Skin and hair follicle integrity is crucially dependent on β1 integrin expression on keratinocytes
Data up to Jan 2025
Total Citations Per Year
Abstract
References (65)
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction
1987 • 64,270 citations
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
1987 • 45,673 citations
Calcium's Role in Mechanotransduction during Muscle Development
2014 • 14,293 citations
Integrins: Versatility, modulation, and signaling in cell adhesion
1992 • 9,986 citations
Integrin Signaling
1999 • 3,705 citations
The Biology of Hair Follicles
1999 • 1,312 citations
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression
1993 • 1,102 citations
Strain-Dependent Epithelial Defects in Mice Lacking the EGF Receptor
1995 • 1,016 citations
Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.
1994 • 969 citations
The secret life of the hair follicle
1992 • 919 citations
Stem cell patterning and fate in human epidermis
1995 • 788 citations
Sonic hedgehog signaling is essential for hair development
1998 • 742 citations
Consequences of lack of beta 1 integrin gene expression in mice.
1995 • 724 citations
Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis
1996 • 708 citations
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 • 659 citations
The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family*
1999 • 567 citations
Absence of integrin α6 leads to epidermolysis bullosa and neonatal death in mice
1996 • 539 citations
DIFFERENTIAL REGULATION OF PRO-INFLAMMATORY CYTOKINES DURING WOUND HEALING IN NORMAL AND GLUCOCORTICOID-TREATED MICE
1996 • 492 citations
Essential Role forSonic hedgehogduring Hair Follicle Morphogenesis
1999 • 489 citations
The keratinocyte handbook
1995 • 428 citations
Identification of a major keratinocyte cell envelope protein, loricrin
1990 • 420 citations
α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane
1997 • 407 citations
Epithelial detachment due to absence of hemidesmosomes in integrin β4 null mice
1996 • 402 citations
Transforming growth factor-beta: a general review.
1996 • 400 citations
A Role for Dystroglycan in Basement Membrane Assembly
1998 • 387 citations
Patterned acquisition of skin barrier function during development
1998 • 384 citations
Fetal and Adult Hematopoietic Stem Cells Require β1 Integrin Function for Colonizing Fetal Liver, Spleen, and Bone Marrow
2000 • 371 citations
The Connective Tissue Growth Factor/Cysteine- Rich 61/Nephroblastoma Overexpressed (CCN) Family
1999 • 368 citations
Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.
1988 • 359 citations
Analysis of apoptosis during hair follicle regression (catagen)
1997 • 353 citations
Transforming Growth Factors β1, β2, and β3 and Their Receptors Are Differentially Regulated during Normal and Impaired Wound Healing
1996 • 349 citations
Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins.
1991 • 305 citations
Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis
1995 • 303 citations
A single EGF-like motif of laminin is responsible for high affinity nidogen binding.
1993 • 269 citations
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.
1993 • 252 citations
Expression of a dominant negative mutant of epidermal growth factor receptor in the epidermis of transgenic mice elicits striking alterations in hair follicle development and skin structure.
1995 • 247 citations
Signaling via β1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro
1999 • 246 citations
The secret life of the hair follicle
1992 • 243 citations
Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation.
1993 • 240 citations
Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation
1994 • 223 citations
Biology and function of hemidesmosomes
1999 • 210 citations
Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair
1999 • 209 citations
Sequences 5′ of the bovine keratin 5 gene direct tissue- and cell-type-specific expression of a lacZ gene in the adult and during development
1994 • 208 citations
Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin β4 cytoplasmic domain
1998 • 197 citations
β1 Integrin Is Essential for Teratoma Growth and Angiogenesis
1997 • 185 citations
PATHOGENESIS OF SCLERODERMA
1996 • 178 citations
The Role of the Hairless (hr) Gene in the. Regulation of Hair Follicle Catagen Transformation
1999 • 170 citations
Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes
1996 • 165 citations
Embryology of Hair
1958 • 165 citations
[1] Isolation and utilization of epidermal keratinocytes for oncogene research
1995 • 158 citations
Differentiation of Embryonal Stem Cells into Keratinocytes: Comparison of Wild-Type and β1Integrin-Deficient Cells
1996 • 154 citations
Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas.
1993 • 153 citations
Splitting Hairs
1998 • 151 citations
Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differentiation.
1995 • 134 citations
Dexamethasone Is a Novel Potent Inducer of Connective Tissue Growth Factor Expression
1998 • 132 citations
Laminins of the dermo–epidermal junction
1999 • 127 citations
Genetic analysis of β1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules
1997 • 109 citations
Deficiency of β1 Integrins in Teratoma Interferes with Basement Membrane Assembly and Laminin-1 Expression
1998 • 68 citations
Mast cells as modulators of hair follicle cycling
1995 • 66 citations
The extracellular matrix and mitogenic growth factors control G1 phase cyclins and cyclin-dependent kinase inhibitors
1997 • 64 citations
A study of the post‐natal development of the skin and hair of the mouse
1941 • 43 citations
Experimental Dermatology
2010 • 33 citations
The distribution of ? 2 ? 1, ? 3 ? 1 and ? 6 ? 4 integrins identifies distinct subpopulations of basal keratinocytes in the outer root sheath of the human anagen hair follicle
1997 • 31 citations
Differences Between Connective Tissue-Epithelial Junctions in Human Skin and the Anagen Hair Follicle
1995 • 26 citations
Gene-knockout mice with abnormal epidermal and hair follicular development
1998 • 11 citations