Isoform-Specific Inhibition of RORα-Mediated Transcriptional Activation by Human FOXP3

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

2003 • 7,902 citations

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

2003 • 7,470 citations

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

2006 • 4,815 citations

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

2001 • 3,260 citations

An essential role for Scurfin in CD4+CD25+ T regulatory cells

2003 • 2,825 citations

A signature motif in transcriptional co-activators mediates binding to nuclear receptors

1997 • 2,100 citations

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

2001 • 1,831 citations

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

2001 • 1,659 citations

Immunologic tolerance maintained by CD25⁺ CD4⁺ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

2001 • 1,515 citations

Natural versus adaptive regulatory T cells

2003 • 1,363 citations

Regulatory T Cells in Autoimmmunity

2000 • 1,267 citations

Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

2003 • 1,252 citations

Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance

1999 • 1,223 citations

FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT

2006 • 1,135 citations

Structure and specificity of nuclear receptor–coactivator interactions

1998 • 922 citations

An essential function for the nuclear receptor RORγt in the generation of fetal lymphoid tissue inducer cells

2003 • 917 citations

JM2, encoding a fork head–related protein, is mutated in X-linked autoimmunity–allergic disregulation syndrome

2000 • 909 citations

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

2004 • 805 citations

Requirement for RORγ in Thymocyte Survival and Lymphoid Organ Development

2000 • 714 citations

The CoRNR motif controls the recruitment of corepressors by nuclear hormone receptors

1999 • 637 citations

Hormone-Dependent Coactivator Binding to a Hydrophobic Cleft on Nuclear Receptors

1998 • 580 citations

Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation

2001 • 551 citations

Foxp3 interacts with nuclear factor of activated T cells and NF-κB to repress cytokine gene expression and effector functions of T helper cells

2005 • 525 citations

Molecular determinants of nuclear receptor-corepressor interaction

1999 • 516 citations

The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs

2005 • 439 citations

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans

2004 • 415 citations

Mechanism of corepressor binding and release from nuclear hormone receptors

1999 • 414 citations

Human CD4+CD25+ regulatory T cells

2004 • 389 citations

X-linked lymphoreticular disease in the scurfy (sf) mutant mouse.

1991 • 339 citations

Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFκB

2007 • 326 citations

Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis

2000 • 308 citations

Analysis of FOXP3 Reveals Multiple Domains Required for Its Function as a Transcriptional Repressor

2006 • 267 citations

The orphan nuclear receptor RORα is a negative regulator of the inflammatory response

2001 • 265 citations

Regulatory T cells in autoimmunity

2007 • 228 citations

The ROR nuclear orphan receptor subfamily: Critical regulators of multiple biological processes

2001 • 227 citations

AF-2 Activity and Recruitment of Steroid Receptor Coactivator 1 to the Estrogen Receptor Depend on a Lysine Residue Conserved in Nuclear Receptors

1997 • 214 citations

Disruption of retinoid-related orphan receptor β changes circadian behavior, causes retinal degeneration and leads to vacillans phenotype in mice

1998 • 214 citations

Activation of Nuclear Receptors

2003 • 181 citations

The mutant leucine-zipper domain impairs both dimerization and suppressive function of Foxp3 in T cells

2006 • 88 citations

Coactivators for the Orphan Nuclear Receptor RORα

1999 • 83 citations

Lymphocyte Development and Function in the Absence of Retinoic Acid-Related Orphan Receptor α

2004 • 81 citations

The Structural Integrity of RORα Isoforms Is Mutated instaggererMice: Cerebellar Coexpression of RORα1 and RORα4

1997 • 75 citations

Retinoid-related orphan receptors (RORs): roles in cell survival, differentiation and disease

2002 • 53 citations

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome: a model of immune dysregulation

2002 • 46 citations

RORα1 and RORα4 suppress TNF‐α‐induced VCAM‐1 and ICAM‐1 expression in human endothelial cells

2003 • 34 citations

Characterization of the Retinoid Orphan-Related Receptor-α Coactivator Binding Interface: A Structural Basis for Ligand-Independent Transcription

2002 • 28 citations