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The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs

Data up to Jan 2025

Published2005
Citations439
References36

Total Citations Per Year

Abstract

References (36)

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N<scp>aturally</scp>A<scp>rising</scp>CD4+R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

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Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human Blood

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Human Cd25+Cd4+ T Regulatory Cells Suppress Naive and Memory T Cell Proliferation and Can Be Expanded in Vitro without Loss of Function

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Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level

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Human CD25+CD4+ T Suppressor Cell Clones Produce Transforming Growth Factor β, but not Interleukin 10, and Are Distinct from Type 1 T Regulatory Cells

2002 • 440 citations

Induction offoxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants

2004 • 416 citations

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

2004 • 415 citations

The Role of IL-10 and TGF-β in the Differentiation and Effector Function of T Regulatory Cells

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Human CD4+CD25+ regulatory T cells

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Defective Suppressor Function of Human CD4+ CD25+ Regulatory T Cells in Autoimmune Polyglandular Syndrome Type II

2004 • 359 citations

HIV Infection of Naturally Occurring and Genetically Reprogrammed Human Regulatory T-cells

2004 • 308 citations

In vitro–expanded human CD4+CD25+ T-regulatory cells can markedly inhibit allogeneic dendritic cell–stimulated MLR cultures

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Alloantigen specific CD8+CD28− FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivity

2004 • 257 citations

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2003 • 190 citations

Induction of allopeptide-specific human CD4+CD25+ regulatory T cells ex vivo

2003 • 190 citations

Dominant transplantation tolerance impairs CD8+ T cell function but not expansion

2002 • 161 citations

In vivo expansion of CD4+CD45RO-CD25+ T cells expressing foxP3 in IL-2-treated HIV-infected patients

2005 • 123 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 95 citations

Superantigen-Induced Regulatory T Cells Display Different Suppressive Functions in the Presence or Absence of Natural CD4+CD25+ Regulatory T Cells In Vivo

2003 • 59 citations

CD4+CD25+ and CD4+CD25− T Cells Act Respectively as Inducer and Effector T Suppressor Cells in Superantigen-Induced Tolerance

2003 • 48 citations

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The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs (2005) – Journal of Clinical Investigation | Metascience Observatory Explorer