Role of interleukin-12 in the development of acute graft-versus-host disease in bone marrow transplant patients

The expanding universe of T-cell subsets: Th1, Th2 and more

1996 • 3,710 citations

Graft-versus-leukemia reactions after bone marrow transplantation

1990 • 2,781 citations

Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes.

1989 • 1,989 citations

Antitumor and antimetastatic activity of interleukin 12 against murine tumors.

1993 • 1,206 citations

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

1994 • 1,066 citations

T-cell depletion of HLA-identical transplants in leukemia

1991 • 771 citations

Influence of acute and chronic graft-versus-host disease on relapse and survival after bone marrow transplantation from HLA-identical siblings as treatment of acute and chronic leukemia [published erratum appears in Blood 1989 Aug 15;74(3):1180]

1989 • 623 citations

Cytokine dysregulation and acute graft-versus-host disease

1992 • 617 citations

Allogeneic cell therapy with donor peripheral blood cells and recombinant human interleukin-2 to treat leukemia relapse after allogeneic bone marrow transplantation

1996 • 439 citations

Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo

1994 • 373 citations

Natural killer (NK) cell stimulatory factor or IL-12 has differential effects on the proliferation of TCR-alpha beta+, TCR-gamma delta+ T lymphocytes, and NK cells.

1992 • 333 citations

Effects of IL-12 on the response and susceptibility to experimental viral infections.

1994 • 233 citations

Allogeneic cell therapy for relapsed leukemia after bone marrow transplantation with donor peripheral blood lymphocytes.

1995 • 215 citations

Human Marrow Transplantation: An Immunological Perspective

1987 • 136 citations

Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies

1991 • 133 citations

Interleukin-12 inhibits murine graft-versus-host disease

1995 • 128 citations

ENDOGENOUS IFN-GAMMA DURING HUMAN BONE MARROW TRANSPLANTATION

1990 • 110 citations

IL-12 is a central mediator of acute graft-versus-host disease in mice.

1996 • 109 citations

THE RELATIONSHIP OF SERUM IL-6 LEVELS TO ACUTE GRAFT-VERSUS-HOST DISEASE AND HEPATORENAL DISEASE AFTER HUMAN BONE MARROW TRANSPLANTATION

1992 • 92 citations

Application of interleukin 12 to antitumor cytokine and gene therapy

1996 • 43 citations

Successful engraftment of allogeneic CD34-enriched marrow cell transplantation from HLA-mismatched parental donors.

1996 • 31 citations

Interleukin‐12 Augments the Generation of Autologous Tumor‐reactive CD8⁺ Cytotoxic T Lymphocytes from Tumor‐infiltrating Lymphocytes

1995 • 23 citations

The Therapeutic Effect of Interleukin‐12 or Its Antagonist in Transplantation Immunity

1996 • 12 citations

Serum interleukin-12 levels in patients undergoing allogeneic or autologous bone marrow transplantation.

1996 • 11 citations