In vivo activation of STAT3 in cutaneous T-cell lymphoma. Evidence for an antiapoptotic function of STAT3

STATs: transcriptional control and biological impact

2002 • 3,050 citations

Stat3 as an Oncogene

1999 • 2,770 citations

Constitutive Activation of Stat3 Signaling Confers Resistance to Apoptosis in Human U266 Myeloma Cells

1999 • 1,655 citations

What does Stat3 do?

2002 • 810 citations

What does Stat3 do?

2002 • 685 citations

Two Signals Are Necessary for Cell Proliferation Induced by a Cytokine Receptor gp130: Involvement of STAT3 in Anti-Apoptosis

1996 • 661 citations

Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesisin vivo

2000 • 594 citations

A central role for Stat3 in IL-6-induced regulation of growth and differentiation in M1 leukemia cells.

1996 • 589 citations

Stat3 Activation Is Responsible for IL-6-Dependent T Cell Proliferation Through Preventing Apoptosis: Generation and Characterization of T Cell-Specific Stat3-Deficient Mice

1998 • 571 citations

Keratinocyte-specific ablation of Stat3 exhibits impaired skin remodeling, but does not affect skin morphogenesis

1999 • 521 citations

Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3

1999 • 481 citations

STAT3 activation is a critical step in gp130-mediated terminal differentiation and growth arrest of a myeloid cell line.

1996 • 345 citations

Signal transducer and activator of transcription proteins in leukemias

2003 • 320 citations

STAT family of transcription factors in cytokine-mediated biological responses

2000 • 311 citations

Mycosis fungoides and Sezary syndrome [see comments]

1996 • 284 citations

The Role of STATs in Apoptosis

2002 • 275 citations

Multilevel Dysregulation of STAT3 Activation in Anaplastic Lymphoma Kinase-Positive T/Null-Cell Lymphoma

2002 • 273 citations

The Jak-Stat Pathway: Cytokine Signalling from the Receptor to the Nucleus

1999 • 263 citations

Negative regulation of cytokine signaling

2001 • 259 citations

Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome.

1996 • 232 citations

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: Tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1997 • 226 citations

Inhibition of constitutively activated Stat3 correlates with altered Bcl-2/Bax expression and induction of apoptosis in mycosis fungoides tumor cells

1999 • 196 citations

Constitutive STAT3-activation in Sezary syndrome: tyrphostin AG490 inhibits STAT3-activation, interleukin-2 receptor expression and growth of leukemic Sezary cells

2001 • 159 citations

Inhibition of protein phosphatase 2A induces serine/threonine phosphorylation, subcellular redistribution, and functional inhibition of STAT3

1999 • 134 citations

STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma

2001 • 131 citations

Establishment of two continuous T-cell strains from a single plaque of a patient with mycosis fungoides

1992 • 130 citations

Signal transducers and activators of transcription as regulators of growth, apoptosis and breast development

2000 • 113 citations

Negative Regulators of Cytokine Signaling

2001 • 106 citations

Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides : tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines

1997 • 93 citations

Spontaneous interleukin-5 production in cutaneous T-cell lymphoma lines is mediated by constitutively activated Stat3

2002 • 66 citations

STAT3 activation accompanies keratinocyte differentiation.

1998 • 50 citations

Interferon-Alpha Induces Transient Suppressors of Cytokine Signalling Expression in Human T Cells

2001 • 38 citations

STAT3 activation is a critical step in gp130 mediated-terminal differentiation and growth arrest of a myeloid cell line

2000 • 31 citations

Cutaneous T‐cell lymphoma

2003 • 23 citations

Cutaneous T-cell lymphomas

1998 • 15 citations