Malignant Tregs express low molecular splice forms of FOXP3 in Sézary syndrome

Immunologic tolerance maintained by CD25⁺ CD4⁺ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

2001 • 1,515 citations

Nonredundant roles for Stat5a/b in directly regulating Foxp3

2007 • 561 citations

Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells

2005 • 525 citations

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs

2005 • 439 citations

Immunopathogenesis and therapy of cutaneous T cell lymphoma

2005 • 399 citations

Engagement of B7 on effector T cells by regulatory T cells prevents autoimmune disease

2004 • 322 citations

Th2 Cytokine mRNA Expression in Skin in Cutaneous T-Cell Lymphoma

1994 • 271 citations

Analysis of FOXP3 Reveals Multiple Domains Required for Its Function as a Transcriptional Repressor

2006 • 267 citations

FOXP3 modifies the phenotypic and functional properties of regulatory T cells

2007 • 262 citations

Cutaneous T-cell lymphoma: malignant proliferation of T-regulatory cells

2004 • 251 citations

Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome.

1996 • 232 citations

Isoform-Specific Inhibition of RORα-Mediated Transcriptional Activation by Human FOXP3

2008 • 229 citations

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1997 • 226 citations

Infections Complicating Mycosis Fungoides and Sézary Syndrome

1992 • 211 citations

Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function

2007 • 201 citations

Mycosis Fungoides Exhibits a Th1-Type Cell-Mediated Cytokine Profile Whereas Sezary Syndrome Express a Th2-Type Profile

1994 • 179 citations

Down-regulating constitutive activation of the NF-κB canonical pathway overcomes the resistance of cutaneous T-cell lymphoma to apoptosis

2005 • 171 citations

In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3

2004 • 160 citations

Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

2001 • 159 citations

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

2006 • 158 citations

FOXP3+ regulatory T cells in cutaneous T-cell lymphomas: association with disease stage and survival

2007 • 150 citations

Discovery of quinazolines as a novel structural class of potent inhibitors of NF-κB activation

2003 • 150 citations

Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression

2004 • 136 citations

Lack of Phosphotyrosine Phosphatase SHP-1 Expression in Malignant T-Cell Lymphoma Cells Results from Methylation of the SHP-1 Promoter

2000 • 133 citations

STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

2001 • 131 citations

Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides

1992 • 130 citations

A continuous T-cell line from a patient with S�zary syndrome

1987 • 121 citations

Jak3- and JNK-dependent vascular endothelial growth factor expression in cutaneous T-cell lymphoma

2006 • 111 citations

Cutaneous T Cell Lymphoma Reactive CD4+ Cytotoxic T Lymphocyte Clones Display a Th1 Cytokine Profile and Use a Fas-Independent Pathway for Specific Tumor Cell Lysis

2000 • 104 citations

Lack of Suppressive CD4+CD25+FOXP3+ T Cells in Advanced Stages of Primary Cutaneous T-Cell Lymphoma

2006 • 97 citations

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides : tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1997 • 93 citations

Paucity of FOXP3+ cells in skin and peripheral blood distinguishes Sézary syndrome from other cutaneous T-cell lymphomas

2006 • 85 citations

Splice variants of human FOXP3 are functional inhibitors of human CD4⁺ T‐cell activation

2006 • 85 citations

Nonmalignant T cells stimulate growth of T-cell lymphoma cells in the presence of bacterial toxins

2006 • 78 citations

Inhibition of Phosphatidylinositol 3‐Kinase Blocks T Cell Antigen Receptor/CD3‐Induced Activation of the Mitogen‐Activated Kinase Erk2

1996 • 72 citations

Dysregulated Synthesis of Intracellular Type 1 and Type 2 Cytokines by T Cells of Patients with Cutaneous T-Cell Lymphoma

1999 • 70 citations

Cytogenetic Findings in Cell Lines from Cutaneous T-Cell Lymphoma

1994 • 62 citations

Crosstalk between Tumor T Lymphocytes and Reactive T Lymphocytes in Cutaneous T Cell Lymphomas

2001 • 48 citations

Mimotopes for tumor-specific T lymphocytes in human cancer determined with combinatorial peptide libraries

2001 • 47 citations

A bioassay for the measurement of human interleukin-4

1990 • 36 citations

Common clonal chromosome aberrations in cytokine-dependent continuous human T-lymphocyte cell lines

1995 • 31 citations

Association of the human CD3-zeta chain with the alpha beta-T cell receptor/CD3 complex. Clues from a T cell variant with a mutated T cell receptor-alpha chain.

1990 • 29 citations

Overexpression of SOCS3 is associated with decreased survival in a cohort of patients with de novo follicular lymphoma

2006 • 23 citations

Future Perspectives in the Treatment of Cutaneous T-Cell Lymphoma (CTCL)

2006 • 21 citations

Immunopathogenesis of cutaneous T-cell lymphomas

2003 • 15 citations

Advances in understanding the immunobiology and immunotherapy of cutaneous T-cell lymphoma.

2004 • 6 citations

Cited By (0)

Loading...