Vascular Permeability Factor/Vascular Endothelial Cell Growth Factor-mediated Permeability Occurs through Disorganization of Endothelial Junctional Proteins

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1992 • 4,631 citations

Tumor Cells Secrete a Vascular Permeability Factor That Promotes Accumulation of Ascites Fluid

1983 • 3,942 citations

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

1994 • 3,652 citations

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1993 • 3,605 citations

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

Vascular Permeability Factor, an Endothelial Cell Mitogen Related to PDGF

1989 • 2,090 citations

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

1994 • 1,661 citations

Molecular and Biological Properties of the Vascular Endothelial Growth Factor Family of Proteins

1992 • 1,612 citations

Suppression of retinal neovascularization in vivo by inhibition of vascular endothelial growth factor (VEGF) using soluble VEGF-receptor chimeric proteins.

1995 • 1,280 citations

Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor

1995 • 1,026 citations

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1995 • 906 citations

Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.

1992 • 900 citations

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells

1997 • 847 citations

A highly conserved vascular permeability factor secreted by a variety of human and rodent tumor cell lines.

1986 • 641 citations

A novel endothelial-specific membrane protein is a marker of cell-cell contacts.

1992 • 637 citations

Vascular endothelial growth factor. A cytokine modulating endothelial function in rheumatoid arthritis.

1994 • 570 citations

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth.

1996 • 567 citations

A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF.

1995 • 480 citations

Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains

1995 • 480 citations

The Vascular Endothelial Growth Factor Receptor KDR Activates Multiple Signal Transduction Pathways in Porcine Aortic Endothelial Cells

1997 • 436 citations

Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo.

1996 • 420 citations

Intracellular Pool of Vascular Endothelial Growth Factor in Human Neutrophils

1997 • 344 citations

Prevention of Lipopolysaccharide-Induced Lethal Toxicity by Tyrosine Kinase Inhibitors

1994 • 339 citations

Vascular Permeability Factor/Vascular Endothelial Growth Factor: An Important Mediator of Angiogenesis in Malignancy and Inflammation

1995 • 337 citations

Vascular Endothelial Growth Factor Receptor Localization and Activation in Human Trophoblast and Choriocarcinoma Cells1

1994 • 246 citations

Expression of Vascular Endothelial Growth Factor by Human Eosinophils: Upregulation by Granulocyte Macrophage Colony-stimulating Factor and Interleukin-5

1997 • 232 citations

Translational regulation of vascular permeability factor by eukaryotic initiation factor 4E: Implications for tumor angiogenesis

1996 • 199 citations

Human neutrophils secrete vascular endothelial growth factor

1997 • 193 citations

Regulation of Angiogenesis

1997 • 187 citations

Vascular endothelial growth factor mRNA increases in alveolar epithelial cells during recovery from oxygen injury.

1995 • 152 citations

Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro.

1993 • 138 citations

Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: Binding, internalization, degradation, and biological effects

1991 • 128 citations

Interaction of the Flt-1 Tyrosine Kinase Receptor with the p85 Subunit of Phosphatidylinositol 3-Kinase

1995 • 123 citations

Vascular endothelial growth factor affects permeability of brain microvessel endothelial cells in vitro

1996 • 117 citations

An N‐cadherin–like protein contributes to solute barrier maintenance in cultured endothelium

1993 • 92 citations

Role of Cadherin Internalization in Hydrogen Peroxide-Mediated Endothelial Permeability

1998 • 91 citations

Biological properties of VEGF/VPF receptors

1996 • 73 citations

Cytosolic calcium changes in endothelial cells induced by a protein product of human gliomas containing vascular permeability factor activity

1989 • 61 citations

Vascular endothelial growth factor stimulates protein kinase C-dependent phospholipase D activity in endothelial cells.

1996 • 55 citations

Regulation of angiogenesis

1997 • 46 citations

Role of cadherins 5 and 13 in the aortic endothelial barrier

1997 • 42 citations

Involvement of mitogen-activated protein kinase and translocation of cytosolic phospholipase A2 to the nuclear envelope in acetylcholine-induced prostacyclin synthesis in rabbit coronary endothelial cells.

1996 • 38 citations

Early Albumin Leakage in Pulmonary Endothelial Monolayers Exposed to Varying Levels of Hyperoxia

1996 • 7 citations