations

Dissociating graft-vs-host disease from the graft-vs-leukemia effect of allogeneic T cells: the potential role of IL-2.

1992 • 118 citations

Role of tumor necrosis factor alpha in acute graft-versus-host disease and complications following allogeneic bone marrow transplantation.

1993 • 106 citations

Problems of infection after bone marrow transplantation.

1983 • 102 citations

Recombinant human tissue plasminogen activator for the treatment of established severe venocclusive disease of the liver after bone marrow transplantation

1992 • 101 citations

Prevention of graft-versus-host disease with T cell depletion or cyclosporin and methotrexate. A randomized trial in adult leukemic marrow recipients.

1991 • 96 citations

THE RELATIONSHIP OF SERUM IL-6 LEVELS TO ACUTE GRAFT-VERSUS-HOST DISEASE AND HEPATORENAL DISEASE AFTER HUMAN BONE MARROW TRANSPLANTATION

1992 • 92 citations

Review Of The Chemokine Meeting The Third International Symposium Of Chemotactic Cytokines

1993 • 73 citations

Clinical Approach to Infection in the Compromised Host

1988 • 73 citations

Secretion of C-reactive protein becomes more efficient during the course of the acute phase response.

1985 • 66 citations

Hepatic veno-occlusive disease after bone marrow transplant

1993 • 53 citations

A comparison of clinical criteria for the diagnosis of veno-occlusive disease of the liver after bone marrow transplantation.

1992 • 53 citations

SERUM LEVELS OF INTERLEUKIN 6, INTERLEUKIN 8, AND C-REACTIVE PROTEIN AFTER HUMAN ALLOGENEIC BONE MARROW TRANSPLANTATION

1994 • 52 citations

Veno-occlusive disease of the liver complicating bone marrow transplantation.

1994 • 47 citations

Cell-cell matrix and cell-cell interactions during hematopoietic differentiation.

1992 • 43 citations

Monitoring cytokine production in peripheral blood during acute graft-versus-host disease following allogeneic bone marrow transplantation.

1993 • 41 citations

Use of an anti-interleukin-2 receptor monoclonal antibody for GVHD prophylaxis in unrelated donor BMT.

1993 • 40 citations

Cytokines as mediators of graft-versus-host disease.

1988 • 34 citations

Individualized prophylaxis against graft-versus-host disease in leukemic marrow transplant recipients.

1994 • 34 citations

Allogeneic bone marrow transplantation for leukemia: factors of importance for long-term survival and relapse.

1988 • 34 citations

Frequency of Veno-occlusive Disease of the Liver in Bone Marrow Transplantation with a Modified Busulfan/Cyclophosphamide Preparative Regimen

1990 • 34 citations

Value of serum C-reactive protein measurement in the management of bone marrow transplant recipients. Part I: Early transplant period.

1984 • 27 citations

INCREASED LEVELS OF SOLUBLE INTERLEUKIN-2 RECEPTOR IN VENO-OCCLUSIVE DISEASE OF THE LIVER AFTER ALLOGENIC BONE MARROW TRANSPLANTATION

1995 • 23 citations

Use of monoclonal antibodies in vivo as a therapeutic strategy for acute GvHD in matched and mismatched bone marrow transplantation.

1991 • 11 citations